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European Radiology

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01-06-2016 | Neuro

Endovascular mechanical recanalization of acute ischaemic stroke in octogenarians

Authors: Erasmia Broussalis, F. Weymayr, W. Hitzl, A. F. Unterrainer, E. Trinka, M. Killer

Published in: European Radiology | Issue 6/2016

Abstract

Background

Multiple studies have shown a clinical benefit of thrombectomy in acute ischaemic stroke, but most of them excluded octogenarians. The purpose of this study was to compare the outcomes between octogenarians and younger patients after thrombectomy.

Materials and methods

One hundred and sixty-six patients with large cerebral artery occlusion and consecutive thrombectomy were evaluated and divided into two patient age groups: younger than 80 years and older than 80 years. We compared recanalization rates, complications experienced, disability, death after discharge and at a 90-day follow-up between these age groups.

Results

Sixty-eight percent of octogenarians and 72 % of younger patients were registered with successful recanalization (p = 1.0). There was no significant difference in symptomatic intracerebral haemorrhage between the groups (p = 0.32). However, octogenarians had a significantly lower rate of good clinical outcome (24 % vs. 48 %; p = 0.008) and a higher mortality rate (36 % vs. 12 %; p = 0.0013).

Conclusion

Octogenarians have a lower chance of good clinical outcome and a higher mortality rate despite successful recanalization. Nevertheless, 24 % of octogenarians were documented with mRS ≤2. As this age group of octogenarians will grow prospectively, careful patient selection should be mandatory when considering octogenarians for thrombectomy.

Key Points

• Careful patient selection for thrombectomy should be mandatory in octogenarians.

• Octogenarians have a higher mortality rate despite successful recanalization.

• Nearly one-third of octogenarians were documented with a good clinical outcome.

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Title: Endovascular mechanical recanalization of acute ischaemic stroke in octogenarians
Authors: Erasmia Broussalis
F. Weymayr
W. Hitzl
A. F. Unterrainer
E. Trinka
M. Killer
Publication date: 01-06-2016
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 6/2016
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3969-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Endovascular mechanical recanalization of acute ischaemic stroke in octogenarians

Abstract

Background

Materials and methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Materials and methods

Results

Conclusion

Key Points

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