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European Radiology

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01-09-2011 | Pediatric

Interactive magnetic resonance voiding cystourethrography (iMRVC) for vesicoureteric reflux (VUR) in unsedated infants: a feasibility study

Authors: Owen J. Arthurs, Andrea D. Edwards, Ilse Joubert, Martin J. Graves, Pat A K Set, David J. Lomas

Published in: European Radiology | Issue 9/2011

Abstract

Objectives

The current reference standard for diagnosing vesicoureteric reflux is the X-ray-based Micturating CystoUrethroGram (MCUG). The aim of this study was to evaluate the feasibility of performing interactive Magnetic Resonance voiding cysto-urethrography (iMRVC) in un-sedated infants.

Methods

Twelve infants underwent conventional single-cycle MCUG followed by iMRVC. In iMRVC, patients were examined using an in-house developed fluoroscopic pulse sequence, which allows on-the-fly control of image contrast and geometry. A single acquisition was performed during bladder filling, during and after micturition, with interactive control over imaging parameters. Images were assessed for diagnostic quality and presence of VUR.

Results

Every case of reflux identified with MCUG was identified on iMRVC (100% sensitivity). Over 24 renal units, there was 88% concordance (21/24) according to the presence of reflux between the two methods. There were three “false positives” detected by MRI, giving a specificity of 83.3%, PPV of 66.7% and NPV of 100%.

Conclusion

iMRVC is a feasible method for evaluating the renal tract in infants without the need for radiation or sedation. A formal evaluation is required to establish its diagnostic potential.

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Title: Interactive magnetic resonance voiding cystourethrography (iMRVC) for vesicoureteric reflux (VUR) in unsedated infants: a feasibility study
Authors: Owen J. Arthurs
Andrea D. Edwards
Ilse Joubert
Martin J. Graves
Pat A K Set
David J. Lomas
Publication date: 01-09-2011
Publisher: Springer-Verlag
Published in: European Radiology / Issue 9/2011
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-011-2124-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Interactive magnetic resonance voiding cystourethrography (iMRVC) for vesicoureteric reflux (VUR) in unsedated infants: a feasibility study

Abstract

Objectives

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusion

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