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Rheumatology International
Published in: Rheumatology International 7/2008

Open Access 01-05-2008 | Case Report

Idiopathic hypertrophic cranial pachymeningitis treated by oral methotrexate: a case report and review of literature

Authors: T. Bosman, C. Simonin, D. Launay, S. Caron, A. Destée, L. Defebvre

Published in: Rheumatology International | Issue 7/2008

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Abstract

Idiopathic hypertrophic cranial pachymeningitis (IHCP) is a rare clinical entity, characterized by a chronic inflammation causing thickening of the dura. Adequate therapeutic management is still a matter of debate. We present a patient with an IHCP, non-responsive to corticotherapy. Oral methotrexate was introduced (12.5 mg weekly) and total remission was observed after 6 weeks, both clinically and after neuro-imaging. We conclude that methotrexate can be effective and a therapeutical option in patients with IHCP who are resistant to corticotherapy or present major side-effects of chronic corticosteroids use.
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Metadata
Title
Idiopathic hypertrophic cranial pachymeningitis treated by oral methotrexate: a case report and review of literature
Authors
T. Bosman
C. Simonin
D. Launay
S. Caron
A. Destée
L. Defebvre
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 7/2008
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-007-0504-5

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