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Annals of Hematology
Published in: Annals of Hematology 3/2018

01-03-2018 | Letter to the Editor

Simultaneous occurrence of two distinct leukemic clones with PML-RARα and RUNX1-RUNX1T1 in a case of acute myeloid leukemia

Authors: Haigang Shao, Qian Yang, Ping Zhang, Hengfang Liu, Chunxiao Wu, Jiannong Cen, Huiying Qiu, Suning Chen, Jinlan Pan

Published in: Annals of Hematology | Issue 3/2018

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Excerpt

Dear Editor, …
Literature
1.
Arber DA, Orazi A, Hasserjian R et al (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127(20):2391–2405CrossRefPubMed
2.
Uz B, Eliaçık E, Işık A et al (2013) Co-expression of t(15;17) and t(8;21) in a case of acute Promyelocytic leukemia: review of the literature. Turk J Haematol 30(4):400–404CrossRefPubMedPubMedCentral
3.
Stavroyianni N, Kalmantis T, Yataganas X (1999) Simultaneous PML/RARa and AML1/ETO gene rearrangements in a patient with acute myeloid leukemia. Leukemia 13(8):1294–1295CrossRefPubMed
4.
Abreu e Lima RS, Baruffi MR, de Lima AS et al (2005) The co-expression of PML/RAR alpha and AML1/ETO fusion genes is associated with ATRA resistance. Br J Haematol 128(3):407–409CrossRefPubMed
5.
Movafagh A, Varma N, Varma S (1996) Co-expression of two FAB-specific chromosome changes, t(15;17) and t(8;21), in a case of acute promyelocytic leukemia. Ann Hematol 72(6):375–377CrossRefPubMed
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Neto WK, Serpa M, Sanabani SS et al (2010) Early detection of t(8;21) chromosomal translocations during treatment of PML-RARA positive acute Promyelocytic leukemia: a case study. Clin Med Insights Oncol 4:163–170CrossRefPubMedPubMedCentral
7.
Bonomia R, Giordanoa H, Morenoa MP et al (2000) Simultaneous PML/RARalpha and AML1/ETO expression with t(15;17) at onset and relapse with only t(8;21) in an acute promyelocytic leukemia patient. Cancer Genet Cytogenet 123(1):41–43CrossRef
Metadata
Title
Simultaneous occurrence of two distinct leukemic clones with PML-RARα and RUNX1-RUNX1T1 in a case of acute myeloid leukemia
Authors
Haigang Shao
Qian Yang
Ping Zhang
Hengfang Liu
Chunxiao Wu
Jiannong Cen
Huiying Qiu
Suning Chen
Jinlan Pan
Publication date
01-03-2018
Publisher
Springer Berlin Heidelberg
Published in
Annals of Hematology / Issue 3/2018
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-017-3169-5

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Keynote webinar | Spotlight on medication adherence

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WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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