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CardioVascular and Interventional Radiology

Published in:

01-10-2014 | Clinical Investigation

Risk Factors for Systemic Air Embolism as a Complication of Percutaneous CT-guided Lung Biopsy: Multicenter Case-control Study

Authors: Hiroaki Ishii, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Hidefumi Mimura, Kotaro Yasui, Tetsuya Doke, Takashi Mukai, Hironori Kurokawa, Yoshitomo Ando, Soichiro Hase, Toshihiro Iguchi, Takayuki Yabuki, Kenichi Omae, Nobuhisa Tajiri, Toshiharu Mitsuhashi, Susumu Kanazawa

Published in: CardioVascular and Interventional Radiology | Issue 5/2014

Abstract

Purpose

To determine risk factors for systemic air embolism by percutaneous computed tomography (CT)-guided lung biopsy.

Methods

This case-control study used data from 2216 percutaneous lung biopsy procedures performed over 11 years at 12 institutions in Japan. Systemic air embolism was identified by retrospective review of CT images obtained during and immediately after the procedures. To fulfill our objective, multiple variables were compared between cases and controls with univariate analyses by using Student’s t test and Fisher’s exact test for numerical and categorical values, respectively. Multivariate logistic regression analysis was then performed using selected variables.

Results

Ten cases of systemic air embolism and 2,206 controls were identified. Univariate analyses showed that the lesions in the lower lobe (P = 0.025) and occurrence of parenchymal hemorrhage (P = 0.019) were significant risk factors. Multivariate analysis showed that the use of a larger biopsy needle was a significant risk factor (P = 0.014).

Conclusion

Parenchymal hemorrhage during the procedure, lesions in the lower lobe, and the use of larger biopsy needles may be risk factors for systemic air embolism by percutaneous CT-guided lung biopsy. Our findings may provide clues toward minimizing the risk of this complication.

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Title: Risk Factors for Systemic Air Embolism as a Complication of Percutaneous CT-guided Lung Biopsy: Multicenter Case-control Study
Authors: Hiroaki Ishii
Takao Hiraki
Hideo Gobara
Hiroyasu Fujiwara
Hidefumi Mimura
Kotaro Yasui
Tetsuya Doke
Takashi Mukai
Hironori Kurokawa
Yoshitomo Ando
Soichiro Hase
Toshihiro Iguchi
Takayuki Yabuki
Kenichi Omae
Nobuhisa Tajiri
Toshiharu Mitsuhashi
Susumu Kanazawa
Publication date: 01-10-2014
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 5/2014
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-013-0808-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Risk Factors for Systemic Air Embolism as a Complication of Percutaneous CT-guided Lung Biopsy: Multicenter Case-control Study

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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