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CardioVascular and Interventional Radiology

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01-10-2014 | Clinical Investigation

Evaluation of Split Renal Function Before and After Renal Arterial Embolization for Angiomyolipoma Using Absolute Ethanol

Authors: Yasutaka Baba, Sadao Hayashi, Shunichiro Ikeda, Megumi Jinguji, Masatoyo Nakajo, Masayuki Nakajo

Published in: CardioVascular and Interventional Radiology | Issue 5/2014

Abstract

Purpose

Transcatheter arterial embolization (TAE) with absolute ethanol is widely accepted as a therapeutic procedure for renal angiomyolipoma (AML). We aim to evaluate the split renal function before and after AE for renal AML by using 99m-technetium (^99mTc)-mercaptoacetyltriglycine 3 (MAG3) renography.

Methods

This study was approved by the Institutional Review Board. The study population comprised 11 renal AML patients (three males, eight females, age 55.1 ± 13.8 years, AML in eight right and three left kidneys) who received unilateral renal TAE with absolute ethanol from April 2002 to January 2013. Blood renal function (i.e. serum creatinine and estimated glomerular filtration rate [eGFR] and split effective renal plasma flow [ERPF]) calculated on ^99mTc-MAG3 renography was compared before and within 1 week after renal AE. Statistical analysis was calculated using Wilcoxon signed-ranked test.

Results

TAE for renal AML was technically successful in all patients. Serum creatinine and eGFR did not change before and after TAE. ERPF on the embolized kidney did not change before (127.3 ± 60.8 ml/min) and after (127.6 ± 47.4 ml/min) TAE (p = 0.9726). ERPF on the nonembolized kidney showed a statistically significant increase before (152.5 ± 46.8 ml/min) and within 1 week after (169.1 ± 41.5 ml/min) TAE (p = 0.0093 and p < 0.05, respectively).

Conclusion

TAE for renal AML may not induce renal dysfunction on the embolized kidney and may immediately increase the renal blood flow of the nonembolized kidney.

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Title: Evaluation of Split Renal Function Before and After Renal Arterial Embolization for Angiomyolipoma Using Absolute Ethanol
Authors: Yasutaka Baba
Sadao Hayashi
Shunichiro Ikeda
Megumi Jinguji
Masatoyo Nakajo
Masayuki Nakajo
Publication date: 01-10-2014
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology / Issue 5/2014
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-013-0780-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluation of Split Renal Function Before and After Renal Arterial Embolization for Angiomyolipoma Using Absolute Ethanol

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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