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Published in: Abdominal Radiology 9/2016

01-09-2016 | JSAR

A case of polypoid endometriosis with malignant transformation

Authors: Mayumi Takeuchi, Kenji Matsuzaki, Yoshimi Bando, Masato Nishimura, Akiko Yoneda, Masafumi Harada

Published in: Abdominal Radiology | Issue 9/2016

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Abstract

Polypoid endometriosis is a benign, rare variant of endometriosis which forms multiple polypoid nodules in the female pelvis mimicking malignant tumors; however, it may rarely cause malignant transformation. We report magnetic resonance imaging findings of a case of polypoid endometriosis with malignant transformation. Multiple high-signal intensity polypoid nodules in the cul-de-sac surrounded by low-signal intensity rim-like fibrous adhesion protruding to the posterior wall of the uterine body were demonstrated on T2-weighted images. The polypoid nodules showed weak contrast enhancement compared with that of uterine myometrium on post-contrast T1-weighted images, and slight high signal intensity on diffusion-weighted images with relatively high mean apparent diffusion coefficient. Reported cases of polypoid endometriosis showed intense contrast enhancement similar to that of uterine myometrium, and weak contrast enhancement similar to that of endometrial carcinoma may be suggestive for malignant transformation of polypoid endometriosis.
Literature
1.
go back to reference Parker RL, Dadmanesh F, Young RH, Clement PB (2004) Polypoid endometriosis: a clinicopathologic analysis of 24 cases and a review of the literature. Am J Surg Pathol 28:285–297CrossRefPubMed Parker RL, Dadmanesh F, Young RH, Clement PB (2004) Polypoid endometriosis: a clinicopathologic analysis of 24 cases and a review of the literature. Am J Surg Pathol 28:285–297CrossRefPubMed
2.
go back to reference Hansen K, Simon RA, Lawrence WD, Quddus MR (2012) Unilateral pelvic mass presenting in postmenopausal patients: report of two unusual cases. Ann Diagn Pathol 16:298–301CrossRef Hansen K, Simon RA, Lawrence WD, Quddus MR (2012) Unilateral pelvic mass presenting in postmenopausal patients: report of two unusual cases. Ann Diagn Pathol 16:298–301CrossRef
4.
go back to reference Kozawa E, Inoue K, Iwasa N, et al. (2012) MR imaging of polypoid endometriosis of the ovary. Magn Reson Med Sci 11:201–204CrossRefPubMed Kozawa E, Inoue K, Iwasa N, et al. (2012) MR imaging of polypoid endometriosis of the ovary. Magn Reson Med Sci 11:201–204CrossRefPubMed
5.
go back to reference Kraft JK, Hughes T (2006) Polypoid endometriosis and other benign gynaecological complications associated with tamoxifen therapy—a case to illustrate features on magnetic resonance imaging. Clin Radiol 61:198–201CrossRefPubMed Kraft JK, Hughes T (2006) Polypoid endometriosis and other benign gynaecological complications associated with tamoxifen therapy—a case to illustrate features on magnetic resonance imaging. Clin Radiol 61:198–201CrossRefPubMed
7.
go back to reference Yamada Y, Miyamoto T, Horiuchi A, Ohya A, Shiozawa T (2014) Polypoid endometriosis of the ovary mimicking ovarian carcinoma dissemination: a case report and literature review. J Obstet Gynaecol Res 40:1426–1430. doi:10.1111/jog.12358 CrossRefPubMed Yamada Y, Miyamoto T, Horiuchi A, Ohya A, Shiozawa T (2014) Polypoid endometriosis of the ovary mimicking ovarian carcinoma dissemination: a case report and literature review. J Obstet Gynaecol Res 40:1426–1430. doi:10.​1111/​jog.​12358 CrossRefPubMed
8.
go back to reference Syrcle SM, Pelch KE, Schroder AL, et al. (2011) Altered gene expression profile in vaginal polypoid endometriosis resembles peritoneal endometriosis and is consistent with increased local estrogen production. Gynecol Obstet Invest 71:77–86. doi:10.1159/000320736 CrossRefPubMed Syrcle SM, Pelch KE, Schroder AL, et al. (2011) Altered gene expression profile in vaginal polypoid endometriosis resembles peritoneal endometriosis and is consistent with increased local estrogen production. Gynecol Obstet Invest 71:77–86. doi:10.​1159/​000320736 CrossRefPubMed
9.
go back to reference Takeuchi M, Matsuzaki K, Nishitani H (2009) Diffusion-weighted magnetic resonance imaging of endometrial cancer: differentiation from benign endometrial lesions and preoperative assessment of myometrial invasion. Acta Radiol 50:947–953. doi:10.1080/02841850903099981 CrossRefPubMed Takeuchi M, Matsuzaki K, Nishitani H (2009) Diffusion-weighted magnetic resonance imaging of endometrial cancer: differentiation from benign endometrial lesions and preoperative assessment of myometrial invasion. Acta Radiol 50:947–953. doi:10.​1080/​0284185090309998​1 CrossRefPubMed
10.
go back to reference Wang J, Yu T, Bai R, et al. (2010) The value of the apparent diffusion coefficient in differentiating stage IA endometrial carcinoma from normal endometrium and benign diseases of the endometrium: initial study at 3-T magnetic resonance scanner. J Comput Assist Tomogr 34:332–337. doi:10.1097/RCT.0b013e3181d0f666 CrossRefPubMed Wang J, Yu T, Bai R, et al. (2010) The value of the apparent diffusion coefficient in differentiating stage IA endometrial carcinoma from normal endometrium and benign diseases of the endometrium: initial study at 3-T magnetic resonance scanner. J Comput Assist Tomogr 34:332–337. doi:10.​1097/​RCT.​0b013e3181d0f666​ CrossRefPubMed
12.
go back to reference Imaoka I, Sugimura K, Masui T, et al. (1999) Abnormal uterine cavity: differential diagnosis with MR imaging. Magn Reson Imaging 17:1445–1455CrossRefPubMed Imaoka I, Sugimura K, Masui T, et al. (1999) Abnormal uterine cavity: differential diagnosis with MR imaging. Magn Reson Imaging 17:1445–1455CrossRefPubMed
13.
go back to reference Park BK, Kim B, Park JM, et al. (2006) Differentiation of the various lesions causing an abnormality of the endometrial cavity using MR imaging: emphasis on enhancement patterns on dynamic studies and late contrast-enhanced T1-weighted images. Eur Radiol 16:1591–1598CrossRef Park BK, Kim B, Park JM, et al. (2006) Differentiation of the various lesions causing an abnormality of the endometrial cavity using MR imaging: emphasis on enhancement patterns on dynamic studies and late contrast-enhanced T1-weighted images. Eur Radiol 16:1591–1598CrossRef
Metadata
Title
A case of polypoid endometriosis with malignant transformation
Authors
Mayumi Takeuchi
Kenji Matsuzaki
Yoshimi Bando
Masato Nishimura
Akiko Yoneda
Masafumi Harada
Publication date
01-09-2016
Publisher
Springer US
Published in
Abdominal Radiology / Issue 9/2016
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-016-0696-9

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