Skip to main content
Top
Published in: Abdominal Radiology 2/2009

01-04-2009

MR imaging in the triage of pregnant patients with acute abdominal and pelvic pain

Authors: Aytekin Oto, Randy D. Ernst, Labib M. Ghulmiyyah, Thomas K. Nishino, Douglas Hughes, Gregory Chaljub, George Saade

Published in: Abdominal Radiology | Issue 2/2009

Login to get access

Abstract

Purpose

To retrospectively assess the performance of MR imaging in the evaluation and triage of pregnant patients presenting with acute abdominal or pelvic pain.

Method and materials

MRI studies of pregnant patients who were referred for acute abdominal pain between 2001 and 2007 were included. MR images were retrospectively reviewed and compared with surgical and pathologic findings and clinical follow-up data. Analysis of imaging findings included evaluation of the visceral organs, bowel and mesentery, appendix (for presence of appendicitis), ovaries (detection and adnexal masses were evaluated), focal inflammation, presence of abscesses, and any other abnormal findings.

Results

A total of 118 pregnant patients were included. MR findings were inconclusive in 2 patients and were positive for acute appendicitis in 11 patients (n = 9 confirmed by surgery, n = 2 improved without surgery). One patient with inconclusive MR had surgically confirmed appendicitis; the other patient with inconclusive MR had surgically confirmed adnexal torsion. Other surgical/interventional diagnoses suggested by MR imaging were adnexal torsion (n = 4), abscess (n = 4), acute cholecystitis (n = 1), and gastric volvulus (n = 1). Two patients with MR diagnosis of torsion improved without surgery. One patient with MR diagnosis of abscess had biliary cystadenoma at surgery. The rest of the MR diagnoses above were confirmed surgically or interventionally. MR imaging was normal in 67 patients and demonstrated medically treatable etiology in 28 patients: adnexal lesions (n = 9), urinary pathology (n = 6), cholelithiasis (n = 4), degenerating fibroid (n = 3), DVT (n = 2), hernia (n = 1), colitis (n = 1), thick terminal ileum (n = 1), rectus hematoma (n = 1). Three of these patients had negative surgical exploration and one had adnexal mass excision during pregnancy. Other patients were discharged with medical treatment. The sensitivity, specificity, accuracy, positive predictive values (ppv), and negative predictive values (npv) of MR imaging for acute appendicitis, and surgical/ interventional diagnoses were 90.0% vs. 88.9%, 98.1% vs. 95.0%, 97.5% vs. 94.1%, 81.8% vs. 76.2%, 99.1% vs. 97.9%, respectively.

Conclusion

MR imaging is an excellent modality for diagnosis of acute appendicitis and exclusion of diseases requiring surgical/interventional treatment. Therefore MR imaging is useful for triage of pregnant patients with acute abdominal and pelvic pain.
Literature
1.
go back to reference Cappell MS, Friedel D (2003) Abdominal pain during pregnancy. Gastroenterol Clin North Am 32:1–58PubMedCrossRef Cappell MS, Friedel D (2003) Abdominal pain during pregnancy. Gastroenterol Clin North Am 32:1–58PubMedCrossRef
2.
go back to reference Baer JL, Reis RA, Arens RA (1932) Appendicitis in pregnancy. JAMA 52:1359–1364 Baer JL, Reis RA, Arens RA (1932) Appendicitis in pregnancy. JAMA 52:1359–1364
3.
go back to reference Oto A, Srinivasan PN, Ernst RD, et al. (2006) Revisiting MRI for appendix location during pregnancy. AJR 186:883–887PubMedCrossRef Oto A, Srinivasan PN, Ernst RD, et al. (2006) Revisiting MRI for appendix location during pregnancy. AJR 186:883–887PubMedCrossRef
4.
go back to reference Cobben LP, Groot I, Haans L, et al. (2004) MRI for clinically suspected appendicitis during pregnancy. AJR 183:671–675PubMed Cobben LP, Groot I, Haans L, et al. (2004) MRI for clinically suspected appendicitis during pregnancy. AJR 183:671–675PubMed
5.
go back to reference Birchard KR, Brown MA, Hyslop WB, et al. (2005) MRI of acute adominal and pelvic pain in pregnant patients. AJR 184:452–458PubMed Birchard KR, Brown MA, Hyslop WB, et al. (2005) MRI of acute adominal and pelvic pain in pregnant patients. AJR 184:452–458PubMed
6.
go back to reference Oto A, Ernst RD, Shah R, et al. (2005) Right-lower-quadrant pain and suspected appendicitis in pregnant women: evaluation with MR imaging-initial experience. Radiology 234:445–451PubMedCrossRef Oto A, Ernst RD, Shah R, et al. (2005) Right-lower-quadrant pain and suspected appendicitis in pregnant women: evaluation with MR imaging-initial experience. Radiology 234:445–451PubMedCrossRef
7.
go back to reference Pedrosa I, Levine D, Eyvazzadeh AD, et al. (2006) MR imaging evaluation of acute appendicitis in pregnancy. Radiology 238:891–899PubMedCrossRef Pedrosa I, Levine D, Eyvazzadeh AD, et al. (2006) MR imaging evaluation of acute appendicitis in pregnancy. Radiology 238:891–899PubMedCrossRef
8.
go back to reference Rha SE, Byun JY, Jung SE et al. (2002) CT and MR imaging features of adnexal torsion. RadioGraphics 22:283–294PubMed Rha SE, Byun JY, Jung SE et al. (2002) CT and MR imaging features of adnexal torsion. RadioGraphics 22:283–294PubMed
9.
go back to reference Born C, Wirth S, Stabler A, et al. (2004) Diagnosis of adnexal torsion in the third trimester of pregnancy: a case report. Abdom Imaging 29:123–127PubMedCrossRef Born C, Wirth S, Stabler A, et al. (2004) Diagnosis of adnexal torsion in the third trimester of pregnancy: a case report. Abdom Imaging 29:123–127PubMedCrossRef
10.
go back to reference Spencer JA, Chahal R, Kelly A, et al. (2004) Evaluation of painful hydronephrosis in pregnancy: magnetic resonance urographic patterns in physiological dilatation versus calculous obstruction. J Urol 171:256–260PubMedCrossRef Spencer JA, Chahal R, Kelly A, et al. (2004) Evaluation of painful hydronephrosis in pregnancy: magnetic resonance urographic patterns in physiological dilatation versus calculous obstruction. J Urol 171:256–260PubMedCrossRef
12.
go back to reference Stone K (2002) Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol 45:553–561PubMedCrossRef Stone K (2002) Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol 45:553–561PubMedCrossRef
13.
go back to reference Sharp HT (1994) Gastrointestinal surgical conditions during pregnancy. Clin Obstet Gynecol 37:306–315PubMedCrossRef Sharp HT (1994) Gastrointestinal surgical conditions during pregnancy. Clin Obstet Gynecol 37:306–315PubMedCrossRef
14.
go back to reference Mortele KJ, Ros PR (2001) Cystic focal liver lesions in the adult: differential CT and MR imaging features. Radiographics 21:895–910PubMed Mortele KJ, Ros PR (2001) Cystic focal liver lesions in the adult: differential CT and MR imaging features. Radiographics 21:895–910PubMed
15.
go back to reference Shellock FG, Kanal E (1999) Safety of magnetic resonance imaging contrast agents. J Magn Reson Imaging 10:477–484PubMedCrossRef Shellock FG, Kanal E (1999) Safety of magnetic resonance imaging contrast agents. J Magn Reson Imaging 10:477–484PubMedCrossRef
16.
go back to reference Novak Z, Thurmond AS, Ross PL, et al. (1993) Gadolinium-DTPA transplacental transfer and distribution in fetal tissue in rabbits. Invest Radiol 28:828–830PubMedCrossRef Novak Z, Thurmond AS, Ross PL, et al. (1993) Gadolinium-DTPA transplacental transfer and distribution in fetal tissue in rabbits. Invest Radiol 28:828–830PubMedCrossRef
17.
go back to reference Chapon C, Franconi F, Roux J, et al. (2005) Prenatal evaluation of kidney function in mice using dynamic contrast-enhanced magnetic resonance imaging. Anat Embryol (Berl) 209:263–267CrossRef Chapon C, Franconi F, Roux J, et al. (2005) Prenatal evaluation of kidney function in mice using dynamic contrast-enhanced magnetic resonance imaging. Anat Embryol (Berl) 209:263–267CrossRef
18.
go back to reference Kanal E, Barkovich AJ, Bell C, et al. (2007) ACR guidance document for safe MR practices: 2007. AJR 188:1–27CrossRef Kanal E, Barkovich AJ, Bell C, et al. (2007) ACR guidance document for safe MR practices: 2007. AJR 188:1–27CrossRef
19.
go back to reference Lim HK, Bae SH, Seo GS (1992) Diagnosis of acute appendicitis in pregnant women: value of sonography. AJR 159:539–542PubMed Lim HK, Bae SH, Seo GS (1992) Diagnosis of acute appendicitis in pregnant women: value of sonography. AJR 159:539–542PubMed
20.
go back to reference Barloon TJ, Brown BP, Abu-Yousef MM, et al. (1995) Sonography of acute appendicitis in pregnancy. Abdom Imaging 20:149–151PubMedCrossRef Barloon TJ, Brown BP, Abu-Yousef MM, et al. (1995) Sonography of acute appendicitis in pregnancy. Abdom Imaging 20:149–151PubMedCrossRef
21.
go back to reference Kok RD, de Vries MM, Heerschap A, et al. (2004) Absence of harmful effects of magnetic resonance exposure at 1.5T in utero during the third trimester of pregnancy: a follow-up study. Magn Reson Imaging 22(6):851–854PubMedCrossRef Kok RD, de Vries MM, Heerschap A, et al. (2004) Absence of harmful effects of magnetic resonance exposure at 1.5T in utero during the third trimester of pregnancy: a follow-up study. Magn Reson Imaging 22(6):851–854PubMedCrossRef
22.
go back to reference Baker PN, Johnson IR, Harvey PR, et al. (1994) A three-year follow-up of children imaged in utero with echo-planar magnetic resonance. Am J Obstet Gynecol 170:32–33PubMed Baker PN, Johnson IR, Harvey PR, et al. (1994) A three-year follow-up of children imaged in utero with echo-planar magnetic resonance. Am J Obstet Gynecol 170:32–33PubMed
23.
go back to reference Myers C, Duncan KR, Gowland PA, et al. (1998) Failure to detect intrauterine growth restriction following in utero exposure to MRI. Br J Radiol 71(845):549–551PubMed Myers C, Duncan KR, Gowland PA, et al. (1998) Failure to detect intrauterine growth restriction following in utero exposure to MRI. Br J Radiol 71(845):549–551PubMed
24.
go back to reference Clements H, Duncan KR, Fielding K, et al. (2000) Infants exposed to MRI in utero have a normal paediatric assessment at 9 months of age. Br J Radiol 73(866):190–194PubMed Clements H, Duncan KR, Fielding K, et al. (2000) Infants exposed to MRI in utero have a normal paediatric assessment at 9 months of age. Br J Radiol 73(866):190–194PubMed
25.
go back to reference US Food and Drug Administration (1988) Magnetic resonance diagnostic device: panel recommendation and report on petitions for MR classification. Fed Reg 53:7575–7579 US Food and Drug Administration (1988) Magnetic resonance diagnostic device: panel recommendation and report on petitions for MR classification. Fed Reg 53:7575–7579
26.
go back to reference Kirshenbaum M, Mishra V, Kuo D, et al. (2003) Resolving appendicitis: role of CT. Abdom Imaging 28:276–279PubMedCrossRef Kirshenbaum M, Mishra V, Kuo D, et al. (2003) Resolving appendicitis: role of CT. Abdom Imaging 28:276–279PubMedCrossRef
Metadata
Title
MR imaging in the triage of pregnant patients with acute abdominal and pelvic pain
Authors
Aytekin Oto
Randy D. Ernst
Labib M. Ghulmiyyah
Thomas K. Nishino
Douglas Hughes
Gregory Chaljub
George Saade
Publication date
01-04-2009
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 2/2009
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-008-9381-y

Other articles of this Issue 2/2009

Abdominal Radiology 2/2009 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.