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Published in: Abdominal Radiology 1/2009

01-01-2009

Multi-detector CT in peritoneal carcinomatosis: diagnostic role of thin slices and multiplanar reconstructions

Authors: Tobias Franiel, Gerd Diederichs, Florian Engelken, Thomas Elgeti, Juliane Rost, Patrik Rogalla

Published in: Abdominal Radiology | Issue 1/2009

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Abstract

Background

In order to investigate whether 1-mm thin slices and multiplanar reconstructions (MPRs) of multi-detector computed tomography (CT) datasets interpreted in addition to isotropic 5-mm thick slices in one session improve the detection of peritoneal carcinomatosis.

Methods

The abdominal CT datasets of 44 patients with histologically proven tumors of the abdomen or pelvis were retrospectively evaluated for peritoneal carcinomatosis by four radiologists with variable experience (radiologist 1: ≥10 years, radiologists 2 and 3: 1.5 years, radiologist 4: 0.5 years). In three successive steps, the radiologists evaluated first the axial 5-mm slices, second the 1-mm slices, and third the MPRs and rated their diagnostic confidence.

Results

Specificity was nearly unchanged for all the four radiologists. Sensitivity improved for the most experienced and the least experienced radiologists and was unchanged for the two readers with intermediate skills. Except for the third step of radiologist 4, no statistically significant differences in diagnostic performance were detected. The diagnostic confidence of all the four readers benefited to variable degrees from interpretation of the 1-mm slices and MPRs.

Conclusions

While 5-mm slices are sufficient for the detection of peritoneal carcinomatosis, 1-mm slices and MPRs can improve sensitivity and diagnostic confidence.
Literature
1.
go back to reference Coakley FV, Hricak H (1999) Imaging of peritoneal and mesenteric disease: key concepts for the clinical radiologist. Clin Radiol 54:563–574PubMedCrossRef Coakley FV, Hricak H (1999) Imaging of peritoneal and mesenteric disease: key concepts for the clinical radiologist. Clin Radiol 54:563–574PubMedCrossRef
2.
go back to reference Dähnert W (2003) Gastrointestinal tract. In: Dähnert W (ed) Radiology review manual. Philadelphia: Lippincott Williams & Wilkins, p 852 Dähnert W (2003) Gastrointestinal tract. In: Dähnert W (ed) Radiology review manual. Philadelphia: Lippincott Williams & Wilkins, p 852
3.
go back to reference de Bree E, Koops W, Kroger R, van Ruth S, Witkamp AJ, Zoetmulder FA. (2004) Peritoneal carcinomatosis from colorectal or appendiceal origin: correlation of preoperative CT with intraoperative findings and evaluation of interobserver agreement. J Surg Oncol;86:64–73PubMedCrossRef de Bree E, Koops W, Kroger R, van Ruth S, Witkamp AJ, Zoetmulder FA. (2004) Peritoneal carcinomatosis from colorectal or appendiceal origin: correlation of preoperative CT with intraoperative findings and evaluation of interobserver agreement. J Surg Oncol;86:64–73PubMedCrossRef
4.
go back to reference Scaglione M, Pinto A, Romano S et al (2005) Using multidetector row computed tomography to diagnose and stage pancreatic carcinoma: the problems and the possibilities. JOP 6:1–5PubMed Scaglione M, Pinto A, Romano S et al (2005) Using multidetector row computed tomography to diagnose and stage pancreatic carcinoma: the problems and the possibilities. JOP 6:1–5PubMed
5.
go back to reference Meyers MA (1973) Distribution of intra-abdominal malignant seeding: dependency on dynamics of flow of ascitic fluid. Am J Roentgenol Radium Ther Nucl Med 119:198–206PubMed Meyers MA (1973) Distribution of intra-abdominal malignant seeding: dependency on dynamics of flow of ascitic fluid. Am J Roentgenol Radium Ther Nucl Med 119:198–206PubMed
6.
go back to reference Meyers MA (1981) Intraperitoneal spread of malignancies and its effect on the bowel. Clin Radiol 32:129–146PubMedCrossRef Meyers MA (1981) Intraperitoneal spread of malignancies and its effect on the bowel. Clin Radiol 32:129–146PubMedCrossRef
7.
go back to reference Meyers MA (1994) Intraperitoneal spread of malignancies. In: Meyers MA (ed) Dynamic radiology of the abdomen. New York Berlin Heidelberg London Paris Tokyo: Springer Verlag, pp 115–218 Meyers MA (1994) Intraperitoneal spread of malignancies. In: Meyers MA (ed) Dynamic radiology of the abdomen. New York Berlin Heidelberg London Paris Tokyo: Springer Verlag, pp 115–218
8.
9.
go back to reference Baker AWJ (1993) Treatment of malignant ascites. In: De Vita VT Jr, Hellmann S, Rosenberg SA (eds) Cancer: principles and practice of oncology. Philadelphia: Lippincott, pp 2255–2261 Baker AWJ (1993) Treatment of malignant ascites. In: De Vita VT Jr, Hellmann S, Rosenberg SA (eds) Cancer: principles and practice of oncology. Philadelphia: Lippincott, pp 2255–2261
10.
go back to reference Koppe MJ, Boerman OC, Oyen WJ, Bleichrodt RP (2006) Peritoneal carcinomatosis of colorectal origin: incidence and current treatment strategies. Ann Surg 243:212–222PubMedCrossRef Koppe MJ, Boerman OC, Oyen WJ, Bleichrodt RP (2006) Peritoneal carcinomatosis of colorectal origin: incidence and current treatment strategies. Ann Surg 243:212–222PubMedCrossRef
11.
go back to reference Buy JN, Moss AA, Ghossain MA et al (1988) Peritoneal implants from ovarian tumors: CT findings. Radiology 169:691–694PubMed Buy JN, Moss AA, Ghossain MA et al (1988) Peritoneal implants from ovarian tumors: CT findings. Radiology 169:691–694PubMed
12.
go back to reference Halvorsen RA Jr, Panushka C, Oakley GJ, Letourneau JG, Adcock LL (1991) Intraperitoneal contrast material improves the CT detection of peritoneal metastases. AJR 157:37–40PubMed Halvorsen RA Jr, Panushka C, Oakley GJ, Letourneau JG, Adcock LL (1991) Intraperitoneal contrast material improves the CT detection of peritoneal metastases. AJR 157:37–40PubMed
13.
go back to reference Jacquet P, Jelinek JS, Steves MA, Sugarbaker PH (1993) Evaluation of computed tomography in patients with peritoneal carcinomatosis. Cancer 72:1631–1636PubMedCrossRef Jacquet P, Jelinek JS, Steves MA, Sugarbaker PH (1993) Evaluation of computed tomography in patients with peritoneal carcinomatosis. Cancer 72:1631–1636PubMedCrossRef
14.
go back to reference Coakley FV, Choi PH, Gougoutas CA et al (2002) Peritoneal metastases: detection with spiral CT in patients with ovarian cancer. Radiology 223:495–499PubMedCrossRef Coakley FV, Choi PH, Gougoutas CA et al (2002) Peritoneal metastases: detection with spiral CT in patients with ovarian cancer. Radiology 223:495–499PubMedCrossRef
15.
go back to reference Fultz PJ, Jacobs CV, Hall WJ et al (1999) Ovarian cancer: comparison of observer performance for four methods of interpreting CT scans. Radiology 212:401–410PubMed Fultz PJ, Jacobs CV, Hall WJ et al (1999) Ovarian cancer: comparison of observer performance for four methods of interpreting CT scans. Radiology 212:401–410PubMed
16.
go back to reference Kulinna C, Eibel R, Matzek W et al (2004) Staging of rectal cancer: diagnostic potential of multiplanar reconstructions with MDCT. AJR 183:421–427PubMed Kulinna C, Eibel R, Matzek W et al (2004) Staging of rectal cancer: diagnostic potential of multiplanar reconstructions with MDCT. AJR 183:421–427PubMed
17.
go back to reference Smith SL, Rajan PS (2004) Imaging of pancreatic adenocarcinoma with emphasis on multidetector CT. Clin Radiol 59:26–38PubMedCrossRef Smith SL, Rajan PS (2004) Imaging of pancreatic adenocarcinoma with emphasis on multidetector CT. Clin Radiol 59:26–38PubMedCrossRef
18.
go back to reference Schreyer AG, Scheibl K, Zorger N et al (2005) Detection rate and efficiency of lymph node assessment with axial and coronal image reading based on 16 row multislice CT of the neck. Rofo 177:1430–1435PubMed Schreyer AG, Scheibl K, Zorger N et al (2005) Detection rate and efficiency of lymph node assessment with axial and coronal image reading based on 16 row multislice CT of the neck. Rofo 177:1430–1435PubMed
19.
go back to reference Shimizu K, Ito K, Matsunaga N, Shimizu A, Kawakami Y (2005) Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol 185:1152–1158PubMedCrossRef Shimizu K, Ito K, Matsunaga N, Shimizu A, Kawakami Y (2005) Diagnosis of gastric cancer with MDCT using the water-filling method and multiplanar reconstruction: CT-histologic correlation. AJR Am J Roentgenol 185:1152–1158PubMedCrossRef
20.
go back to reference Pannu HK, Bristow RE, Montz FJ, Fishman EK (2003) Multidetector CT of peritoneal carcinomatosis from ovarian cancer. Radiographics 23:687–701PubMedCrossRef Pannu HK, Bristow RE, Montz FJ, Fishman EK (2003) Multidetector CT of peritoneal carcinomatosis from ovarian cancer. Radiographics 23:687–701PubMedCrossRef
21.
go back to reference Landis JR, Koch GG (1977) An application of hierarchical kappa-type statistics in the assessment of majority agreement among multiple observers. Biometrics 33:363–374PubMedCrossRef Landis JR, Koch GG (1977) An application of hierarchical kappa-type statistics in the assessment of majority agreement among multiple observers. Biometrics 33:363–374PubMedCrossRef
22.
go back to reference Ha HK, Jung JI, Lee MS et al (1996) CT differentiation of tuberculous peritonitis and peritoneal carcinomatosis. AJR 167:743–748PubMed Ha HK, Jung JI, Lee MS et al (1996) CT differentiation of tuberculous peritonitis and peritoneal carcinomatosis. AJR 167:743–748PubMed
23.
go back to reference Rodriguez E, Pombo F (1996) Peritoneal tuberculosis versus peritoneal carcinomatosis: distinction based on CT findings. J Comput Assist Tomogr 20:269–272PubMedCrossRef Rodriguez E, Pombo F (1996) Peritoneal tuberculosis versus peritoneal carcinomatosis: distinction based on CT findings. J Comput Assist Tomogr 20:269–272PubMedCrossRef
24.
go back to reference Fujiyoshi F, Ichinari N, Kajiya Y et al (1997) Retractile mesenteritis: small-bowel radiography, CT, and MR imaging. AJR 169:791–793PubMed Fujiyoshi F, Ichinari N, Kajiya Y et al (1997) Retractile mesenteritis: small-bowel radiography, CT, and MR imaging. AJR 169:791–793PubMed
25.
go back to reference Papadatos D, Taourel P, Bret PM (1996) CT of leiomyomatosis peritonealis disseminata mimicking peritoneal carcinomatosis. AJR 167:475–476PubMed Papadatos D, Taourel P, Bret PM (1996) CT of leiomyomatosis peritonealis disseminata mimicking peritoneal carcinomatosis. AJR 167:475–476PubMed
26.
go back to reference Scott WW Jr, Fishman EK (1990) Extramedullary hematopoiesis mimicking the appearance of carcinomatosis or peritoneal mesothelioma: computed tomography demonstration. Gastrointest Radiol 15:82–83PubMedCrossRef Scott WW Jr, Fishman EK (1990) Extramedullary hematopoiesis mimicking the appearance of carcinomatosis or peritoneal mesothelioma: computed tomography demonstration. Gastrointest Radiol 15:82–83PubMedCrossRef
Metadata
Title
Multi-detector CT in peritoneal carcinomatosis: diagnostic role of thin slices and multiplanar reconstructions
Authors
Tobias Franiel
Gerd Diederichs
Florian Engelken
Thomas Elgeti
Juliane Rost
Patrik Rogalla
Publication date
01-01-2009
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 1/2009
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-008-9372-z

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