Top

European Journal of Nuclear Medicine and Molecular Imaging

Published in:

02-12-2023 | Positron Emission Tomography | Letter to the Editor

Total-body PET/CT or LAFOV PET/CT? Axial field-of-view clinical classification

Authors: Clemens Mingels, Federico Caobelli, Abass Alavi, Christos Sachpekidis, Meiyun Wang, Hande Nalbant, Austin R. Pantel, Hongcheng Shi, Axel Rominger, Lorenzo Nardo

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 4/2024

Excerpt

Dear Sir, …

Phelps ME, Hoffman EJ, Huang SC, Kuhl DE. ECAT: a new computerized tomographic imaging system for positron-emitting radiopharmaceuticals. J Nucl Med: Off Publ, Soc Nucl Med. 1978;19:635–47.

Vandenberghe S, Moskal P, Karp JS. State of the art in total body PET. EJNMMI Physics. 2020;7:35. https://doi.org/10.1186/s40658-020-00290-2.CrossRefPubMedPubMedCentral

Dimitrakopoulou-Strauss A, Pan L, Sachpekidis C. Long axial field of view (LAFOV) PET-CT: implementation in static and dynamic oncological studies. Eur J Nucl Med Mol Imaging. 2023;50:3354–62. https://doi.org/10.1007/s00259-023-06222-3.CrossRefPubMedPubMedCentral

Alberts I, Hünermund J-N, Prenosil G, Mingels C, Bohn KP, Viscione M, et al. Clinical performance of long axial field of view PET/CT: a head-to-head intra-individual comparison of the Biograph Vision Quadra with the Biograph Vision PET/CT. Eur J Nucl Med Mol Imaging. 2021;48:2395–404. https://doi.org/10.1007/s00259-021-05282-7.CrossRefPubMedPubMedCentral

Cherry SR, Jones T, Karp JS, Qi J, Moses WW, Badawi RD. Total-body PET: maximizing Sensitivity to create new opportunities for clinical research and patient care. J Nucl Med: Off Publ, Soc Nucl Med. 2018;59:3–12. https://doi.org/10.2967/jnumed.116.184028.CrossRef

Conti M, Bendriem B, Casey M, Eriksson L, Jakoby B, Jones WF, et al. Performance of a high sensitivity PET scanner based on LSO panel detectors. IEEE Trans Nucl Sci. 2006;53:1136–42. https://doi.org/10.1109/TNS.2006.875153.ADSCrossRef

Watanabe M, Shimizu K, Omura T, Sato N, Takahashi M, Kosugi T, et al. A high-throughput whole-body PET scanner using flat panel PS-PMTs. IEEE Trans Nucl Sci. 2004;51:796–800. https://doi.org/10.1109/TNS.2004.829787.ADSCrossRef

(NCD-RisC) NRFC. 2019. https://ncdrisc.org/data-visualisations-height.html. Accessed 07/10/2023.

Versluys TMM, Foley RA, Skylark WJ. The influence of leg-to-body ratio, arm-to-body ratio and intra-limb ratio on male human attractiveness. R Soc Open Sci. 2018;5: 171790. https://doi.org/10.1098/rsos.171790.ADSCrossRefPubMedPubMedCentral

10.

Dai B, Daube-Witherspoon ME, McDonald S, Werner ME, Parma MJ, Geagan MJ, et al. Performance evaluation of the PennPET explorer with expanded axial coverage. Phys Med Biol. 2023;68. https://doi.org/10.1088/1361-6560/acc722.

11.

Karp JS, Viswanath V, Geagan MJ, Muehllehner G, Pantel AR, Parma MJ, et al. PennPET explorer: design and preliminary performance of a whole-body imager. J Nucl Med : Off Publ, Soc Nucl Med. 2020;61:136–43. https://doi.org/10.2967/jnumed.119.229997.CrossRef

12.

Calderón E, Schmidt FP, Lan W, Castaneda-Vega S, Brendlin AS, Trautwein NF, et al. Image quality and quantitative PET parameters of low-dose [18F]FDG PET in a long axial field-of-view PET/CT scanner. Diagnostics. 2023;13:3240.CrossRefPubMedPubMedCentral

13.

Prenosil GA, Sari H, Fürstner M, Afshar-Oromieh A, Shi K, Rominger A, et al. Performance characteristics of the biograph vision quadra PET/CT system with a long axial field of view using the NEMA NU 2–2018 standard. J Nucl Med : Off Publ, Soc Nucl Med. 2022;63:476–84. https://doi.org/10.2967/jnumed.121.261972.CrossRef

14.

Sachpekidis C, Pan L, Kopp-Schneider A, Weru V, Hassel JC, Dimitrakopoulou-Strauss A. Application of the long axial field-of-view PET/CT with low-dose [18F]FDG in melanoma. Eur J Nucl Med Mol Imaging. 2022. https://doi.org/10.1007/s00259-022-06070-7.CrossRefPubMedPubMedCentral

15.

Roya M, Mostafapour S, Mohr P, Providência L, Li Z, van Snick JH, et al. Current and future use of long axial field-of-view positron emission tomography/computed tomography scanners in clinical oncology. Cancers (Basel). 2023;15(21):5173. https://doi.org/10.3390/cancers15215173.CrossRefPubMedPubMedCentral

16.

Surti S, Pantel AR, Karp JS. Total body PET: why, how, what for? IEEE Trans Radiat Plasma Med Sci. 2020;4:283–92. https://doi.org/10.1109/trpms.2020.2985403.CrossRefPubMedPubMedCentral

17.

Mingels C, Weidner S, Sari H, Buesser D, Zeimpekis K, Shi K, et al. Impact of the new ultra-high sensitivity mode in a long axial field-of-view PET/CT. Ann Nucl Med. 2023. https://doi.org/10.1007/s12149-023-01827-y.CrossRefPubMedPubMedCentral

18.

von Schulthess GK, Steinert HC, Hany TF. Integrated PET/CT: current applications and future directions. Radiology. 2006;238:405–22. https://doi.org/10.1148/radiol.2382041977.CrossRef

19.

Ozdemir S, McCook B, Klassen C. Whole-body versus routine skull base to mid-thigh (18)F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with malignant melanoma. J Clin Imaging Sci. 2020;10:47. https://doi.org/10.25259/jcis_93_2020.CrossRefPubMedPubMedCentral

20.

Badawi RD, Karp JS, Nardo L, Pantel AR. Total body PET: exploring new horizons. PET Clinics. 2021;16:xvii-xviii. https://doi.org/10.1016/j.cpet.2020.09.005.

21.

Lan X, Younis MH, Li K, Cai W. First clinical experience of 106 cm, long axial field-of-view (LAFOV) PET/CT: an elegant balance between standard axial (23 cm) and total-body (194 cm) systems. Eur J Nucl Med Mol Imaging. 2021;48:3755–9. https://doi.org/10.1007/s00259-021-05505-x.CrossRefPubMedPubMedCentral

22.

Nardo L, Pantel AR. Oncologic applications of long axial field-of-view PET/computed tomography. PET Clin. 2021;16:65–73. https://doi.org/10.1016/j.cpet.2020.09.010.CrossRefPubMedPubMedCentral

23.

Nadig V, Herrmann K, Mottaghy FM, Schulz V. Hybrid total-body pet scanners—current status and future perspectives. Eur J Nucl Med Mol Imaging. 2022;49:445–59. https://doi.org/10.1007/s00259-021-05536-4.CrossRefPubMed

Title: Total-body PET/CT or LAFOV PET/CT? Axial field-of-view clinical classification
Authors: Clemens Mingels
Federico Caobelli
Abass Alavi
Christos Sachpekidis
Meiyun Wang
Hande Nalbant
Austin R. Pantel
Hongcheng Shi
Axel Rominger
Lorenzo Nardo
Publication date: 02-12-2023
Publisher: Springer Berlin Heidelberg
Keyword: Positron Emission Tomography
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 4/2024
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-023-06534-4

2024 ASCO Annual Meeting

Springer Medicine

Total-body PET/CT or LAFOV PET/CT? Axial field-of-view clinical classification

Excerpt

2024 ASCO Annual Meeting

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 4/2024

The LUTIA trial: a small step for PRRT, a giant leap for intra-arterial radionuclide therapy trial methodology

An extended bore length solid-state digital-BGO PET/CT system: design, preliminary experience, and performance characteristics

Theragnostic: radiopharmaceuticals and nuclear medicine as viewed through Hegel’s eyes

Early, non-invasive detection of radiation-induced lung injury using PET/CT by targeting CXCR4

Multicentric development and evaluation of [18F]FDG PET/CT and CT radiomic models to predict regional and/or distant recurrence in early-stage non-small cell lung cancer treated by stereotactic body radiation therapy

Intra-arterial peptide-receptor radionuclide therapy for neuro-endocrine tumour liver metastases: an in-patient randomised controlled trial (LUTIA)