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European Journal of Nuclear Medicine and Molecular Imaging

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01-02-2021 | Tuberculosis | Image of the Month

[¹⁸F]FDG and ^[68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions

Authors: Bing Hao, Xiurong Wu, Yizhen Pang, Long Sun, Hua Wu, Weipeng Huang, Haojun Chen

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 2/2021

Excerpt

[⁶⁸Ga]Ga-DOTA-FAPI-04 is a promising PET tracer that allows imaging of various types of cancer with favorable tumor-to-background contrast. Moreover, intense uptake of [⁶⁸Ga]Ga-DOTA-FAPI-04 was also observed in inflammatory disease due to inflammation-induced fibrosis [1‐5]. As such, [⁶⁸Ga]Ga-DOTA-FAPI-04 PET/CT may also be helpful for delineating the lesion extent in disseminated infection. …

Chen H, Pang Y, Wu J, Zhao L, Hao B, Wu J, et al. Comparison of [(68)Ga]Ga-DOTA-FAPI-04 and [(18)F] FDG PET/CT for the diagnosis of primary and metastatic lesions in patients with various types of cancer. Eur J Nucl Med Mol Imaging. 2020. https://doi.org/10.1007/s00259-020-04769-z.

Luo Y, Pan Q, Zhang W. IgG4-related disease revealed by (68)Ga-FAPI and (18)F-FDG PET/CT. Eur J Nucl Med Mol Imaging. 2019;46(12):2625–6. https://doi.org/10.1007/s00259-019-04478-2.CrossRef

Luo Y, Pan Q, Zhang W, Li F. Intense FAPI uptake in inflammation may mask the tumor activity of pancreatic Cancer in 68Ga-FAPI PET/CT. Clin Nucl Med. 2020;45(4):310–1. https://doi.org/10.1097/rlu.0000000000002914.CrossRef

Pang Y, Huang H, Fu L, Zhao L, Chen H. 68Ga-FAPI PET/CT detects gastric signet-ring cell carcinoma in a patient previously treated for prostate Cancer. Clin Nucl Med. 2020. https://doi.org/10.1097/rlu.0000000000003099.

Zhao L, Chen S, Lin L, Sun L, Wu H, Lin Q, et al. [(68)Ga]Ga-DOTA-FAPI-04 improves tumor staging and monitors early response to chemoradiotherapy in a patient with esophageal cancer. Eur J Nucl Med Mol Imaging. 2020. https://doi.org/10.1007/s00259-020-04818-7.

Title: [18F]FDG and [68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions
Authors: Bing Hao
Xiurong Wu
Yizhen Pang
Long Sun
Hua Wu
Weipeng Huang
Haojun Chen
Publication date: 01-02-2021
Publisher: Springer Berlin Heidelberg
Keywords: Tuberculosis
Mycobacterium Tuberculosis
Tuberculosis
Back Pain
Back Pain
Back Pain
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 2/2021
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-020-04941-5

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[¹⁸F]FDG and ^[68Ga]Ga-DOTA-FAPI-04 PET/CT in the evaluation of tuberculous lesions

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