Top

European Journal of Nuclear Medicine and Molecular Imaging

Published in:

01-12-2012 | Editorial

Nuclear cardiology at the door of a new era: better to save mSv or to reduce imaging time?

Authors: Assuero Giorgetti, Dario Genovesi, Paolo Marzullo

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 12/2012

Excerpt

The evolution of nuclear cardiology has gone through several clinical protocols that can be summarized as ²⁰¹Tl stress/redistribution, ²⁰¹Tl stress/redistribution with delayed imaging, ²⁰¹Tl stress/redistribution with reinjection, single- or double-day ^99mTc-labelled radiotracers, and ²⁰¹Tl/^99mTc combined approaches. This evolution covered more or less 30 years with a significant (at least 25 %) increase in the accuracy of the method, but (up to few years ago) a decrease in the mSv to the patient of less than 5 %. Recent advances in hardware and software applied to nuclear cardiology [1] have led to short imaging times and/or low-dose studies, but the choice of the best combination is still difficult. …

Garcia EV, Faber TL, Esteves FP. Cardiac dedicated ultrafast SPECT cameras: new designs and clinical implications. J Nucl Med. 2011;52:210–7.PubMedCrossRef

Picano E. The risks of inappropriateness in cardiac imaging. Int J Environ Res Public Health. 2009;6:1649–64.PubMedCrossRef

IMV. 2003 nuclear medicine census market summary report. Des Plaines, IL: IMV Medical Information Division.

Slomka PJ, Patton JA, Berman DS, Germano G. Advances in technical aspects of myocardial perfusion SPECT imaging. J Nucl Cardiol. 2009;16:255–76.PubMedCrossRef

Herzog BA, Buechel RR, Katz R, Pazhenkottil A, Valenta I, Gaemperli O, et al. Nuclear myocardial perfusion imaging with a cadmium-zinc-telluride detector technique: optimized protocol for scan time reduction. J Nucl Med. 2010;51:46–51.PubMedCrossRef

Duvall WL, Croft LB, Ginsberg ES, Einstein AJ, Guma KA, George T, et al. Reduced isotope dose and imaging time with a high-efficiency CZT SPECT camera. J Nucl Cardiol. 2011;18:847–57.PubMedCrossRef

Gimelli A, Bottai M, Genovesi D, Giorgetti A, Di Martino F, Marzullo P. High diagnostic accuracy of low-dose gated-SPECT with solid-state ultrafast detectors: preliminary clinical results. Eur J Nucl Med Mol Imaging. 2012;39(1):83–90.PubMedCrossRef

Gimelli A, Bottai M, Giorgetti A, Genovesi D, Filidei E, Marzullo P. Evaluation of ischaemia in obese patients: feasibility and accuracy of a low-dose protocol with a cadmium-zinc telluride camera. Eur J Nucl Med Mol Imaging. 2012;39(8):1254–61.PubMedCrossRef

Nkoulou R, Pazhenkottil AP, Kuest SM, Ghadri JR, Wolfrum M, Husmann L, et al. Semiconductor detectors allow low-dose–low-dose 1-day SPECT myocardial perfusion imaging. J Nucl Med. 2011;52(8):1204–9.PubMedCrossRef

10.

Nakazato R, Tamarappoo BK, Kang X, Wolak A, Kite F, Hayes SW, et al. Quantitative upright-supine high-speed SPECT myocardial perfusion imaging for detection of coronary artery disease: correlation with invasive coronary angiography. J Nucl Med. 2010;51(11):1724–31.PubMedCrossRef

11.

Pazhenkottil AP, Herzog BA, Husmann L, Buechel RR, Burger IA, Valenta I, et al. Non-invasive assessment of coronary artery disease with CT coronary angiography and SPECT: a novel dose-saving fast-track algorithm. Eur J Nucl Med Mol Imaging. 2010;37:522–7.PubMedCrossRef

Title: Nuclear cardiology at the door of a new era: better to save mSv or to reduce imaging time?
Authors: Assuero Giorgetti
Dario Genovesi
Paolo Marzullo
Publication date: 01-12-2012
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 12/2012
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-012-2238-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Nuclear cardiology at the door of a new era: better to save mSv or to reduce imaging time?

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Issue 12/2012

Quantitative longitudinal interrelationships between brain metabolism and amyloid deposition during a 2-year follow-up in patients with early Alzheimer’s disease

Early FDG PET response assessment of preoperative radiochemotherapy in locally advanced rectal cancer: correlation with long-term outcome

Stress-induced myocardial ischemia is associated with early post-stress left ventricular mechanical dyssynchrony as assessed by phase analysis of 201Tl gated SPECT myocardial perfusion imaging

SPECT/CT arthrography of the knee

Biokinetics and dosimetry of 111In-DOTA-NOC-ATE compared with 111In-DTPA-octreotide

Association of primary tumour FDG uptake with clinical, histopathological and molecular characteristics in breast cancer patients scheduled for neoadjuvant chemotherapy