Published in:
01-09-2013 | Case Report
Case report: imaging features in a renal transplant patient with calcineurin inhibitor-induced pain syndrome (CIPS)
Authors:
Russell W. Chapin, Elizabeth Chua, Jennifer Simmons, Martin Bunke
Published in:
Skeletal Radiology
|
Issue 9/2013
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Abstract
Post-transplant distal limb bone marrow edema syndrome or calcineurin inhibitor-induced pain syndrome (CIPS) is generally a self-limiting but debilitating acute pain syndrome that has been reported in 2–14 % of renal transplant recipients. The disease is extensively described in the transplant literature in patients receiving the calcineurin inhibitors cyclosporine and tacrolimus. We present a case of CIPS arising in a patient 73 days after renal allograft, review the imaging findings, and discuss proposed etiologies and differential diagnoses. To the authors’ knowledge, CIPS has not been characterized as a distinct entity in the radiology literature.