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Skeletal Radiology
Published in: Skeletal Radiology 5/2009

01-05-2009 | Review Article

Bone marrow edema syndrome

Authors: Anastasios V. Korompilias, Apostolos H. Karantanas, Marios G. Lykissas, Alexandros E. Beris

Published in: Skeletal Radiology | Issue 5/2009

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Abstract

Bone marrow edema syndrome (BMES) refers to transient clinical conditions with unknown pathogenic mechanism, such as transient osteoporosis of the hip (TOH), regional migratory osteoporosis (RMO), and reflex sympathetic dystrophy (RSD). BMES is primarily characterized by bone marrow edema (BME) pattern. The disease mainly affects the hip, the knee, and the ankle of middle-aged males. Many hypotheses have been proposed to explain the pathogenesis of the disease. Unfortunately, the etiology of BMES remains obscure. The hallmark that separates BMES from other conditions presented with BME pattern is its self-limited nature. Laboratory tests usually do not contribute to the diagnosis. Histological examination of the lesion is unnecessary. Plain radiographs may reveal regional osseous demineralization. Magnetic resonance imaging is mainly used for the early diagnosis and monitoring the progression of the disease. Early differentiation from other aggressive conditions with long-term sequelae is essential in order to avoid unnecessary treatment. Clinical entities, such as TOH, RMO, and RSD are spontaneously resolving, and surgical treatment is not needed. On the other hand, early differential diagnosis and surgical treatment in case of osteonecrosis is of crucial importance.
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Metadata
Title
Bone marrow edema syndrome
Authors
Anastasios V. Korompilias
Apostolos H. Karantanas
Marios G. Lykissas
Alexandros E. Beris
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
Skeletal Radiology / Issue 5/2009
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-008-0529-1

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