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01-01-2007 | Case Report

Synovial sarcoma of primary bone origin: a rare case in a rare site with atypical features

Authors: Seung Chai Jung, Jung-Ah Choi, Jin-Haeng Chung, Joo Han Oh, Joon Woo Lee, Heung Sik Kang

Published in: Skeletal Radiology | Issue 1/2007

Abstract

Synovial sarcoma of bone origin is extremely rare and difficult to diagnose. We present a case in which the lesion arose in the cortex of the distal tibia. It showed heterogeneous intermediate signal intensity on T1-weighted images and heterogeneous intermediate to low signal intensity on T2-weighted images with heterogeneous contrast enhancement on MRI. The lesion was confirmed as synovial sarcoma using a combination of histological and molecular genetic studies.

Raney RB. Synovial sarcoma in young people: background, prognostic factors, and therapeutic questions. J Pediatr Hematol Oncol 2005;27:207–211PubMedCrossRef

Hiraga H, Nojima T, Isu K, Yamashiro K, Yamawaki S, Nagashima K. Histological and molecular evidence of synovial sarcoma of bone. A case report. J Bone Jt Surg Am 1999;81:558–563

O’Donnell P, Diss TC, Whelan J, Flanagan AM. Synovial sarcoma with radiological appearances of primitive neuroectodermal tumour/Ewing sarcoma: differentiation by molecular genetic studies. Skeletal Radiol 2005;12:1–7

Nakajo M, Ohkubo K, Nandate T, et al. Primary synovial sarcoma of the sternum: computed tomography and magnetic resonance imaging findings. Radiat Med 2005;23:208–212PubMed

Cohen IJ, Issakov J, Avigad S, et al. Synovial sarcoma of bone delineated by spectral karyotyping. Lancet 1997;350:1679–1680PubMedCrossRef

Tilakaratne WM. Synovial sarcoma of the mandible. J Oral Pathol Med 2006;35:61–63PubMedCrossRef

Sar C, Eralp L. Surgical treatment of primary tumors of the sacrum. Arch Orthop Trauma Surg 2002;122:148–155PubMedCrossRef

Scully SP, Temple HT, Harrelson JM. Synovial sarcoma of the foot and ankle. Clin Orthop Relat Res 1999;364:220–226PubMedCrossRef

Valenzuela RF, Kim EE, Seo JG, Patel S, Yasko AW. A revisit of MRI analysis for synovial sarcoma. Clin Imaging 2000;24:231–235PubMedCrossRef

10.

Jones BC, Sundaram M, Kransdorf MJ. Synovial sarcoma: MR imaging findings in 34 patients. AJR Am J Roentgenol 1993;161:827–830PubMed

11.

Coindre JM, Pelmus M, Hostein I, Lussan C, Bui BN, Guillou L. Should molecular testing be required for diagnosing synovial sarcoma? A prospective study of 204 cases. Cancer 2003;98:2700–2707PubMedCrossRef

12.

Turc-Carel C, Dal Cin P, Limon J, et al. Involvement of chromosome X in primary cytogenetic change in human neoplasia: nonrandom translocation in synovial sarcoma. Proc Natl Acad Sci USA 1987;84:1981–1985PubMedCrossRef

13.

Tvrdik D, Povysil C, Svatosova J, Dundr P. Molecular diagnosis of synovial sarcoma: RT-PCR detection of SYT-SSX1/2 fusion transcripts in paraffin-embedded tissue. Med Sci Monit 2005;11:MT1–MT7PubMed

Title: Synovial sarcoma of primary bone origin: a rare case in a rare site with atypical features
Authors: Seung Chai Jung
Jung-Ah Choi
Jin-Haeng Chung
Joo Han Oh
Joon Woo Lee
Heung Sik Kang
Publication date: 01-01-2007
Publisher: Springer-Verlag
Published in: Skeletal Radiology / Issue 1/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-006-0185-2

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Synovial sarcoma of primary bone origin: a rare case in a rare site with atypical features

Abstract

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Abstract

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