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Pediatric Radiology
Published in: Pediatric Radiology 8/2013

01-08-2013 | Original Article

MRI features of atypical teratoid/rhabdoid tumors in children

Authors: Biao Jin, Xiao Yuan Feng

Published in: Pediatric Radiology | Issue 8/2013

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Abstract

Background

Atypical teratoid/rhabdoid tumors (AT/RTs) are rare, highly malignant tumors of the central nervous system, usually occurring in young children.

Objective

To investigate the MRI features of AT/RT, with special emphasis on diffusion-weighted imaging (DWI) and MR spectroscopy (MRS).

Materials and methods

MRI findings of 11 children with AT/RT were reviewed retrospectively, including DWI in 9 AT/RT children and MRS in 6 children.

Results

The neoplasms were infratentorial in 4 children and supratentorial in 5 children, both infra- and supratentorial in 1 child and multifocal in 1 child. AT/RT produced heterogeneous signal intensity from peripheral cysts in 7/11 (63%) and hemorrhage in 7/11 (63%). All lesions showed contrast enhancement of varying degrees. Seven (63%) had peritumoral edema. Nine (82%) were hyperintense on DWI with a mean ± SD ADC of 0.60 ± 0.13 × 10−3 mm2 s−1. Six lesions (55%) exhibited elevated levels of choline and decreased NAA, and three had lipid peaks.

Conclusions

A childhood intracranial tumor with off-midline location, peripheral cystic components, hemorrhage, low ADC, and lipid peaks on MRS suggests AT/RT to be considered a differential diagnosis.
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Metadata
Title
MRI features of atypical teratoid/rhabdoid tumors in children
Authors
Biao Jin
Xiao Yuan Feng
Publication date
01-08-2013
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 8/2013
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-013-2646-9

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