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Published in: Pediatric Radiology 6/2008

Open Access 01-06-2008 | Review

Imaging findings in noncraniofacial childhood rhabdomyosarcoma

Authors: Rick R. Van Rijn, Jim C. H. Wilde, Johannes Bras, Foppe Oldenburger, Kieran M. C. McHugh, Johannes H. M. Merks

Published in: Pediatric Radiology | Issue 6/2008

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Abstract

Rhabdomyosarcoma (RMS) is the most common soft-tissue sarcoma of childhood. This paper is focuses on imaging for diagnosis, staging, and follow-up of noncraniofacial RMS.
Literature
1.
go back to reference Miller RW, Young JL Jr, Novakovic B (1995) Childhood cancer. Cancer 75(1 Suppl):395–405PubMed Miller RW, Young JL Jr, Novakovic B (1995) Childhood cancer. Cancer 75(1 Suppl):395–405PubMed
2.
go back to reference Stiller CA, Parking DM (1994) International variations in the incidence of childhood soft-tissue sarcomas. Paediatr Perinat Epidemiol 8:107–119PubMedCrossRef Stiller CA, Parking DM (1994) International variations in the incidence of childhood soft-tissue sarcomas. Paediatr Perinat Epidemiol 8:107–119PubMedCrossRef
3.
go back to reference Brisse H, McHugh K, Scaramuzza D (2005) RMS and non-RMS soft tissue sarcomas. Radiological guidelines. In: EpSSG RMS and NRSTS therapeutic protocols Brisse H, McHugh K, Scaramuzza D (2005) RMS and non-RMS soft tissue sarcomas. Radiological guidelines. In: EpSSG RMS and NRSTS therapeutic protocols
4.
go back to reference Weiss SW, Goldblum JR (2001) Enzinger and Weiss’s soft tissue tumors. Mosby, St. Louis, pp 785–836 Weiss SW, Goldblum JR (2001) Enzinger and Weiss’s soft tissue tumors. Mosby, St. Louis, pp 785–836
5.
go back to reference Fletcher CD, Unni KK, Mertens F (2002) WHO classification of tumours: pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon Fletcher CD, Unni KK, Mertens F (2002) WHO classification of tumours: pathology and genetics of tumours of soft tissue and bone. IARC Press, Lyon
6.
go back to reference Cavazzana AQ, Schmidt D, Nifo V et al (1992) Spindle cell rhabdomyosarcoma. A prognostic favourable variant of rhabdomyosarcoma. Am J Surg Pathol 16:229–235PubMed Cavazzana AQ, Schmidt D, Nifo V et al (1992) Spindle cell rhabdomyosarcoma. A prognostic favourable variant of rhabdomyosarcoma. Am J Surg Pathol 16:229–235PubMed
7.
go back to reference Leuschner I, Newton WA Jr, Schmidt D et al (1993) Spindle cell variants of embryonal rhabdomyosarcoma in the paratesticular region. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 17:221–230PubMed Leuschner I, Newton WA Jr, Schmidt D et al (1993) Spindle cell variants of embryonal rhabdomyosarcoma in the paratesticular region. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 17:221–230PubMed
8.
go back to reference Sorensen PH, Lynch JC, Qualman SJ et al (2002) PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children’s oncology group. J Clin Oncol 20:2672–2679PubMed Sorensen PH, Lynch JC, Qualman SJ et al (2002) PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children’s oncology group. J Clin Oncol 20:2672–2679PubMed
9.
go back to reference Kodet R, Newton WA Jr, Hamoudi AB et al (1991) Rhabdomyosarcomas with intermediate-filament inclusions and features of rhabdoid tumors. Light microscopic and immunohistochemical study. Am J Surg Pathol 15:257–267PubMed Kodet R, Newton WA Jr, Hamoudi AB et al (1991) Rhabdomyosarcomas with intermediate-filament inclusions and features of rhabdoid tumors. Light microscopic and immunohistochemical study. Am J Surg Pathol 15:257–267PubMed
10.
go back to reference Kodet R, Newton WA Jr, Hamoudi AB et al (1993) Childhood rhabdomyosarcoma with anaplastic (pleomorphic) features. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 17:443–453PubMedCrossRef Kodet R, Newton WA Jr, Hamoudi AB et al (1993) Childhood rhabdomyosarcoma with anaplastic (pleomorphic) features. A report of the Intergroup Rhabdomyosarcoma Study. Am J Surg Pathol 17:443–453PubMedCrossRef
11.
go back to reference Folpe AL, McKenney JK, Bridge JA et al (2002) Sclerosing rhabdomyosarcoma in adults: report of four cases of a hyalinizing, matrix-rich variant of rhabdomyosarcoma that may be confused with osteosarcoma, chondrosarcoma, or angiosarcoma. Am J Surg Pathol 26:1175–1183PubMed Folpe AL, McKenney JK, Bridge JA et al (2002) Sclerosing rhabdomyosarcoma in adults: report of four cases of a hyalinizing, matrix-rich variant of rhabdomyosarcoma that may be confused with osteosarcoma, chondrosarcoma, or angiosarcoma. Am J Surg Pathol 26:1175–1183PubMed
12.
go back to reference Newton WA Jr, Gehan EA, Webber BL et al (1995) Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification – an Intergroup Rhabdomyosarcoma study. Cancer 76:1073–1085PubMed Newton WA Jr, Gehan EA, Webber BL et al (1995) Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification – an Intergroup Rhabdomyosarcoma study. Cancer 76:1073–1085PubMed
13.
go back to reference Sebire NJ, Roebuck DJ (2006) Pathological diagnosis of paediatric tumours from image-guided needle core biopsies: a systematic review. Pediatr Radiol 36:426–431PubMed Sebire NJ, Roebuck DJ (2006) Pathological diagnosis of paediatric tumours from image-guided needle core biopsies: a systematic review. Pediatr Radiol 36:426–431PubMed
14.
go back to reference Paterson A, Frush DP, Donnelly L (2001) Helical CT of the body: are settings adjusted for pediatric patients? AJR 176:297–301PubMed Paterson A, Frush DP, Donnelly L (2001) Helical CT of the body: are settings adjusted for pediatric patients? AJR 176:297–301PubMed
15.
go back to reference Brenner DJ, Elliston CD, Hall EJ et al (2001) Estimated risks of radiation induced fatal cancer from pediatric CT. AJR 176:289–296PubMed Brenner DJ, Elliston CD, Hall EJ et al (2001) Estimated risks of radiation induced fatal cancer from pediatric CT. AJR 176:289–296PubMed
16.
go back to reference Kim EE, Valenzuela RF, Kumar AJ et al (2000) Imaging and clinical spectrum of rhabdomyosarcoma in children. Clin Imaging 24:257–262PubMed Kim EE, Valenzuela RF, Kumar AJ et al (2000) Imaging and clinical spectrum of rhabdomyosarcoma in children. Clin Imaging 24:257–262PubMed
17.
go back to reference Enneking WF, Spanier SS, Goodman MA (2003) The classic – a system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res 415:4–18PubMed Enneking WF, Spanier SS, Goodman MA (2003) The classic – a system for the surgical staging of musculoskeletal sarcoma. Clin Orthop Relat Res 415:4–18PubMed
18.
go back to reference Goo HW, Choi SH, Ghim T et al (2005) Whole-body MRI of paediatric malignant tumours: comparison with conventional oncological imaging methods. Pediatr Radiol 35:766–773PubMed Goo HW, Choi SH, Ghim T et al (2005) Whole-body MRI of paediatric malignant tumours: comparison with conventional oncological imaging methods. Pediatr Radiol 35:766–773PubMed
19.
go back to reference Drup-Link HE, Franzius C, Link TM et al (2001) Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. AJR 177:229–236 Drup-Link HE, Franzius C, Link TM et al (2001) Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. AJR 177:229–236
20.
go back to reference Cogswell A, Howman-Giles R, Bergin M (1994) Bone and gallium scintigraphy in children with rhabdomyosarcoma: a 10-year review. Med Pediatr Oncol 22:15–21PubMed Cogswell A, Howman-Giles R, Bergin M (1994) Bone and gallium scintigraphy in children with rhabdomyosarcoma: a 10-year review. Med Pediatr Oncol 22:15–21PubMed
21.
go back to reference Jager PL, Hoekstra HJ, Leeuw J et al (2000) Routine bone scintigraphy in primary staging of soft tissue sarcoma; is it worthwhile? Cancer 89:1726–1731PubMed Jager PL, Hoekstra HJ, Leeuw J et al (2000) Routine bone scintigraphy in primary staging of soft tissue sarcoma; is it worthwhile? Cancer 89:1726–1731PubMed
22.
go back to reference Jadvar H, Connolly LP, Fahey FH (2007) PET and PET/CT in pediatric oncology. Semin Nucl Med 37:316–331PubMed Jadvar H, Connolly LP, Fahey FH (2007) PET and PET/CT in pediatric oncology. Semin Nucl Med 37:316–331PubMed
23.
go back to reference Ben Arush MW, Bar SR, Postovsky S et al (2006) Assessing the use of FDG-PET in the detection of regional and metastatic nodes in alveolar rhabdomyosarcoma of extremities. J Pediatr Hematol Oncol 28:440–445PubMed Ben Arush MW, Bar SR, Postovsky S et al (2006) Assessing the use of FDG-PET in the detection of regional and metastatic nodes in alveolar rhabdomyosarcoma of extremities. J Pediatr Hematol Oncol 28:440–445PubMed
24.
go back to reference McCarville MB, Christie R, Daw NC et al (2005) PET/CT in the evaluation of childhood sarcomas. AJR 184:1293–1304PubMed McCarville MB, Christie R, Daw NC et al (2005) PET/CT in the evaluation of childhood sarcomas. AJR 184:1293–1304PubMed
25.
go back to reference Stevens MC, Rey A, Bouvet N et al (2005) Treatment of nonmetastatic rhabdomyosarcoma in childhood and adolescence: third study of the International Society of Paediatric Oncology – SIOP Malignant Mesenchymal Tumor 89. J Clin Oncol 23:2618–2628PubMed Stevens MC, Rey A, Bouvet N et al (2005) Treatment of nonmetastatic rhabdomyosarcoma in childhood and adolescence: third study of the International Society of Paediatric Oncology – SIOP Malignant Mesenchymal Tumor 89. J Clin Oncol 23:2618–2628PubMed
26.
go back to reference Carli M, Colombatti R, Oberlin O et al (2004) European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors. J Clin Oncol 22:4787–4794PubMed Carli M, Colombatti R, Oberlin O et al (2004) European intergroup studies (MMT4-89 and MMT4-91) on childhood metastatic rhabdomyosarcoma: final results and analysis of prognostic factors. J Clin Oncol 22:4787–4794PubMed
27.
go back to reference Klijanienko J, Caillaud JM, Orbach D et al (2007) Cyto-histological correlations in primary, recurrent and metastatic rhabdomyosarcoma: the Institut Curie’s experience. Diagn Cytopathol 35:482–487PubMed Klijanienko J, Caillaud JM, Orbach D et al (2007) Cyto-histological correlations in primary, recurrent and metastatic rhabdomyosarcoma: the Institut Curie’s experience. Diagn Cytopathol 35:482–487PubMed
28.
go back to reference Bisogno G, Bergeron C, Jenney M et al (2005) EpSSG RMS 2005; a protocol for non metastatic rhabdomyosarcoma. 1 June 2005, Padova Bisogno G, Bergeron C, Jenney M et al (2005) EpSSG RMS 2005; a protocol for non metastatic rhabdomyosarcoma. 1 June 2005, Padova
29.
go back to reference Therasse P, Arbuck SG, Eisenhauer EA et al (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205–216PubMed Therasse P, Arbuck SG, Eisenhauer EA et al (2000) New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 92:205–216PubMed
30.
go back to reference McHugh K, Kao S (2003) Can paediatric radiologists resist RECIST (response evaluation criteria in solid tumours)? Pediatr Radiol 33:739–743PubMed McHugh K, Kao S (2003) Can paediatric radiologists resist RECIST (response evaluation criteria in solid tumours)? Pediatr Radiol 33:739–743PubMed
31.
go back to reference Barnacle AM, McHugh K (2006) Limitations with the response evaluation criteria in solid tumors (RECIST) guidance in disseminated pediatric malignancy. Pediatr Blood Cancer 46:127–134PubMed Barnacle AM, McHugh K (2006) Limitations with the response evaluation criteria in solid tumors (RECIST) guidance in disseminated pediatric malignancy. Pediatr Blood Cancer 46:127–134PubMed
32.
go back to reference Pappo AS, Anderson JR, Crist WM et al (1999) Survival after relapse in children and adolescents with rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Study Group. J Clin Oncol 17:3487–3493PubMed Pappo AS, Anderson JR, Crist WM et al (1999) Survival after relapse in children and adolescents with rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Study Group. J Clin Oncol 17:3487–3493PubMed
33.
go back to reference Peng F, Rabkin G, Muzik O (2006) Use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography to monitor therapeutic response by rhabdomyosarcoma in children: report of a retrospective case study. Clin Nucl Med 31:394–397PubMed Peng F, Rabkin G, Muzik O (2006) Use of 2-deoxy-2-[F-18]-fluoro-D-glucose positron emission tomography to monitor therapeutic response by rhabdomyosarcoma in children: report of a retrospective case study. Clin Nucl Med 31:394–397PubMed
34.
go back to reference Castellino SM, McLean TW (2007) Pediatric genitourinary tumors. Curr Opin Oncol 19:248–253PubMed Castellino SM, McLean TW (2007) Pediatric genitourinary tumors. Curr Opin Oncol 19:248–253PubMed
35.
go back to reference Agrons GA, Wagner BJ, Lonergan GJ et al (1997) From the archives of the AFIP. Genitourinary rhabdomyosarcoma in children: radiologic-pathologic correlation. Radiographics 17:919–937PubMed Agrons GA, Wagner BJ, Lonergan GJ et al (1997) From the archives of the AFIP. Genitourinary rhabdomyosarcoma in children: radiologic-pathologic correlation. Radiographics 17:919–937PubMed
36.
go back to reference Mak CW, Chou CK, Su CC et al (2004) Ultrasound diagnosis of paratesticular rhabdomyosarcoma. Br J Radiol 77:250–252PubMed Mak CW, Chou CK, Su CC et al (2004) Ultrasound diagnosis of paratesticular rhabdomyosarcoma. Br J Radiol 77:250–252PubMed
37.
go back to reference Sanghvi DA, Purandare NC, Jambhekar NA et al (2004) Primary rhabdomyosarcoma of the seminal vesicle. Br J Radiol 77:159–160PubMed Sanghvi DA, Purandare NC, Jambhekar NA et al (2004) Primary rhabdomyosarcoma of the seminal vesicle. Br J Radiol 77:159–160PubMed
38.
go back to reference Moroni M, Nesi G, Travaglini F et al (2003) Rhabdomyosarcoma of the spermatic cord. A case report with review of the literature. Urol Int 71:114–117PubMed Moroni M, Nesi G, Travaglini F et al (2003) Rhabdomyosarcoma of the spermatic cord. A case report with review of the literature. Urol Int 71:114–117PubMed
39.
go back to reference Ciftci AO, Bingol-Kologlu M, Senocak ME et al (2001) Testicular tumors in children. J Pediatr Surg 36:1796–1801PubMed Ciftci AO, Bingol-Kologlu M, Senocak ME et al (2001) Testicular tumors in children. J Pediatr Surg 36:1796–1801PubMed
40.
go back to reference Solomon LA, Zurawin RK, Edwards CL (2003) Vaginoscopic resection for rhabdomyosarcoma of the vagina: a case report and review of the literature. J Pediatr Adolesc Gynecol 16:139–142PubMed Solomon LA, Zurawin RK, Edwards CL (2003) Vaginoscopic resection for rhabdomyosarcoma of the vagina: a case report and review of the literature. J Pediatr Adolesc Gynecol 16:139–142PubMed
41.
go back to reference Martelli H, Oberlin O, Rey A et al (1999) Conservative treatment for girls with nonmetastatic rhabdomyosarcoma of the genital tract: a report from the Study Committee of the International Society of Pediatric Oncology. J Clin Oncol 17:2117–2122PubMed Martelli H, Oberlin O, Rey A et al (1999) Conservative treatment for girls with nonmetastatic rhabdomyosarcoma of the genital tract: a report from the Study Committee of the International Society of Pediatric Oncology. J Clin Oncol 17:2117–2122PubMed
42.
go back to reference Arul GS, Porter H, Spicer RD (2000) Nonrhabdomyosarcomatous botyroid tumour of the cervix uteri: is it a new entity? Med Pediatr Oncol 35:147–149PubMed Arul GS, Porter H, Spicer RD (2000) Nonrhabdomyosarcomatous botyroid tumour of the cervix uteri: is it a new entity? Med Pediatr Oncol 35:147–149PubMed
43.
go back to reference Lowry DL, Guido RS (2000) The vulvar mass in the prepubertal child. J Pediatr Adolesc Gynecol 13:75–78PubMed Lowry DL, Guido RS (2000) The vulvar mass in the prepubertal child. J Pediatr Adolesc Gynecol 13:75–78PubMed
44.
go back to reference Bond SJ, Seibel N, Kapur S et al (1994) Rhabdomyosarcoma of the clitoris. Cancer 73:1984–1986PubMed Bond SJ, Seibel N, Kapur S et al (1994) Rhabdomyosarcoma of the clitoris. Cancer 73:1984–1986PubMed
45.
go back to reference Chan YF, Leung CS, Ma L (1989) Primary embryonal rhabdomyosarcoma of the ovary in a 4-year-old girl. Histopathology 15:309–311PubMed Chan YF, Leung CS, Ma L (1989) Primary embryonal rhabdomyosarcoma of the ovary in a 4-year-old girl. Histopathology 15:309–311PubMed
46.
go back to reference Montag TW, D’ablaing G, Schlaerth JB et al (1986) Embryonal rhabdomyosarcoma of the uterine corpus and cervix. Gynecol Oncol 25:171–194PubMed Montag TW, D’ablaing G, Schlaerth JB et al (1986) Embryonal rhabdomyosarcoma of the uterine corpus and cervix. Gynecol Oncol 25:171–194PubMed
47.
go back to reference Hays DM, Raney RB Jr, Lawrence W Jr et al (1981) Rhabdomyosarcoma of the female urogenital tract. J Pediatr Surg 16:828–834PubMed Hays DM, Raney RB Jr, Lawrence W Jr et al (1981) Rhabdomyosarcoma of the female urogenital tract. J Pediatr Surg 16:828–834PubMed
48.
go back to reference Ghushe ND, Drugas GT (2007) Rhabdomyosarcoma of the clitoris. Pediatr Radiol 37:1179PubMed Ghushe ND, Drugas GT (2007) Rhabdomyosarcoma of the clitoris. Pediatr Radiol 37:1179PubMed
49.
go back to reference McHugh K, Boothroyd AE (1999) The role of radiology in childhood rhabdomyosarcoma. Clin Radiol 54:2–10PubMed McHugh K, Boothroyd AE (1999) The role of radiology in childhood rhabdomyosarcoma. Clin Radiol 54:2–10PubMed
50.
go back to reference Heyn R, Newton WA, Raney RB et al (1997) Preservation of the bladder in patients with rhabdomyosarcoma. J Clin Oncol 15:69–75PubMed Heyn R, Newton WA, Raney RB et al (1997) Preservation of the bladder in patients with rhabdomyosarcoma. J Clin Oncol 15:69–75PubMed
51.
go back to reference Miller DV, Coffin CM, Zhou H (2004) Rhabdomyosarcoma arising in the hand or foot: a clinicopathologic analysis. Pediatr Dev Pathol 7:361–369PubMed Miller DV, Coffin CM, Zhou H (2004) Rhabdomyosarcoma arising in the hand or foot: a clinicopathologic analysis. Pediatr Dev Pathol 7:361–369PubMed
52.
go back to reference Rao BN, Rodriguez-Galindo C (2003) Local control in childhood extremity sarcomas: salvaging limbs and sparing function. Med Pediatr Oncol 41:584–587PubMed Rao BN, Rodriguez-Galindo C (2003) Local control in childhood extremity sarcomas: salvaging limbs and sparing function. Med Pediatr Oncol 41:584–587PubMed
53.
go back to reference Breneman JC, Wiener ES (2000) Issues in the local control of rhabdomyosarcoma. Med Pediatr Oncol 35:104–109PubMed Breneman JC, Wiener ES (2000) Issues in the local control of rhabdomyosarcoma. Med Pediatr Oncol 35:104–109PubMed
54.
go back to reference Andrassy RJ, Wiener ES, Raney RB et al (1998) Thoracic sarcomas in children. Ann Surg 227:170–173PubMed Andrassy RJ, Wiener ES, Raney RB et al (1998) Thoracic sarcomas in children. Ann Surg 227:170–173PubMed
55.
go back to reference Soyer T, Karnak I, Ciftci AO et al (2006) The results of surgical treatment of chest wall tumors in childhood. Pediatr Surg Int 22:135–139PubMed Soyer T, Karnak I, Ciftci AO et al (2006) The results of surgical treatment of chest wall tumors in childhood. Pediatr Surg Int 22:135–139PubMed
56.
57.
go back to reference Saenz NC, Ghavimi F, Gerald W et al (1997) Chest wall rhabdomyosarcoma. Cancer 80:1513–1517PubMed Saenz NC, Ghavimi F, Gerald W et al (1997) Chest wall rhabdomyosarcoma. Cancer 80:1513–1517PubMed
58.
go back to reference Doladzas T, Arvelakis A, Karavokyros IG et al (2005) Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation. Pediatr Hematol Oncol 22:525–529PubMed Doladzas T, Arvelakis A, Karavokyros IG et al (2005) Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation. Pediatr Hematol Oncol 22:525–529PubMed
59.
go back to reference Ozcan C, Celik A, Ural Z et al (2001) Primary pulmonary rhabdomyosarcoma arising within cystic adenomatoid malformation: a case report and review of the literature. J Pediatr Surg 36:1062–1065PubMed Ozcan C, Celik A, Ural Z et al (2001) Primary pulmonary rhabdomyosarcoma arising within cystic adenomatoid malformation: a case report and review of the literature. J Pediatr Surg 36:1062–1065PubMed
60.
go back to reference West D, Nicholson AG, Colquhoun I et al (2007) Bronchioloalveolar carcinoma in congenital cystic adenomatoid malformation of lung. Ann Thorac Surg 83:687–689PubMed West D, Nicholson AG, Colquhoun I et al (2007) Bronchioloalveolar carcinoma in congenital cystic adenomatoid malformation of lung. Ann Thorac Surg 83:687–689PubMed
61.
go back to reference Pai S, Eng HL, Lee SY et al (2007) Correction: pleuropulmonary blastoma, not rhabdomyosarcoma in a congenital lung cyst. Pediatr Blood Cancer 48:370–371PubMed Pai S, Eng HL, Lee SY et al (2007) Correction: pleuropulmonary blastoma, not rhabdomyosarcoma in a congenital lung cyst. Pediatr Blood Cancer 48:370–371PubMed
62.
go back to reference d’Agostino S, Bonoldi E, Dante S et al (1997) Embryonal rhabdomyosarcoma of the lung arising in cystic adenomatoid malformation: case report and review of the literature. J Pediatr Surg 32:1381–1383PubMed d’Agostino S, Bonoldi E, Dante S et al (1997) Embryonal rhabdomyosarcoma of the lung arising in cystic adenomatoid malformation: case report and review of the literature. J Pediatr Surg 32:1381–1383PubMed
63.
go back to reference Priest JR, Hill AD, Williams GM (2006) Type I pleuropulmonary blastoma: a report from the international pleuropulmonary blastoma registry. J Clin Oncol 24:4492–4498PubMed Priest JR, Hill AD, Williams GM (2006) Type I pleuropulmonary blastoma: a report from the international pleuropulmonary blastoma registry. J Clin Oncol 24:4492–4498PubMed
64.
go back to reference Granata C, Gambini C, Balducci T et al (1998) Bronchioloalveolar carcinoma arising in congenital cystic adenomatoid malformation in a child: a case report and review on malignancies originating in congenital cystic adenomatoid malformation. Pediatr Pulmonol 25:62–66PubMed Granata C, Gambini C, Balducci T et al (1998) Bronchioloalveolar carcinoma arising in congenital cystic adenomatoid malformation in a child: a case report and review on malignancies originating in congenital cystic adenomatoid malformation. Pediatr Pulmonol 25:62–66PubMed
65.
go back to reference Sauvat F, Michel JL, Benachi A et al (2003) Management of asymptomatic neonatal cystic adenomatoid malformations. J Pediatr Surg 38:548–552PubMed Sauvat F, Michel JL, Benachi A et al (2003) Management of asymptomatic neonatal cystic adenomatoid malformations. J Pediatr Surg 38:548–552PubMed
66.
go back to reference Roebuck DJ, Yang WT, Lam WW et al (1998) Hepatobiliary rhabdomyosarcoma in children: diagnostic radiology. Pediatr Radiol 28:101–108PubMed Roebuck DJ, Yang WT, Lam WW et al (1998) Hepatobiliary rhabdomyosarcoma in children: diagnostic radiology. Pediatr Radiol 28:101–108PubMed
67.
go back to reference Spunt SL, Lobe TE, Pappo AS et al (2000) Aggressive surgery is unwarranted for biliary tract rhabdomyosarcoma. J Pediatr Surg 35:309–316PubMed Spunt SL, Lobe TE, Pappo AS et al (2000) Aggressive surgery is unwarranted for biliary tract rhabdomyosarcoma. J Pediatr Surg 35:309–316PubMed
68.
go back to reference Hill DA, Dehner LP, Gow KW et al (2002) Perianal rhabdomyosarcoma presenting as a perirectal abscess: a report of 11 cases. J Pediatr Surg 37:576–581PubMed Hill DA, Dehner LP, Gow KW et al (2002) Perianal rhabdomyosarcoma presenting as a perirectal abscess: a report of 11 cases. J Pediatr Surg 37:576–581PubMed
69.
go back to reference Caty MG, Oldham KT, Prochownik EV (1990) Embryonal rhabdomyosarcoma of the ampulla of Vater with long-term survival following pancreaticoduodenectomy. J Pediatr Surg 25:1256–1258PubMed Caty MG, Oldham KT, Prochownik EV (1990) Embryonal rhabdomyosarcoma of the ampulla of Vater with long-term survival following pancreaticoduodenectomy. J Pediatr Surg 25:1256–1258PubMed
70.
go back to reference Chung CJ, Fordham L, Little S et al (1998) Intraperitoneal rhabdomyosarcoma in children: incidence and imaging characteristics on CT. AJR 170:1385–1387PubMed Chung CJ, Fordham L, Little S et al (1998) Intraperitoneal rhabdomyosarcoma in children: incidence and imaging characteristics on CT. AJR 170:1385–1387PubMed
71.
go back to reference Odim J, Reehal V, Laks H et al (2003) Surgical pathology of cardiac tumors. Two decades at an urban institution. Cardiovasc Pathol 12:267–270PubMed Odim J, Reehal V, Laks H et al (2003) Surgical pathology of cardiac tumors. Two decades at an urban institution. Cardiovasc Pathol 12:267–270PubMed
72.
go back to reference Aksoylar S, Kansoy S, Bakiler AR et al (2002) Primary cardiac rhabdomyosarcoma. Med Pediatr Oncol 38:146PubMed Aksoylar S, Kansoy S, Bakiler AR et al (2002) Primary cardiac rhabdomyosarcoma. Med Pediatr Oncol 38:146PubMed
73.
go back to reference Raney RB, Anderson JR, Andrassy RJ et al (2000) Soft-tissue sarcomas of the diaphragm: a report from the Intergroup Rhabdomyosarcoma Study Group from 1972 to 1997. J Pediatr Hematol Oncol 22:510–514PubMed Raney RB, Anderson JR, Andrassy RJ et al (2000) Soft-tissue sarcomas of the diaphragm: a report from the Intergroup Rhabdomyosarcoma Study Group from 1972 to 1997. J Pediatr Hematol Oncol 22:510–514PubMed
74.
go back to reference Gupta AK, Mitra DK, Berry M (1999) Primary embryonal rhabdomyosarcoma of the diaphragm in a child: case report. Pediatr Radiol 29:823–825PubMed Gupta AK, Mitra DK, Berry M (1999) Primary embryonal rhabdomyosarcoma of the diaphragm in a child: case report. Pediatr Radiol 29:823–825PubMed
75.
go back to reference Medeiros CW, Kondo W, Baptista I Jr et al (2002) Primary rhabdomyosarcoma of the diaphragm: case report and literature review. Rev Hosp Clin Fac Med Sao Paulo 57:67–72PubMed Medeiros CW, Kondo W, Baptista I Jr et al (2002) Primary rhabdomyosarcoma of the diaphragm: case report and literature review. Rev Hosp Clin Fac Med Sao Paulo 57:67–72PubMed
76.
go back to reference Yokoyama S, Hayashida Y, Nagahama J et al (1997) Rhabdomyosarcoma of the urachus. A case report. Acta Cytol 41(4 Suppl):1293–1298PubMed Yokoyama S, Hayashida Y, Nagahama J et al (1997) Rhabdomyosarcoma of the urachus. A case report. Acta Cytol 41(4 Suppl):1293–1298PubMed
77.
go back to reference Brecher AR, Reyes-Mugica M, Kamino H et al (2003) Congenital primary cutaneous rhabdomyosarcoma in a neonate. Pediatr Dermatol 20:335–338PubMed Brecher AR, Reyes-Mugica M, Kamino H et al (2003) Congenital primary cutaneous rhabdomyosarcoma in a neonate. Pediatr Dermatol 20:335–338PubMed
78.
go back to reference Matsunaga GS, Shanberg AM, Rajpoot D (2003) Prenatal ultrasonographic detection of bladder rhabdomyosarcoma. J Urol 169:1495–1496PubMed Matsunaga GS, Shanberg AM, Rajpoot D (2003) Prenatal ultrasonographic detection of bladder rhabdomyosarcoma. J Urol 169:1495–1496PubMed
79.
go back to reference Grundy R, Anderson J, Gaze M et al (2001) Congenital alveolar rhabdomyosarcoma: clinical and molecular distinction from alveolar rhabdomyosarcoma in older children. Cancer 91:606–612PubMed Grundy R, Anderson J, Gaze M et al (2001) Congenital alveolar rhabdomyosarcoma: clinical and molecular distinction from alveolar rhabdomyosarcoma in older children. Cancer 91:606–612PubMed
80.
go back to reference Ahmed OA, Hussain A, King DJ et al (1999) Congenital rhabdomyosarcoma. Br J Plast Surg 52:304–307PubMed Ahmed OA, Hussain A, King DJ et al (1999) Congenital rhabdomyosarcoma. Br J Plast Surg 52:304–307PubMed
81.
go back to reference White FV, Dehner LP, Belchis DA et al (1999) Congenital disseminated malignant rhabdoid tumor: a distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11. Am J Surg Pathol 23:249–256PubMed White FV, Dehner LP, Belchis DA et al (1999) Congenital disseminated malignant rhabdoid tumor: a distinct clinicopathologic entity demonstrating abnormalities of chromosome 22q11. Am J Surg Pathol 23:249–256PubMed
82.
go back to reference Orbach D, Rey A, Oberlin O et al (2005) Soft tissue sarcoma or malignant mesenchymal tumors in the first year of life: experience of the International Society of Pediatric Oncology (SIOP) Malignant Mesenchymal Tumor Committee. J Clin Oncol 23:4363–4371PubMed Orbach D, Rey A, Oberlin O et al (2005) Soft tissue sarcoma or malignant mesenchymal tumors in the first year of life: experience of the International Society of Pediatric Oncology (SIOP) Malignant Mesenchymal Tumor Committee. J Clin Oncol 23:4363–4371PubMed
83.
go back to reference Hulse N, Raja S, Kumar A et al (2006) Rhabdomyosarcoma of the extremities in adults. Acta Orthop Belg 72:199–203PubMed Hulse N, Raja S, Kumar A et al (2006) Rhabdomyosarcoma of the extremities in adults. Acta Orthop Belg 72:199–203PubMed
84.
go back to reference Parham DM, Ellison DA (2006) Rhabdomyosarcomas in adults and children: an update. Arch Pathol Lab Med 130:1454–1465PubMed Parham DM, Ellison DA (2006) Rhabdomyosarcomas in adults and children: an update. Arch Pathol Lab Med 130:1454–1465PubMed
85.
go back to reference Ferrari A, Dileo P, Casanova M et al (2003) Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 98:571–580PubMed Ferrari A, Dileo P, Casanova M et al (2003) Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 98:571–580PubMed
86.
go back to reference Allen SD, Moskovic EC, Fisher C et al (2007) Adult rhabdomyosarcoma: cross-sectional imaging findings including histopathologic correlation. AJR 189:371–377PubMed Allen SD, Moskovic EC, Fisher C et al (2007) Adult rhabdomyosarcoma: cross-sectional imaging findings including histopathologic correlation. AJR 189:371–377PubMed
87.
go back to reference Crist WM, Anderson JR, Meza JL et al (2001) Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J Clin Oncol 19:3091–3102PubMed Crist WM, Anderson JR, Meza JL et al (2001) Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease. J Clin Oncol 19:3091–3102PubMed
88.
go back to reference Crist W, Gehan EA, Ragab AH et al (1995) The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 13:610–630PubMed Crist W, Gehan EA, Ragab AH et al (1995) The Third Intergroup Rhabdomyosarcoma Study. J Clin Oncol 13:610–630PubMed
89.
go back to reference Oberlin O, Rey A, Anderson J et al (2001) Treatment of orbital rhabdomyosarcoma: survival and late effects of treatment – results of an international workshop. J Clin Oncol 19:197–204PubMed Oberlin O, Rey A, Anderson J et al (2001) Treatment of orbital rhabdomyosarcoma: survival and late effects of treatment – results of an international workshop. J Clin Oncol 19:197–204PubMed
90.
go back to reference Donaldson SS, Anderson JR (2005) Rhabdomyosarcoma: many similarities, a few philosophical differences. J Clin Oncol 23:2586–2587PubMed Donaldson SS, Anderson JR (2005) Rhabdomyosarcoma: many similarities, a few philosophical differences. J Clin Oncol 23:2586–2587PubMed
91.
go back to reference Scaradavou A, Heller G, Sklar CA et al (1995) Second malignant neoplasms in long-term survivors of childhood rhabdomyosarcoma. Cancer 76:1860–1867PubMed Scaradavou A, Heller G, Sklar CA et al (1995) Second malignant neoplasms in long-term survivors of childhood rhabdomyosarcoma. Cancer 76:1860–1867PubMed
92.
go back to reference Kalapurakal JA, Thomas PR (1997) Pediatric radiotherapy. An overview. Radiol Clin North Am 35:1265–1280PubMed Kalapurakal JA, Thomas PR (1997) Pediatric radiotherapy. An overview. Radiol Clin North Am 35:1265–1280PubMed
93.
go back to reference Stevens MC (2005) Treatment for childhood rhabdomyosarcoma: the cost of cure. Lancet Oncol 6:77–84PubMed Stevens MC (2005) Treatment for childhood rhabdomyosarcoma: the cost of cure. Lancet Oncol 6:77–84PubMed
94.
go back to reference Paulino AC (2004) Late effects of radiotherapy for pediatric extremity sarcomas. Int J Radiat Oncol Biol Phys 60:265–274PubMed Paulino AC (2004) Late effects of radiotherapy for pediatric extremity sarcomas. Int J Radiat Oncol Biol Phys 60:265–274PubMed
95.
go back to reference Spunt SL, Sweeney TA, Hudxon MM et al (2005) Late effects of pelvic rhabdomyosarcoma and its treatment in female survivors. J Clin Oncol 23:7143–7151PubMed Spunt SL, Sweeney TA, Hudxon MM et al (2005) Late effects of pelvic rhabdomyosarcoma and its treatment in female survivors. J Clin Oncol 23:7143–7151PubMed
96.
go back to reference Geenen MM, Cardous-Ubbink MC, Kremer LC et al (2007) Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA 297:2705–2715PubMed Geenen MM, Cardous-Ubbink MC, Kremer LC et al (2007) Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. JAMA 297:2705–2715PubMed
97.
go back to reference Raney B, Anderson J, Jenney M et al (2006) Late effects in 164 patients with rhabdomyosarcoma of the bladder/prostate region: a report from the international workshop. J Urol 176:2190–2194PubMed Raney B, Anderson J, Jenney M et al (2006) Late effects in 164 patients with rhabdomyosarcoma of the bladder/prostate region: a report from the international workshop. J Urol 176:2190–2194PubMed
98.
go back to reference Anderson J, Gordon A, Pritchard-Jones K et al (1999) Genes, chromosomes, and rhabdomyosarcoma. Genes Chromosomes Cancer 26:275–285PubMed Anderson J, Gordon A, Pritchard-Jones K et al (1999) Genes, chromosomes, and rhabdomyosarcoma. Genes Chromosomes Cancer 26:275–285PubMed
99.
go back to reference Flamant F, Rodary C, Voute PA et al (1985) Primary chemotherapy in the treatment of rhabdomyosarcoma in children: trial of the International Society of Pediatric Oncology (SIOP) preliminary results. Radiother Oncol 3:227–236PubMed Flamant F, Rodary C, Voute PA et al (1985) Primary chemotherapy in the treatment of rhabdomyosarcoma in children: trial of the International Society of Pediatric Oncology (SIOP) preliminary results. Radiother Oncol 3:227–236PubMed
100.
go back to reference Flamant F, Gerbaulet A, Nihoul-Fekete C et al (1990) Long-term sequelae of conservative treatment by surgery, brachytherapy, and chemotherapy for vulval and vaginal rhabdomyosarcoma in children. J Clin Oncol 8:1847–1853PubMed Flamant F, Gerbaulet A, Nihoul-Fekete C et al (1990) Long-term sequelae of conservative treatment by surgery, brachytherapy, and chemotherapy for vulval and vaginal rhabdomyosarcoma in children. J Clin Oncol 8:1847–1853PubMed
101.
go back to reference Maurer HM, Crist W, Lawrence W et al (1988) The intergroup rhabdomyosarcoma study-I. A final report. Cancer 61:209–220PubMed Maurer HM, Crist W, Lawrence W et al (1988) The intergroup rhabdomyosarcoma study-I. A final report. Cancer 61:209–220PubMed
102.
go back to reference Maurer HM, Gehan EA, Beltangady M et al (1993) The Intergroup Rhabdomyosarcoma Study-II. Cancer 71:1904–1922PubMed Maurer HM, Gehan EA, Beltangady M et al (1993) The Intergroup Rhabdomyosarcoma Study-II. Cancer 71:1904–1922PubMed
103.
go back to reference Wolden SL, Anderson JR, Crist WM et al (1999) Indications for radiotherapy and chemotherapy after complete resection in rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Studies I to III. J Clin Oncol 17:3468–3475PubMed Wolden SL, Anderson JR, Crist WM et al (1999) Indications for radiotherapy and chemotherapy after complete resection in rhabdomyosarcoma: a report from the Intergroup Rhabdomyosarcoma Studies I to III. J Clin Oncol 17:3468–3475PubMed
104.
go back to reference Schuck A, Mattke AC, Schmidt B et al (2004) Group II rhabdomyosarcoma and rhabdomyosarcomalike tumors: is radiotherapy necessary? J Clin Oncol 22:143–149PubMed Schuck A, Mattke AC, Schmidt B et al (2004) Group II rhabdomyosarcoma and rhabdomyosarcomalike tumors: is radiotherapy necessary? J Clin Oncol 22:143–149PubMed
105.
go back to reference Breneman JC, Lyden E, Pappo AS et al (2003) Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma – a report from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol 21:78–84PubMed Breneman JC, Lyden E, Pappo AS et al (2003) Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma – a report from the Intergroup Rhabdomyosarcoma Study IV. J Clin Oncol 21:78–84PubMed
106.
go back to reference Koscielniak E, Harms D, Henze G et al (1999) Results of treatment for soft tissue sarcoma in childhood and adolescence: a final report of the German Cooperative Soft Tissue Sarcoma Study CWS-86. J Clin Oncol 17:3706–3719PubMed Koscielniak E, Harms D, Henze G et al (1999) Results of treatment for soft tissue sarcoma in childhood and adolescence: a final report of the German Cooperative Soft Tissue Sarcoma Study CWS-86. J Clin Oncol 17:3706–3719PubMed
107.
go back to reference Stewart RJ, Martelli H, Oberlin O et al (2003) Treatment of children with nonmetastatic paratesticular rhabdomyosarcoma: results of the Malignant Mesenchymal Tumors studies (MMT 84 and MMT 89) of the International Society of Pediatric Oncology. J Clin Oncol 21:793–798PubMed Stewart RJ, Martelli H, Oberlin O et al (2003) Treatment of children with nonmetastatic paratesticular rhabdomyosarcoma: results of the Malignant Mesenchymal Tumors studies (MMT 84 and MMT 89) of the International Society of Pediatric Oncology. J Clin Oncol 21:793–798PubMed
108.
go back to reference Buwalda J, Schouwenburg PF, Blank LE et al (2003) A novel local treatment strategy for advanced stage head and neck rhabdomyosarcomas in children: results of the AMORE protocol. Eur J Cancer 39:1594–1602PubMed Buwalda J, Schouwenburg PF, Blank LE et al (2003) A novel local treatment strategy for advanced stage head and neck rhabdomyosarcomas in children: results of the AMORE protocol. Eur J Cancer 39:1594–1602PubMed
109.
go back to reference Haie-Meder C, Flamant F, Revillon Y et al (1994) The role of brachytherapy in the therapeutic strategy of vesico-prostatic rhabdomyosarcoma in children. Ann Urol (Paris) 28:302–305 Haie-Meder C, Flamant F, Revillon Y et al (1994) The role of brachytherapy in the therapeutic strategy of vesico-prostatic rhabdomyosarcoma in children. Ann Urol (Paris) 28:302–305
110.
go back to reference Magne N, Haie-Meder C (2007) Brachytherapy for genital-tract rhabdomyosarcomas in girls: technical aspects, reports, and perspectives. Lancet Oncol 8:725–729PubMed Magne N, Haie-Meder C (2007) Brachytherapy for genital-tract rhabdomyosarcomas in girls: technical aspects, reports, and perspectives. Lancet Oncol 8:725–729PubMed
111.
go back to reference Merchant TE, Parsh N, del Valle PL et al (2000) Brachytherapy for pediatric soft-tissue sarcoma. Int J Radiat Oncol Biol Phys 46:427–432PubMed Merchant TE, Parsh N, del Valle PL et al (2000) Brachytherapy for pediatric soft-tissue sarcoma. Int J Radiat Oncol Biol Phys 46:427–432PubMed
112.
go back to reference Timmermann B, Schuck A, Niggli F et al (2007) Spot-scanning proton therapy for malignant soft tissue tumors in childhood: first experiences at the Paul Scherrer Institute. Int J Radiat Oncol Biol Phys 67:497–504PubMed Timmermann B, Schuck A, Niggli F et al (2007) Spot-scanning proton therapy for malignant soft tissue tumors in childhood: first experiences at the Paul Scherrer Institute. Int J Radiat Oncol Biol Phys 67:497–504PubMed
113.
go back to reference Wolden SL, Wexler LH, Kraus DH et al (2005) Intensity-modulated radiotherapy for head-and-neck rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 61:1432–1438PubMed Wolden SL, Wexler LH, Kraus DH et al (2005) Intensity-modulated radiotherapy for head-and-neck rhabdomyosarcoma. Int J Radiat Oncol Biol Phys 61:1432–1438PubMed
114.
go back to reference Vanel D, Shapeero LG, De Baere T et al (1994) MR imaging in the follow-up of malignant and aggressive soft-tissue tumors: results of 511 examinations. Radiology 190:263–268PubMed Vanel D, Shapeero LG, De Baere T et al (1994) MR imaging in the follow-up of malignant and aggressive soft-tissue tumors: results of 511 examinations. Radiology 190:263–268PubMed
Metadata
Title
Imaging findings in noncraniofacial childhood rhabdomyosarcoma
Authors
Rick R. Van Rijn
Jim C. H. Wilde
Johannes Bras
Foppe Oldenburger
Kieran M. C. McHugh
Johannes H. M. Merks
Publication date
01-06-2008
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 6/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-008-0751-y

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