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Pediatric Radiology
Published in: Pediatric Radiology 6/2008

01-06-2008 | Case Report

Testicular microlithiasis in siblings: clinical implications

Authors: Dimitrios Thomas, Elpis Vlachopapadopoulou, Vassilios Papadakis, Regina Sklavou, Kalliope Stefanaki, Sofia Polychronopoulou, Stefanos Michalacos

Published in: Pediatric Radiology | Issue 6/2008

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Abstract

Testicular microlithiasis is a relatively uncommon condition in children. It is characterized by the presence of microcalcifications within the testicular parenchyma. Although it is a benign finding, underlying diseases and other conditions must be ruled out because testicular microlithiasis has been found in association with both benign and malignant lesions in the testes and other tissues. We present two brothers with testicular microlithiasis, and highlight the prevalence, natural history, associated malignant conditions and follow-up recommendations of children diagnosed with testicular microlithiasis.
Literature
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Miller FN, Sidhu PS (2002) Does testicular microlithiasis matter? A review. Clin Radiol 57:883–890PubMedCrossRef
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Kocaoglu M, Bozlar U, Bulakbasi N et al (2005) Testicular microlithiasis in pediatric age group: ultrasonography findings and literature review. Diag Interv Radiol 11:60–65
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Coffey J, Huddart RA, Elliott F et al (2007) Testicular microlithiasis as a familial risk factor for testicular germ cell tumour. Br J Cancer 97:1701–1706PubMedCrossRef
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Rapley EA, Crockford GP, Easton DF et al (2003) Localization of susceptibility genes for familial testicular germ cell tumour. APMIS 111:128–133PubMedCrossRef
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von der Maase H, Rørth M, Walbom-Jørgensen S et al (1986) Carcinoma in situ of contralateral testis in patients with testicular germ cell cancer: study of 27 cases in 500 patients. Br Med J 293:1398–1401CrossRef
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Corut A, Senyigit A, Ugur SA et al (2006) Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis. Am J Hum Genet 79:650–656PubMedCrossRef
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Campagnoli MF, Pucci A, Garelli E et al (2006) Familial tumoral calcinosis and testicular microlithiasis associated with a new mutation of GALNT3 of a white family. J Clin Pathol 59:440–444PubMedCrossRef
Metadata
Title
Testicular microlithiasis in siblings: clinical implications
Authors
Dimitrios Thomas
Elpis Vlachopapadopoulou
Vassilios Papadakis
Regina Sklavou
Kalliope Stefanaki
Sofia Polychronopoulou
Stefanos Michalacos
Publication date
01-06-2008
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 6/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-008-0749-5

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