Skip to main content
Top
Published in: Pediatric Cardiology 2/2011

01-02-2011 | Original Article

Underrecognition of Elevated Blood Pressure Readings in Children After Early Repair of Coarctation of the Aorta

Authors: Christopher Gillett, Amos Wong, Dirk G. Wilson, Andrew R. Wolf, Robin P. Martin, Damien Kenny

Published in: Pediatric Cardiology | Issue 2/2011

Login to get access

Abstract

Hypertension after repair of coarctation of the aorta (CoA) is the outcome variable most closely associated with adverse long-term events such as stroke and myocardial infarction. This study sought to evaluate the outpatient management of casual blood pressure (BP) measurements in young children after early repair of CoA. A retrospective analysis was performed of clinical findings, echocardiographic data, casual BP recordings, and subsequent BP management of 114 children with CoA repair aged 1–13 years during 338 outpatient visits managed at two congenital cardiac centers. Children with associated significant congenital heart disease or corrective surgery after the age of 6 months were excluded from the study. Blood pressure was documented at 233 clinic visits (69%), and systolic BP (SBP) was above 95th percentile for age and sex in 45 instances (19%). This represented an elevated SBP recording for 31 children (27%), with two or more successive elevated recordings for 11 children (10%). Of 12 subjects receiving antihypertensive medication, three had inadequate BP control. Blood pressure is not documented at approximately 30% of outpatient visits of children with repaired CoA. When elevated BP is documented, in all cases no recorded action was taken. This may have significant implications for cardiovascular outcomes in this cohort of patients.
Literature
1.
go back to reference Tabbutt S, Nicolson SC, Dominguez TE, Wells W, Backer CL, Tweddell JS, Bokesch P, Schreiner M (2008) Perioperative course in 118 infants and children undergoing coarctation repair via a thoracotomy: a prospective, multicenter experience. J Thorac Cardiovasc Surg 136:1229–1236CrossRefPubMed Tabbutt S, Nicolson SC, Dominguez TE, Wells W, Backer CL, Tweddell JS, Bokesch P, Schreiner M (2008) Perioperative course in 118 infants and children undergoing coarctation repair via a thoracotomy: a prospective, multicenter experience. J Thorac Cardiovasc Surg 136:1229–1236CrossRefPubMed
2.
go back to reference Celermajer DS, Greaves K (2002) Survivors of coarctation repair: fixed but not cured. Heart 88:113–114CrossRefPubMed Celermajer DS, Greaves K (2002) Survivors of coarctation repair: fixed but not cured. Heart 88:113–114CrossRefPubMed
3.
go back to reference Cohen M, Fuster V, Steele PM, Driscoll D, McGoon DC (1989) Coarctation of the aorta: long-term follow-up and prediction of outcome after surgical-correction. Circulation 80:840–845PubMed Cohen M, Fuster V, Steele PM, Driscoll D, McGoon DC (1989) Coarctation of the aorta: long-term follow-up and prediction of outcome after surgical-correction. Circulation 80:840–845PubMed
4.
go back to reference de Divitiis M, Rubba P, Calabro R (2005) Arterial hypertension and cardiovascular prognosis after successful repair of aortic coarctation: a clinical model for the study of vascular function. Nutrition Metab Cardiovasc Dis 15:382–394CrossRef de Divitiis M, Rubba P, Calabro R (2005) Arterial hypertension and cardiovascular prognosis after successful repair of aortic coarctation: a clinical model for the study of vascular function. Nutrition Metab Cardiovasc Dis 15:382–394CrossRef
5.
go back to reference Hager A, Kanz S, Kaemmerer H, Schreiber C, Hess J (2007) Coarctation long-term assessment (COALA): significance of arterial hypertension in a cohort of 404 patients up to 27 years after surgical repair of isolated coarctation of the aorta, even in the absence of restenosis and prosthetic material. J Thorac Cardiovasc Surg 134:738–745CrossRefPubMed Hager A, Kanz S, Kaemmerer H, Schreiber C, Hess J (2007) Coarctation long-term assessment (COALA): significance of arterial hypertension in a cohort of 404 patients up to 27 years after surgical repair of isolated coarctation of the aorta, even in the absence of restenosis and prosthetic material. J Thorac Cardiovasc Surg 134:738–745CrossRefPubMed
6.
go back to reference de Divitiis M, Pilla C, Kattenhorn M, Zadinello M, Donald A, Leeson P, Wallace S, Redington A, Deanfield JE (2001) Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery. Circulation 104:I165–I170PubMed de Divitiis M, Pilla C, Kattenhorn M, Zadinello M, Donald A, Leeson P, Wallace S, Redington A, Deanfield JE (2001) Vascular dysfunction after repair of coarctation of the aorta: impact of early surgery. Circulation 104:I165–I170PubMed
7.
go back to reference Ginghina C, Ghiorghiu I, Iancu M, Rica O, Serban M, Platon P, Lupescu I (2007) Predictive factors for the systemic hypertension evolution after repair of coarctation of the aorta. J Hyperten 25:S185 Ginghina C, Ghiorghiu I, Iancu M, Rica O, Serban M, Platon P, Lupescu I (2007) Predictive factors for the systemic hypertension evolution after repair of coarctation of the aorta. J Hyperten 25:S185
8.
go back to reference O’Sullivan JJ, Derrick G, Darnell R (2002) Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24-hour blood pressure measurement. Heart 88:163–166CrossRefPubMed O’Sullivan JJ, Derrick G, Darnell R (2002) Prevalence of hypertension in children after early repair of coarctation of the aorta: a cohort study using casual and 24-hour blood pressure measurement. Heart 88:163–166CrossRefPubMed
9.
go back to reference Daniels SR (2001) Repair of coarctation of the aorta and hypertension: does age matter? Lancet 358:89CrossRefPubMed Daniels SR (2001) Repair of coarctation of the aorta and hypertension: does age matter? Lancet 358:89CrossRefPubMed
10.
go back to reference Roccella EJ (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555–576CrossRef Roccella EJ (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555–576CrossRef
11.
go back to reference Hansen ML, Gunn PW, Kaelber DC (2007) Underdiagnosis of hypertension in children and adolescents. J Am Med Assoc 298:874–879CrossRef Hansen ML, Gunn PW, Kaelber DC (2007) Underdiagnosis of hypertension in children and adolescents. J Am Med Assoc 298:874–879CrossRef
12.
go back to reference Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, Mahoney L, McCrindle B, Mietus-Snyder M, Steinberger J, Daniels S (2008) Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young and the Council for High Blood Pressure Research. Hypertension 52:433–451 Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, Mahoney L, McCrindle B, Mietus-Snyder M, Steinberger J, Daniels S (2008) Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment: a scientific statement from the American Heart Association Atherosclerosis, Hypertension, and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young and the Council for High Blood Pressure Research. Hypertension 52:433–451
13.
go back to reference Kenny D, Polson JW, Martin RP, Wilson DG, Caputo M, Cockcroft JR, Paton JF, Wolf AR (2010) Surgical approach for aortic coarctation influences arterial compliance and blood pressure control. Ann Thorac Surg 90:600–604CrossRefPubMed Kenny D, Polson JW, Martin RP, Wilson DG, Caputo M, Cockcroft JR, Paton JF, Wolf AR (2010) Surgical approach for aortic coarctation influences arterial compliance and blood pressure control. Ann Thorac Surg 90:600–604CrossRefPubMed
Metadata
Title
Underrecognition of Elevated Blood Pressure Readings in Children After Early Repair of Coarctation of the Aorta
Authors
Christopher Gillett
Amos Wong
Dirk G. Wilson
Andrew R. Wolf
Robin P. Martin
Damien Kenny
Publication date
01-02-2011
Publisher
Springer-Verlag
Published in
Pediatric Cardiology / Issue 2/2011
Print ISSN: 0172-0643
Electronic ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-010-9860-0

Other articles of this Issue 2/2011

Pediatric Cardiology 2/2011 Go to the issue