Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Neuroradiology
Published in: Neuroradiology 10/2004

01-10-2004 | Diagnostic Neuroradiology

Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1

Authors: M. J. Naidich, M. T. Walker, N. R. Gottardi-Littell, G. Han, J. P. Chandler

Published in: Neuroradiology | Issue 10/2004

Login to get access

Abstract

We describe a case of cerebellar pleomorphic xanthoastrocytoma (PXA) occurring in a patient with neurofibromatosis type 1 (NF1). The histomorphology of this uncommon glial (astrocytic) neoplasm is discussed. The occurrence of this tumor within the posterior fossa is extremely rare. To our knowledge, this is the first reported case of a cerebellar PXA in a patient with NF1.
Literature
1.
Evan AJ, Fayaz I, Cusimano MD, et al. Combined pleomorphic xanthoastrocytoma-ganglioglioma of the cerebellum. Arch Pathol Lab Med 2000; 124:1707–1709.
2.
Giannini C, Scheithauer BW, Burger PC, et al. Pleomorphic xanthoastrocytoma: what do we really know about it? Cancer 1999; 85:2033–2045.
3.
Glasser RS, Rojiani AM, Mickle P, et al. Delayed occurrence of cerebellar pleomorphic xanthoastrocytoma after supratentorial pleomorphic xanthoastrocytoma removal. J Neurosurg 1995; 82:116–118.
4.
Ilgren EB, Kinnier-Wilson LM, Stiller CA. Gliomas in neurofibromatosis: a series of 89 cases. Pathol Annu 1985; 20:331–358.
5.
Kepes JJ, Rubinstein LJ, Eng LF. Pleomorphic xanthoastrocytoma: a distinctive meningocerebral glioma of young subjects with relatively favorable prognosis. A study of 12 cases. Cancer 1979; 44:1839–1852.
6.
Koeller KK, Henry JM. From the archives of the AFIP: superficial gliomas: radiologic-pathologic correlation. Radiographics 2001; 21:1533–1556.
7.
Korf BR. Malignancy in neurofibromatosis type 1. Oncologist 2000; 5:477-485.
8.
Kubo O, Sasahara A, Tajika Y, et al. Pleomorphic xanthoastrocytoma with neurofibromatosis type 1: case report. Brain Tumor Pathol 1996; 13: 79–83.
9.
Lim SC, Jang SJ, Kim YS. Cerebellar pleomorphic xanthoastrocytoma in an infant. Pathology Int 1999; 49:811–815.
10.
Lindboe CF, Cappelen J, Kepes JJ. Pleomorphic xanthoastrocytoma as a component of a cerebellar ganglioma: case report. Neurosurgery 1992; 31:353–355.
11.
Listernick R, Charrow J, Gutmann DH. Intracranial gliomas in neurofibromatosis type 1. Am J Med Genet 1999; 89: 38–44.
12.
Ohta S, Ryu H, Miura K. Eighteen-year survival of a patient with malignant pleomorphic xanthoastrocytoma associated with von Recklinghausen neurofibromatosis. Br J Neurosurg 1999; 13:420–422.
13.
Ozek MM, Sab A, Pamir MN, et al. Pleomorphic xanthoastrocytoma associated with von Recklinghausen nerurofibromatosis. Childs Nerv Syst 1993; 9:39–42.
14.
Perry A, Giannini C, Scheithauer BW, et al. Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature. Am J Surg Pathol 1997; 21:763–771.
15.
Rosemberg S, Rotta JM, Yassuda A, et al. Pleomorphic xanthoastrocytoma of the cerebellum. Clin Neuropathol 2000; 19:238–242.
16.
Tien RD, Cardenas CA, Rajagopalan S. Pleomorphic xanthoastrocytoma of the brain: MR findings in six patients. AJR Am J Roentgenol 1992; 159:1287–1290.
17.
Washdahl DA, Scheithauer BW, Andrews BT, et al. Cerebellar pleomorphic xanthoastrocytoma: case report. Neurosurgery 1994; 35:947–951.
Metadata
Title
Cerebellar pleomorphic xanthoastrocytoma in a patient with neurofibromatosis type 1
Authors
M. J. Naidich
M. T. Walker
N. R. Gottardi-Littell
G. Han
J. P. Chandler
Publication date
01-10-2004
Publisher
Springer-Verlag
Published in
Neuroradiology / Issue 10/2004
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI
https://doi.org/10.1007/s00234-004-1216-0

Other articles of this Issue 10/2004

Neuroradiology 10/2004 Go to the issue

Announcements

Announcements - October 2004

Diagnostic Neuroradiology

Reversible encephalopathy syndrome: report of 12 cases with follow-up

Diagnostic Neuroradiology

Bilateral hypoplasia of the internal carotid arteries with basilar aneurysm

Diagnostic Neuroradiology

Diffusion MR findings in cyclosporin-A induced encephalopathy

Head and Neck Radiology

Magnetic resonance imaging findings in Kimura’s disease

Diagnostic Neuroradiology

Traumatic lesions of corpus callosum: early multidetector CT findings