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01-11-2019 | Sheehan Syndrome | Original Article

Evaluation of bone texture imaging parameters on panoramic radiographs of patients with Sheehan’s syndrome: a STROBE-compliant case-control study

Authors: D. de Sá Cavalcante, M.G. da Silva Castro, A.R.P. Quidute, M.R.A. Martins, A.M.P.L. Cid, P.G. de Barros Silva, J. Cadwell Williams Jr, F.S. Neves, T.R. Ribeiro, F.W.G. Costa

Published in: Osteoporosis International | Issue 11/2019

Abstract

Summary

Sheehan’s syndrome (SHS) is a rare condition related to the risk of osteoporosis and evaluation of bone texture imaging features on panoramic radiographs would be suitable for this condition, which was the aim of the present study. Fractal dimension, lacunarity, and trabecular morphologic aspects were significantly altered in these patients.

Introduction

SHS is an important public health problem particularly in developing countries. It is characterized as postpartum hypopituitarism secondary to obstetric complications-related ischemic pituitary necrosis that shows significant systemic metabolic repercussions. Thus, this study aimed to evaluate bone texture parameters in digital panoramic radiographs of patients with SHS.

Methods

A case-control study was conducted with 30 SHS patients from an Endocrinology and Diabetology Service of reference in Brazil, and 30 age- and sex-matched healthy controls. A custom computer program measured fractal dimension, lacunarity, and some morphologic features in the following mandibular regions of interest (50 × 50 pixels): below the mental foramen (F1), between the first and second molars (M1), and at the center of the mandibular ramus (R1).

Results

The fractal analysis showed a statistically significant difference between the studied groups in all regions of interest. The fractal dimension in F1 (p = 0.016), M1 (p = 0.043), and R1 (p = 0.028) was significantly lower in SHS group, as well as lacunarity in R1 (p = 0.008). Additionally, several morphologic features were statistically significant in the SHS group (p < 0.05).

Conclusion

Therefore, individuals with SHS showed altered imaging texture parameters on panoramic radiographs, which reflect a smaller spatial organization of the bone trabeculae and, possibly, a state of reduced mineral bone density.

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Title: Evaluation of bone texture imaging parameters on panoramic radiographs of patients with Sheehan’s syndrome: a STROBE-compliant case-control study
Authors: D. de Sá Cavalcante
M.G. da Silva Castro
A.R.P. Quidute
M.R.A. Martins
A.M.P.L. Cid
P.G. de Barros Silva
J. Cadwell Williams Jr
F.S. Neves
T.R. Ribeiro
F.W.G. Costa
Publication date: 01-11-2019
Publisher: Springer London
Keyword: Sheehan Syndrome
Published in: Osteoporosis International / Issue 11/2019
Print ISSN: 0937-941X
Electronic ISSN: 1433-2965
DOI: https://doi.org/10.1007/s00198-019-05086-4

Keynote webinar | Spotlight on medication adherence

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Evaluation of bone texture imaging parameters on panoramic radiographs of patients with Sheehan’s syndrome: a STROBE-compliant case-control study

Abstract

Summary

Introduction

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Summary

Introduction

Methods

Results

Conclusion

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