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Knee Surgery, Sports Traumatology, Arthroscopy
Published in: Knee Surgery, Sports Traumatology, Arthroscopy 4/2019

01-04-2019 | KNEE

Promising early outcomes of a novel anatomic knee system

Authors: Vincent P. Galea, Mina A. Botros, Rami Madanat, Christian S. Nielsen, Charles Bragdon

Published in: Knee Surgery, Sports Traumatology, Arthroscopy | Issue 4/2019

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Abstract

Purpose

The primary aim of this study was to report the early clinical and radiographic outcomes of patients who have been treated with total knee arthroplasty (TKA) using the Persona knee system. The secondary aim was to compare patient-reported outcomes (PROs) of the Persona knee system to those of the NexGen implant.

Methods

A registry-based study of a consecutive series of 112 patients (129 knees) treated with the Persona knee system from a single center was conducted. Preoperative, 1-year, and 2-year radiographs and PROs were analyzed. Postoperative radiographs were assessed for radiolucency and component positioning. Patients were monitored for postoperative complications and revision. Two-year PROs were compared to a 1:1 propensity score-matched cohort of patients treated with the NexGen knee system.

Results

Ninety-five percent of knees were within literature-defined safe ranges of the anatomical tibiofemoral axis, tibial varus/valgus angle, femoral flexion/extension angle, and tibial slope. Radiolucency was observed in 0.9% and 1.3% of knees at one and 2 years, respectively. Two-year PRO values demonstrated clinically meaningful improvements from the preoperative values. The cumulative 2-year percent revision was 3.0% (95% confidence interval 1.9–3.8%); there were no revisions due to implant mechanical failure. Patients treated with the Persona knee system had higher KOOS symptom (p = 0.037) and KOOS QOL (p < 0.001) scores compared to patients with the NexGen knee system.

Conclusions

This knee design demonstrates excellent clinical outcomes, similar or better than the NexGen knee system, at early follow-up.

Level of evidence

III.
Literature
1.
Akagi M, Mori S, Nishimura S, Nishimura A, Asano T, Hamanishi C (2005) Variability of extraarticular tibial rotation references for total knee arthroplasty. Clin Orthop Relat Res 463:172–176CrossRef
2.
Anakwe RE, Jenkins PJ, Moran M (2011) Predicting dissatisfaction after total hip arthroplasty: a study of 850 patients. J Arthroplast 26:209–213CrossRef
3.
4.
Barr CJ, Barbalace RJ, Wessinger SJ, Bragdon CR, Kwon YM, Malchau H (2012) Validation of a hospital-based joint registry. Quantification of errors and maximizing utility. J Arthroplast 27:1766–1771CrossRef
5.
Bonnin MP, Saffarini M, Mercier P-E, Laurent J-R, Carrillon Y (2011) Is the anterior tibial tuberosity a reliable rotational landmark for the tibial component in total knee arthroplasty? J Arthroplast 26:260–267.e1-e2CrossRef
6.
Breeman S, Campbell MK, Dakin H, Fiddian N, Fitzpatrick R, Grant A, Gray A, Johnston L, MacLennan GS, Morris RW, Murray DW (2013) Five-year results of a randomised controlled trial comparing mobile and fixed bearings in total knee replacement. Bone Jt J 95–B:486–492CrossRef
7.
Collins NJ, Misra D, Felson DT, Crossley KM, Roos EM (2011) Measures of knee function. Arthritis Care Res (Hoboken) 63(Suppl 11):S208–S228CrossRef
8.
Dai Y, Scuderi GR, Penninger C, Bischoff JE, Rosenberg A (2014) Increased shape and size offerings of femoral components improve fit during total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 22:2931–2940CrossRefPubMedPubMedCentral
9.
Daigle ME, Weinstein AM, Katz JN, Losina E (2012) The cost-effectiveness of total joint arthroplasty: a systematic review of published literature. Best Pract Res Clin Rheumatol 26(5):649–658CrossRefPubMed
10.
Ewald F, C (1989) Roentgenographic evaluation and scoring system. Clin Orthop Relat Res 248:2–5
11.
Fang DM, Ritter MA, Davis KE (2009) Coronal alignment in total knee arthroplasty. Just how important is it? J Arthroplast 24:39–43CrossRef
12.
Gøthesen Espehaug B, Havelin LI, Petursson G, Hallan G, Strøm E, Dyrhovden G, Furnes O (2014) Functional outcome and alignment in computer-assisted and conventionally operated total knee replacements: a multicentre parallel-group randomised controlled trial. Bone Jt J 96B:609–618CrossRef
13.
Graceffa A, Indelli PF, Basnett K, Marcucci M (2014) Analysis of differences in bone removal during femoral box osteotomy for primary total knee arthroplasty. Joints 2:76–80CrossRefPubMedPubMedCentral
14.
Gromov K, Korchi M, Thomsen MG, Husted H, Troelsen A (2014) What is the optimal alignment of the tibial and femoral components in knee arthroplasty? An overview of the literature. Acta Orthop 85:480–487CrossRefPubMedPubMedCentral
15.
Gunaratne R, Pratt DN, Banda J, Fick DP, Khan RJK, Robertson BW (2017) Patient dissatisfaction following total knee arthroplasty: a systematic review of the literature. J Arthroplast 32(12):3854–3860CrossRef
16.
Hansen VJ, Greene ME, Bragdon MA, Nebergall AK, Barr CJ, Huddleston JI, Bragdon CR, Malchau H (2014) Registries collecting level-I through IV data: institutional and multicenter use: AAOS exhibit selection. J Bone Jt Surg 96:e160CrossRef
17.
Jenkins PJ, Clement ND, Hamilton DF, Gaston P, Patton JT, Howie CR (2013) Predicting the cost-effectiveness of total hip and knee replacement: a health economic analysis. Bone Jt J 95-B:115–121CrossRef
18.
Jeon YS, Shin JS, Jung JH, Kim MK (2016) Total knee arthroplasty using NexGen LPS-flex® improves clinical outcomes without early loosening: minimum 6-year follow-up results. J Orthop Surg Res 11(1):83CrossRefPubMedPubMedCentral
19.
Jin C, Song EK, Prakash J, Kim SK, Chan CK, Seon JK (2017) How much does the anatomical tibial component improve the bony coverage in total knee. Arthroplasty? J Arthroplast 32:1829–1833CrossRef
20.
Lachiewicz PF, Soileau ES (2014) Fixation, survival and osteolysis with a modern posterior-stabilized total knee arthroplasty. J Arthroplast 29:66–70CrossRef
21.
Mahoney OM, Kinsey T (2010) Overhang of the femoral component in total knee arthroplasty: risk factors and clinical consequences. J Bone Jt Surg 92:1115–1121CrossRef
22.
Malchau H (1995) On the importance of stepwise introduction of new hip implant technology: assessment of total hip replacement using clinical evaluation, radiostereometry, digitized radiography and a national hip registry. Thesis, Goteborg University (ISBN 91-628-1658-6)
23.
Malik A, Salas A, Ben Ari J, Ma Y, González Della Valle A (2010) Range of motion and function are similar in patients undergoing TKA with posterior stabilised and high-flexion inserts. Int Orthop 34:965–972CrossRefPubMed
24.
Morris WZ, Gebhart JJ, Goldberg VM, Wera GD (2016) Implant size availability affects reproduction of distal femoral anatomy. J Knee Surg 29:409–413PubMed
25.
Palazzo C, Jourdan C, Descamps S, Nizard R, Hamadouche M, Anract P, Boisgard S, Galvin M, Ravaud P, Poiraudeau S (2014) Determinants of satisfaction 1 year after total hip arthroplasty: the role of expectations fulfilment. BMC Musculoskelet Disord 15:1–9CrossRef
26.
Paulsen A, Roos EM, Pedersen AB, Overgaard S (2014) Minimal clinically important improvement (MCII) and patient-acceptable symptom state (PASS) in total hip arthroplasty (THA) patients 1 year postoperatively. Acta Orthop 85:39–48CrossRefPubMedPubMedCentral
27.
Ren AN, Neher RE, Bell T, Grimm J (2018) Using patient demographics and statistical modeling to predict knee tibia component sizing in total knee arthroplasty. J Arthroplast 33(6):1732–1736CrossRef
28.
Ritter M, Gioe TJ, Stringer E (1981) Radiolucency surrounding the posterior cruciate condylar total knee prosthetic components. Clin Orthop Relat Res 160:149–152
29.
Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD (1998) Knee injury and osteoarthritis outcome score (KOOS)—development of a self-administered outcome measure. J Orthop Sport Phys Ther 28:88–96CrossRef
30.
31.
Schroer WC, Stormont DM, Pietrzak WS (2014) Seven-year survivorship and functional outcomes of the high-flexion vanguard complete knee system. J Arthroplast 29:61–65CrossRef
32.
33.
Thienpont E, Vanden Berghe A, Schwab PE, Forthomme JP, Cornu O (2016) Joint awareness in osteoarthritis of the hip and knee evaluated with the ‘forgotten joint’ score before and after joint replacement. Knee Surg Sports Traumatol Arthrosc 24:3346–3351CrossRefPubMed
34.
Tomek IM, Kantor SR, Cori LAA, Scoville JM, Grove MR, Morgan TS, Swarup I, Moschetti WE, Spratt KF (2014) Early patient outcomes after primary total knee arthroplasty with quadriceps-sparing subvastus and medial parapatellar techniques: a randomized, double-blind clinical trial. J Bone Jt Surg 96:907–915CrossRef
35.
36.
37.
Zahiri CA, Schmalzried TP, Szuszczewicz ES, Amstutz HC (1998) Assessing activity in joint replacement patients. J Arthroplast 13:890–895CrossRef
Metadata
Title
Promising early outcomes of a novel anatomic knee system
Authors
Vincent P. Galea
Mina A. Botros
Rami Madanat
Christian S. Nielsen
Charles Bragdon
Publication date
01-04-2019
Publisher
Springer Berlin Heidelberg
Published in
Knee Surgery, Sports Traumatology, Arthroscopy / Issue 4/2019
Print ISSN: 0942-2056
Electronic ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-018-5248-0

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