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Intensive Care Medicine
Published in: Intensive Care Medicine 6/2021

Open Access 01-06-2021 | COVID-19 | Letter

Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients

Authors: Rutger Koning, Paul Bastard, Jean-Laurent Casanova, Matthijs C. Brouwer, Diederik van de Beek, with the Amsterdam U.M.C. COVID-19 Biobank Investigators

Published in: Intensive Care Medicine | Issue 6/2021

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Excerpt

Dear Editor, …
Appendix
Available only for authorised users
Literature
1.
Bastard P, Rosen LB, Zhang Q et al (2020) Autoantibodies against type I IFNs in patients with life-threatening COVID-19. Science 370:eabd4585CrossRef
2.
Ku CL, Chi CY, von Bernuth H, Doffinger R (2020) Autoantibodies against cytokines: phenocopies of primary immunodeficiencies? Hum Genet 139:783–794CrossRef
3.
Zhang Q, Bastard P, Bolze A, Jouanguy E, Zhang SY, Effort CHG, Cobat A, Notarangelo LD, Su HC, Abel L, Casanova JL (2020) Life-threatening COVID-19: defective interferons unleash excessive inflammation. Med (N Y) 1:14–20
Metadata
Title
Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients
Authors
Rutger Koning
Paul Bastard
Jean-Laurent Casanova
Matthijs C. Brouwer
Diederik van de Beek
with the Amsterdam U.M.C. COVID-19 Biobank Investigators
Publication date
01-06-2021
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 6/2021
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-021-06392-4

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