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01-09-2009 | Correspondence

Soluble triggering receptor expressed on myeloid cells-1 and diagnosis of ventilator-associated pneumonia

Author: Sébastien Gibot

Published in: Intensive Care Medicine | Issue 9/2009

Excerpt

Dear Sir: The quest for a reliable diagnostic marker of ventilator-associated pneumonia (VAP) is still ongoing and whether determination of the alveolar concentration of the soluble form of the triggering receptor expressed on myeloid cells (TREM)-1 could be a valuable candidate is debated. Unfortunately, the study reported in this issue of Intensive Care Medicine will just generate further perplexity [1]. …

Oudhuis GF, Beuving J, Bergmans D, Stobberingh EE, ten Velde G, Linssen CF, Verbon A (2009) Soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid is not predictive for ventilator-associated pneumonia. Intensive Care Med. doi: 10.1007/s00134-009-1463-y

Linssen CF, Jacobs JA, Schouten JS, van Mook WN, Ramsay G, Drent M (2008) Influence of antibiotic therapy on the cytological diagnosis of ventilator-associated pneumonia. Intensive Care Med 34:865–872PubMedCrossRef

Determann RM, Millo JL, Gibot S, Korevaar JC, Vroom MB, van der Poll T, Garrard CS, Schultz MJ (2005) Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia. Intensive Care Med 31:1495–1500PubMedCrossRef

Huh JW, Lim CM, Koh Y, Oh YM, Shim TS, Lee SD, Kim WS, Kim DS, Kim WD, Hong SB (2008) Diagnostic utility of the soluble triggering receptor expressed on myeloid cells-1 in bronchoalveolar lavage fluid from patients with bilateral lung infiltrates. Crit Care 12:R6PubMedCrossRef

El-Sohl A, Akinnussi ME, Peter M, Berim I, Schultz MJ, Pineda L (2008) Triggering receptors expressed on myeloid cells in pulmonary aspiration syndromes. Intensive Care Med 34:1012–1019CrossRef

Anand NJ, Zuick S, Klesney-Tait J, Kollef MH (2009) Diagnostic implications of soluble triggering receptor expressed on myeloid cells-1 in BAL fluid of patients with pulmonary infiltrates in the ICU. Chest 135:641–647PubMedCrossRef

Title: Soluble triggering receptor expressed on myeloid cells-1 and diagnosis of ventilator-associated pneumonia
Author: Sébastien Gibot
Publication date: 01-09-2009
Publisher: Springer-Verlag
Published in: Intensive Care Medicine / Issue 9/2009
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1547-8

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Soluble triggering receptor expressed on myeloid cells-1 and diagnosis of ventilator-associated pneumonia

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