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Published in: Intensive Care Medicine 7/2007

01-07-2007 | Original

Assist-control ventilation vs. low levels of pressure support ventilation on sleep quality in intubated ICU patients

Authors: Bénédicte Toublanc, Dominique Rose, Jean-Charles Glérant, Géraldine Francois, Isabelle Mayeux, Daniel Rodenstein, Vincent Jounieaux

Published in: Intensive Care Medicine | Issue 7/2007

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Abstract

Objective

To compare the impact of assist-control ventilation (ACV) and pressure support ventilation with 6 cmH2O inspiratory pressure (low PSV) on sleep quality.

Design

Prospective randomized cross-over study.

Patients

Twenty intubated and mechanically ventilated patients for acute on chronic respiratory failure.

Measurements

Patients were monitored by standard polysomnography at the end of their weaning period. Patients were assigned to receive either ACV from 10 p.m. to 2 a.m. and low PSV from 2 a.m. to 6 a.m. (ACV/low PSV group) or low PSV from 10 p.m. to 2 a.m. and ACV from 2 a.m. to 6 a.m. (low PSV/ACV group).

Results

There were significant increases in stages 1 and 2 non-rapid eye movement (NREM) sleep and reduction in wakefulness during the first part of the night and significant increases in stages 3 and 4 NREM sleep during the second part of the night were observed with ACV compared to low PSV. A significant negative correlation was observed between the perceived sleep quality and the amount of wakefulness while the amount of stage 2 NREM sleep was positively correlated with perceived sleep quality.

Conclusions

ACV was significantly associated with a better sleep quality than those recorded during pressure support. The perception of sleep quality appeared to be better with ACV than with low PSV. On the basis of these results we recommend that intubated and mechanically ventilated patients for acute on chronic respiratory failure should be reventilated at night during their weaning period.
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Metadata
Title
Assist-control ventilation vs. low levels of pressure support ventilation on sleep quality in intubated ICU patients
Authors
Bénédicte Toublanc
Dominique Rose
Jean-Charles Glérant
Géraldine Francois
Isabelle Mayeux
Daniel Rodenstein
Vincent Jounieaux
Publication date
01-07-2007
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 7/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-007-0659-2

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