Published in:
01-07-2007 | Original
Assist-control ventilation vs. low levels of pressure support ventilation on sleep quality in intubated ICU patients
Authors:
Bénédicte Toublanc, Dominique Rose, Jean-Charles Glérant, Géraldine Francois, Isabelle Mayeux, Daniel Rodenstein, Vincent Jounieaux
Published in:
Intensive Care Medicine
|
Issue 7/2007
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Abstract
Objective
To compare the impact of assist-control ventilation (ACV) and pressure support ventilation with 6 cmH2O inspiratory pressure (low PSV) on sleep quality.
Design
Prospective randomized cross-over study.
Patients
Twenty intubated and mechanically ventilated patients for acute on chronic respiratory failure.
Measurements
Patients were monitored by standard polysomnography at the end of their weaning period. Patients were assigned to receive either ACV from 10 p.m. to 2 a.m. and low PSV from 2 a.m. to 6 a.m. (ACV/low PSV group) or low PSV from 10 p.m. to 2 a.m. and ACV from 2 a.m. to 6 a.m. (low PSV/ACV group).
Results
There were significant increases in stages 1 and 2 non-rapid eye movement (NREM) sleep and reduction in wakefulness during the first part of the night and significant increases in stages 3 and 4 NREM sleep during the second part of the night were observed with ACV compared to low PSV. A significant negative correlation was observed between the perceived sleep quality and the amount of wakefulness while the amount of stage 2 NREM sleep was positively correlated with perceived sleep quality.
Conclusions
ACV was significantly associated with a better sleep quality than those recorded during pressure support. The perception of sleep quality appeared to be better with ACV than with low PSV. On the basis of these results we recommend that intubated and mechanically ventilated patients for acute on chronic respiratory failure should be reventilated at night during their weaning period.