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01-01-2015 | Review article

DEGRO guidelines for the radiotherapy of non-malignant disorders

Part II: Painful degenerative skeletal disorders

Authors: PD Dr. med. Oliver J. Ott, Marcus Niewald, Hajo-Dirk Weitmann, Ingrid Jacob, Irenaeus A. Adamietz, Ulrich Schaefer, Ludwig Keilholz, Reinhard Heyd, Ralph Muecke, German Cooperative Group on Radiotherapy for Benign Diseases (GCG-BD)

Published in: Strahlentherapie und Onkologie | Issue 1/2015

Abstract

Background and purpose

The purpose of this article is to summarize the updated DEGRO consensus S2e guideline recommendations for the treatment of benign painful degenerative skeletal disorders with low-dose radiotherapy.

Materials and methods

This overview reports on the role of low-dose radiotherapy in the treatment of enthesiopathies (shoulder syndrome, trochanteric bursitis, plantar fasciitis, and elbow syndrome) and painful arthrosis (knee, hip, hand, and finger joints). The most relevant aspects of the DEGRO S2e Consensus Guideline Radiation Therapy of Benign Diseases 2014 regarding diagnostics, treatment decision, dose prescription as well as performance of radiotherapy and results are summarized.

Results

For all indications mentioned above, retrospective and some prospective analyses have shown remarkable effects in terms of pain relief. Nevertheless, the Level of Evidence (LoE) and the Grade of Recommendation (GR) vary: LoE 1b–4 and GR A–C.

Conclusion

Low-dose radiotherapy for painful degenerative skeletal disorders is effective in the majority of the patients and therefore it may be a reasonable therapeutic alternative when simple and non-invasive methods have been used without persistent success. For all discussed entities, single fraction doses of 0.5–1.0 Gy and total doses of 3.0–6.0 Gy/series applied with 2–3 fractions per week are recommended.

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Title: DEGRO guidelines for the radiotherapy of non-malignant disorders
Part II: Painful degenerative skeletal disorders
Authors: PD Dr. med. Oliver J. Ott
Marcus Niewald
Hajo-Dirk Weitmann
Ingrid Jacob
Irenaeus A. Adamietz
Ulrich Schaefer
Ludwig Keilholz
Reinhard Heyd
Ralph Muecke
German Cooperative Group on Radiotherapy for Benign Diseases (GCG-BD)
Publication date: 01-01-2015
Publisher: Springer Berlin Heidelberg
Published in: Strahlentherapie und Onkologie / Issue 1/2015
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-014-0757-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

DEGRO guidelines for the radiotherapy of non-malignant disorders

Part II: Painful degenerative skeletal disorders

Abstract

Background and purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background and purpose

Materials and methods

Results

Conclusion

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