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Netherlands Heart Journal

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01-11-2009 | Interuniversity Cardiology Institute of the Netherlands

Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography

Authors: G. van Soest, T. P. M. Goderie, N. Gonzalo, S. Koljenović, G. L. J. H. van Leenders, E. Regar, P. W. Serruys, A. F. W. van der Steen

Published in: Netherlands Heart Journal | Issue 11/2009

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Abstract

Optical coherence tomography (OCT) allows highly accurate diagnosis of atherosclerotic plaques, including measurement of the thickness of fibrous caps, permitting an assessment of the risk of rupture. While the OCT image presents morphological information in highly resolved detail, it relies on interpretation by trained readers for the identification of tissue type. We developed a method for quantitative classification of atherosclerotic plaque constituents. The optical attenuation coefficient μ _t distinguishes different tissue types: necrotic core and macrophage infiltration exhibit strong attenuation, μ _t≥10 mm⁻¹, while calcific and fibrous tissue have a lower μ _t≈2–5 mm⁻¹. (Neth Heart J 2009;17:448–50.)

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Title: Imaging atherosclerotic plaque composition with intracoronary optical coherence tomography
Authors: G. van Soest
T. P. M. Goderie
N. Gonzalo
S. Koljenović
G. L. J. H. van Leenders
E. Regar
P. W. Serruys
A. F. W. van der Steen
Publication date: 01-11-2009
Publisher: Bohn Stafleu van Loghum
Published in: Netherlands Heart Journal / Issue 11/2009
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI: https://doi.org/10.1007/BF03086301

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