Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Netherlands Heart Journal
Published in: Netherlands Heart Journal 1/2008

01-01-2008 | editorial

Imaging in cardiac resynchronisation therapy

Authors: C. Ypenburg, E. E. van der Wall, M. J. Schalij, J. J. Bax

Published in: Netherlands Heart Journal | Issue 1/2008

Login to get access

Extract

Cardiac resynchronisation therapy (CRT) is an effective treatment for patients with advanced heart failure (HF) (New York Heart Association class (NYHA) III or IV), depressed left ventricular ejection fraction (LVEF, <35%) and wide QRS complexes (>120 ms) as demonstrated in various large multicentre trials. The beneficial effects include improvement in HF symptoms, exercise capacity, and LV function, as well as less HF hospitalisations and lower mortality rates.1 Despite these impressive results, a consistent percentage of patients show no benefit after CRT, the so-called ‘non-responders’. The prevalence of non-responders is around 30% when clinical endpoints are used (e.g. improvement in NYHA class or exercise capacity), but can be much higher, up to 50%, when echocardiographic endpoints, such as improvement in LV function or reduction in LV end-systolic volume (LVESV), are used.1 …
Literature
1.
McAlister FA, Ezekowitz J, Hooton N, Vandermeer B, Spooner C, Dryden DM, et al. Cardiac resynchronization therapy for patients with left ventricular systolic dysfunction: a systematic review. JAMA 2007;297:2502-14.
2.
Bax JJ, Abraham T, Barold SS, Breithardt OA, Fung JW, Garrigue S, et al. Cardiac resynchronization therapy part 1-issues before device implantation. J Am Coll Cardiol 2005;46:2153-67.
3.
Ghio S, Constantin C, Klersy C, Serio A, Fontana A, Campana C, et al. Interventricular and intraventricular dyssynchrony are common in heart failure patients, regardless of QRS duration. Eur Heart J 2004;25:571-8.
4.
Pitzalis MV, Iacoviello M, Romito R, Massari F, Rizzon B, Luzzi G, et al. Cardiac resynchronization therapy tailored by echocardiographic evaluation of ventricular asynchrony. J Am Coll Cardiol 2002;40:1615-22.
5.
Bleeker GB, Schalij MJ, Boersma E, Holman ER, Steendijk P, van der Wall EE, et al. Relative merits of M-mode echocardiography and tissue Doppler imaging for prediction of response to cardiac resynchronization therapy in patients with heart failure secondary to ischemic or idiopathic dilated cardiomyopathy. Am J Cardiol 2007;99:68-74.
6.
Penicka M, Bartunek J, De Bruyne B, Vanderheyden M, Goethals M, De Zutter M, et al. Improvement of left ventricular function after cardiac resynchronization therapy is predicted by tissue Doppler imaging echocardiography. Circulation 2004;109:978-83.
7.
Bax JJ, Bleeker GB, Marwick TH, Molhoek SG, Boersma E, Steendijk P, et al. Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy. J Am Coll Cardiol 2004;44:1834-40.
8.
Yu CM, Gorcsan J III, Bleeker GB, Zhang Q, Schalij MJ, Suffoletto MS, et al. Usefulness of tissue Doppler velocity and strain dyssynchrony for predicting left ventricular reverse remodeling response after cardiac resynchronization therapy. Am J Cardiol 2007;100:1263-70.
9.
Van de Veire NR, Bleeker GB, De Sutter J, Ypenburg C, Holman ER, van der Wall EE, et al. Tissue synchronisation imaging accurately measures left ventricular dyssynchrony and predicts response to cardiac resynchronisation therapy. Heart 2007;93:1034-9.
10.
Yu CM, Zhang Q, Chan YS, Chan CK, Yip GW, Kum LC, et al. Tissue Doppler velocity is superior to displacement and strain mapping in predicting left ventricular reverse remodelling response after cardiac resynchronisation therapy. Heart 2006;92:1452-6.
11.
Suffoletto MS, Dohi K, Cannesson M, Saba S, Gorcsan J III. Novel speckle-tracking radial strain from routine black-and-white echocardiographic images to quantify dyssynchrony and predict response to cardiac resynchronization therapy. Circulation 2006;113:960-8.
12.
Ajmone Marsan N, Bleeker GB, Ypenburg C, Ghio S, Van de Veire NR, Holman ER, et al. Real-Time Three-Dimensional Echocardiography Permits Quantification of Left Ventricular Mechanical Dyssynchrony and Predicts Acute Response to Cardiac Resynchronization Therapy. J Cardiovasc Electrophysiol 2008;19:392-9.
13.
Westenberg JJ, Lamb HJ, van der Geest RJ, Bleeker GB, Holman ER, Schalij MJ, et al. Assessment of left ventricular dyssynchrony in patients with conduction delay and idiopathic dilated cardiomyopathy: head-to-head comparison between tissue doppler imaging and velocity-encoded magnetic resonance imaging. J Am Coll Cardiol 2006;47:2042-8.
14.
Bleeker GB, Kaandorp TA, Lamb HJ, Boersma E, Steendijk P, de Roos A, et al. Effect of posterolateral scar tissue on clinical and echocardiographic improvement after cardiac resynchronization therapy. Circulation 2006;113:969-76.
15.
Henneman MM, Chen J, Dibbets-Schneider P, Stokkel MP, Bleeker GB, Ypenburg C, et al. Dyssynchrony as Assessed with Phase Analysis on Gated Myocardial Perfusion SPECT Predict Response to CRT? J Nucl Med 2007;48:1104-11.
16.
Sciagra R, Giaccardi M, Porciani MC, Colella A, Michelucci A, Pieragnoli P, et al. Myocardial perfusion imaging using gated SPECT in heart failure patients undergoing cardiac resynchronization therapy. J Nucl Med 2004;45:164-8.
17.
Van de Veire NR, Schuijf JD, De Sutter J, Devos D, Bleeker GB, de Roos A, et al. Non-invasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography. J Am Coll Cardiol 2006;48:1832-8.
Metadata
Title
Imaging in cardiac resynchronisation therapy
Authors
C. Ypenburg
E. E. van der Wall
M. J. Schalij
J. J. Bax
Publication date
01-01-2008
Publisher
Bohn Stafleu van Loghum
Published in
Netherlands Heart Journal / Issue 1/2008
Print ISSN: 1568-5888
Electronic ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03086204

Other articles of this Issue 1/2008

Netherlands Heart Journal 1/2008 Go to the issue

Special article

History of echocardiography in the Netherlands: 30 years of education and clinical applications

article

The first 20 years of bradypacing in the Netherlands - with special reference to organisational structures

article

Permanent cardiac pacing for neurocardiogenic syncope

Interuniversity Cardiology Institute of the Netherlands

Epigenetic histone acetylation modifiers in vascular remodelling – new targets for therapy in cardiovascular disease

article

Complications and lead extraction in cardiac pacing and defibrillation

Imaging in cardiology

Thrombus in a normal left ventricle