Skip to main content
Top
Published in: BMC Medicine 1/2024

Open Access 01-12-2024 | Overweight | Opinion

Toward evidence-based communication on overweight body mass index and mortality

Authors: Maya B. Mathur, Vandana S. Mathur

Published in: BMC Medicine | Issue 1/2024

Login to get access

Abstract

Background

Reducing overweight and obesity has been a longstanding focus of public health messaging and physician–patient interactions. Clinical guidelines by major public health organizations describe both overweight and obesity as risk factors for mortality and other health conditions. Accordingly, a majority of primary care physicians believe that overweight BMI (even without obesity) strongly increases mortality risk.

Main points

The current evidence base suggests that although both obese BMI and underweight BMI are consistently associated with increased all-cause mortality, overweight BMI (without obesity) is not meaningfully associated with increased mortality. In fact, a number of studies suggest modest protective, rather than detrimental, associations of overweight BMI with all-cause mortality. Given this current evidence base, clinical guidelines and physician perceptions substantially overstate all-cause mortality risks associated with the range of BMIs classified as “overweight” but not “obese.” Discrepancies between evidence and communication regarding mortality raise the question of whether similar discrepancies exist for other health outcomes.

Conclusions

Health communication that inaccurately conveys current evidence may do more harm than good; this applies to communication from health authorities to health practitioners as well as to communication from health practitioners to individual patients. We give three recommendations to better align health communication with the current evidence. First, recommendations to the public and health practitioners should distinguish overweight from obese BMI and at this time should not describe overweight BMI as a risk factor for all-cause mortality. Second, primary care physicians’ widespread misconceptions about overweight BMI should be rectified. Third, the evidence basis for other potential risks or benefits of overweight BMI should be rigorously examined and incorporated appropriately into health communication.
Literature
3.
go back to reference Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, Hu FB, Hubbard VS, Jakicic JM, Kushner RF, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63:2985–3023.CrossRefPubMed Jensen MD, Ryan DH, Apovian CM, Ard JD, Comuzzie AG, Donato KA, Hu FB, Hubbard VS, Jakicic JM, Kushner RF, et al. 2013 AHA/ACC/TOS guideline for the management of overweight and obesity in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and The Obesity Society. J Am Coll Cardiol. 2014;63:2985–3023.CrossRefPubMed
4.
go back to reference Mathur MB, Mathur VS. Primary care physicians’ perceptions of the effects of being overweight on all-cause mortality. Epidemiology. 2023;34:e19–20.CrossRefPubMedPubMedCentral Mathur MB, Mathur VS. Primary care physicians’ perceptions of the effects of being overweight on all-cause mortality. Epidemiology. 2023;34:e19–20.CrossRefPubMedPubMedCentral
5.
go back to reference McHale CT, Laidlaw AH, Cecil JE. Primary care patient and practitioner views of weight and weight-related discussion: a mixed-methods study. BMJ Open. 2020;10:e034023.CrossRefPubMedPubMedCentral McHale CT, Laidlaw AH, Cecil JE. Primary care patient and practitioner views of weight and weight-related discussion: a mixed-methods study. BMJ Open. 2020;10:e034023.CrossRefPubMedPubMedCentral
6.
go back to reference Lindberg CS, Sandbaek A, Jensen SD, Meldgaard Bruun J, Andreassen P. Communication about weight-related issues with adult patients with obesity in general practice: a scoping review. Obes Sci Pract. 2023;9:548–70.CrossRefPubMedPubMedCentral Lindberg CS, Sandbaek A, Jensen SD, Meldgaard Bruun J, Andreassen P. Communication about weight-related issues with adult patients with obesity in general practice: a scoping review. Obes Sci Pract. 2023;9:548–70.CrossRefPubMedPubMedCentral
7.
go back to reference Mathur MB, VanderWeele TJ. Assessing uncontrolled confounding in associations of being overweight with all-cause mortality. JAMA Netw Open. 2022;5:e222614–e222614.CrossRefPubMedPubMedCentral Mathur MB, VanderWeele TJ. Assessing uncontrolled confounding in associations of being overweight with all-cause mortality. JAMA Netw Open. 2022;5:e222614–e222614.CrossRefPubMedPubMedCentral
8.
go back to reference Mathur MB, VanderWeele TJ. The authors respond: Effects of being overweight on mortality are unclear given multiple methodological problems. Epidemiology. 2023;33:e22–3.CrossRef Mathur MB, VanderWeele TJ. The authors respond: Effects of being overweight on mortality are unclear given multiple methodological problems. Epidemiology. 2023;33:e22–3.CrossRef
9.
go back to reference Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013;309:71–82.CrossRefPubMedPubMedCentral Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013;309:71–82.CrossRefPubMedPubMedCentral
10.
go back to reference Di Angelantonio E, Bhupathiraju SN, Wormser D, Gao P, Kaptoge S, De Gonzalez AB, Cairns BJ, Huxley R, Jackson CL, Joshy G, et al. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. The Lancet. 2016;388:776–86.CrossRef Di Angelantonio E, Bhupathiraju SN, Wormser D, Gao P, Kaptoge S, De Gonzalez AB, Cairns BJ, Huxley R, Jackson CL, Joshy G, et al. Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents. The Lancet. 2016;388:776–86.CrossRef
11.
go back to reference Winter JE, MacInnis RJ, Wattanapenpaiboon N, Nowson CA. BMI and all-cause mortality in older adults: a meta-analysis. Am J Clin Nutr. 2014;99:875–90.CrossRefPubMed Winter JE, MacInnis RJ, Wattanapenpaiboon N, Nowson CA. BMI and all-cause mortality in older adults: a meta-analysis. Am J Clin Nutr. 2014;99:875–90.CrossRefPubMed
12.
go back to reference Mathur MB, VanderWeele TJ. Methods to address confounding and other biases in meta-analyses: review and recommendations. Annu Rev Public Health. 2022;43:19–35.CrossRefPubMed Mathur MB, VanderWeele TJ. Methods to address confounding and other biases in meta-analyses: review and recommendations. Annu Rev Public Health. 2022;43:19–35.CrossRefPubMed
13.
go back to reference Sanchez-Lastra MA, Ding D, Dalene KE, del Pozo Cruz B, Ekelund U, Tarp J. Body composition and mortality from middle to old age: a prospective cohort study from the UK Biobank. Int J Obes. 2023;47:709–16.CrossRef Sanchez-Lastra MA, Ding D, Dalene KE, del Pozo Cruz B, Ekelund U, Tarp J. Body composition and mortality from middle to old age: a prospective cohort study from the UK Biobank. Int J Obes. 2023;47:709–16.CrossRef
14.
go back to reference Banack HR, Kaufman JS. Estimating the time-varying joint effects of obesity andsmoking on all-cause mortality using marginal structural models. Am J Epidemiol. 2016;183:122–9.PubMed Banack HR, Kaufman JS. Estimating the time-varying joint effects of obesity andsmoking on all-cause mortality using marginal structural models. Am J Epidemiol. 2016;183:122–9.PubMed
15.
go back to reference Yu E, Ley SH, Manson JE, Willett W, Satija A, Hu FB, Stokes A. Weight history and all-cause and cause-specific mortality in three prospective cohort studies. Ann Intern Med. 2017;166:613–20.CrossRefPubMedPubMedCentral Yu E, Ley SH, Manson JE, Willett W, Satija A, Hu FB, Stokes A. Weight history and all-cause and cause-specific mortality in three prospective cohort studies. Ann Intern Med. 2017;166:613–20.CrossRefPubMedPubMedCentral
16.
go back to reference Flegal KM. Use and misuse of BMI categories. AMA J Ethics. 2023;25:550–8.CrossRef Flegal KM. Use and misuse of BMI categories. AMA J Ethics. 2023;25:550–8.CrossRef
17.
go back to reference Christou NV, Sampalis JS, Liberman M, Look D, Auger S, McLean AP, MacLean LD. Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg. 2004;240:416–24.CrossRefPubMedPubMedCentral Christou NV, Sampalis JS, Liberman M, Look D, Auger S, McLean AP, MacLean LD. Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients. Ann Surg. 2004;240:416–24.CrossRefPubMedPubMedCentral
18.
go back to reference Malhotra R, Østbye T, Riley CM, Finkelstein EA. Young adult weight trajectories through midlife by body mass category. Obesity. 2013;21:1923–34.CrossRefPubMed Malhotra R, Østbye T, Riley CM, Finkelstein EA. Young adult weight trajectories through midlife by body mass category. Obesity. 2013;21:1923–34.CrossRefPubMed
Metadata
Title
Toward evidence-based communication on overweight body mass index and mortality
Authors
Maya B. Mathur
Vandana S. Mathur
Publication date
01-12-2024
Publisher
BioMed Central
Published in
BMC Medicine / Issue 1/2024
Electronic ISSN: 1741-7015
DOI
https://doi.org/10.1186/s12916-024-03402-2

Other articles of this Issue 1/2024

BMC Medicine 1/2024 Go to the issue