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01-12-2024 | Ureterorenoscopy | Original Article

Risk factors of early infectious complications after ureterorenoscopy for stone disease: a prospective study

Authors: Brecht Devos, Wies Vanderbruggen, Marc Claessens, Aline Duchateau, Robert Hente, Etienne Xavier Keller, Amelia Pietropaolo, Ben Van Cleynenbreugel, Vincent De Coninck

Published in: World Journal of Urology | Issue 1/2024

Abstract

Purpose

To prospectively evaluate the rate and associated risk factors of early infectious complications after ureterorenoscopy for urolithiasis.

Methods

After ethical committee approval, 400 therapeutic retrograde ureterorenoscopy procedures between August 3, 2020 and November 24, 2021 were included for analysis in a single-center study. Postoperative infection was defined as an afebrile urinary tract infection, fever (≥ 38 °C) with pyuria (≥ 300 WBC/μL) or proven urinary pathogen, and urosepsis. The primary outcome was the rate of infectious complications after ureterorenoscopy. Secondary outcomes were the perioperative factors that increased the risk of infectious complications within 30 days of surgery using univariate and multivariate logistic regression analysis.

Results

Twenty-nine of four hundred (7.3%) patients developed an infectious complication within 30 days after ureterorenoscopy. Ten (2.5%) patients developed an afebrile urinary tract infection, eight (2.0%) developed fever with pyuria, five (1.3%) febrile urinary tract infection, and six (1.5%) urosepsis. On univariate analysis, preoperative stent-type JFil^® pigtail suture stent was significantly associated with the dependent variable (p < 0.001). On multivariate logistic regression analysis, older age (OR 1.035; 95% CI 1.006–1.070; p = 0.02) was found to be significantly associated with developing a postoperative infectious complication.

Conclusions

A 7.3% rate of postoperative infectious complications and 1.5% urosepsis rate were observed after therapeutic ureterorenoscopy, without the need of intensive care admission. The only significant risk factors were preoperative stent type (JFil^® pigtail suture stent) on univariate analysis, and older age on multivariate logistic regression analysis. Further multicentric prospective observational data are needed in this field.

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Title: Risk factors of early infectious complications after ureterorenoscopy for stone disease: a prospective study
Authors: Brecht Devos
Wies Vanderbruggen
Marc Claessens
Aline Duchateau
Robert Hente
Etienne Xavier Keller
Amelia Pietropaolo
Ben Van Cleynenbreugel
Vincent De Coninck
Publication date: 01-12-2024
Publisher: Springer Berlin Heidelberg
Keywords: Ureterorenoscopy
Urosepticemia
Urinary Tract Infection
Urolithiasis
Published in: World Journal of Urology / Issue 1/2024
Print ISSN: 0724-4983
Electronic ISSN: 1433-8726
DOI: https://doi.org/10.1007/s00345-024-04983-6

2024 ASCO Annual Meeting

Springer Medicine

Risk factors of early infectious complications after ureterorenoscopy for stone disease: a prospective study

Abstract

Purpose

Methods

Results

Conclusions

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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