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Published in: Indian Journal of Thoracic and Cardiovascular Surgery 3/2024

Open Access 20-12-2023 | Aortic Valve Replacement | Original Article

Transaortic septal myectomy at the time of aortic valve replacement for severe aortic stenosis: a case series of 55 cases

Authors: Georgios Theodoros Karapanagiotidis, Evangelos Anastasakis, Chrysoula Nana, Philemon Sylvester Gukop, Mustafa Zakkar, Paschalis Tossios, Vasilios Grosomanidis, Despoina Sarridou, Dimitrios Krimiotis, Mazin Abdulla Ibrahim Sarsam

Published in: Indian Journal of Thoracic and Cardiovascular Surgery | Issue 3/2024

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Abstract

Introduction

Symptomatic aortic valve stenosis (AS) is associated with asymmetric basal septal hypertrophy (ABSH) in 10% of cases. In this cohort, it has been suggested that rectification of the left ventricular outflow tract obstruction (LVOTO) by concomitant septal myectomy (CSM) can improve the results of aortic valve replacement (AVR).

Objective

This study aims to present the technique of AVR with CSM for severe AS with ABSH and to determine the associated early and late post-operative outcomes.

Methods

Fifty-five patients were prospectively recruited to undergo AVR with CSM between 2011 and 2021 at two centres. The primary outcomes were mortality within 30 days, incidence of post-operative ventricular septal defects (VSD) and prosthetic valve sizing. The secondary outcomes were in-hospital complications, permanent pacemaker implantation (PPI), survival at 15 months and changes on transthoracic echocardiogram.

Results

Post-operative mortality was 1.8% and this figure was unchanged at 15-month follow-up. No patients developed a post-operative VSD. Intra-operatively, it was found that in 94.6% cases the direct valve sizing increased by one, when compared to the measurement made before CSM. The indexed effective orifice area (iEOA) was > 85 cm2/m2 in 96.4% and no patients had an iEOA ≤ 0.75 cm2/m2. Four patients (7.3%) required PPI due to complete atrioventricular block.

Conclusion

AVR with CSM is a simple technique that can be utilised in severe AS with ABSH. There does not appear to be an increase in mortality or incidence of iatrogenic VSDs. Importantly, CSM allows for the implantation of a larger aortic valve compared to measurements made before CSM.
Literature
2.
go back to reference Di Tommaso L, Stassano P, Mannacio V, Russolillo V, Monaco M, Pinna G, et al. Asymmetric septal hypertrophy in patients with severe aortic stenosis: the usefulness of associated septal myectomy. J Thorac Cardiovasc Surg. 2013;145:171–5. Available from: https://pubmed.ncbi.nlm.nih.gov/22341422/. Di Tommaso L, Stassano P, Mannacio V, Russolillo V, Monaco M, Pinna G, et al. Asymmetric septal hypertrophy in patients with severe aortic stenosis: the usefulness of associated septal myectomy. J Thorac Cardiovasc Surg. 2013;145:171–5. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​22341422/​.
3.
go back to reference Fairbairn TA, Steadman CD, Mather AN, Motwani M, Blackman DJ, Plein S, et al. Assessment of valve haemodynamics, reverse ventricular remodelling and myocardial fibrosis following transcatheter aortic valve implantation compared to surgical aortic valve replacement: a cardiovascular magnetic resonance study. Heart. 2013;99:1185–91.CrossRefPubMed Fairbairn TA, Steadman CD, Mather AN, Motwani M, Blackman DJ, Plein S, et al. Assessment of valve haemodynamics, reverse ventricular remodelling and myocardial fibrosis following transcatheter aortic valve implantation compared to surgical aortic valve replacement: a cardiovascular magnetic resonance study. Heart. 2013;99:1185–91.CrossRefPubMed
4.
go back to reference Tuseth N, Cramariuc D, Rieck ÅE, Wachtell K, Gerdts E. Asymmetric septal hypertrophy – a marker of hypertension in aortic stenosis (a SEAS substudy). Blood Press. 2010;19:140–4.CrossRefPubMed Tuseth N, Cramariuc D, Rieck ÅE, Wachtell K, Gerdts E. Asymmetric septal hypertrophy – a marker of hypertension in aortic stenosis (a SEAS substudy). Blood Press. 2010;19:140–4.CrossRefPubMed
9.
go back to reference von Aspern K, Bianchi E, Haunschild J, Dahlenburg C, Misfeld M, Borger MA, et al. Propensity score matched comparison of isolated, elective aortic valve replacement with and without concomitant septal myectomy: is it worth it? J Cardiovasc Surg. 2021;62:258–67. Available from: https://pubmed.ncbi.nlm.nih.gov/32885927/. von Aspern K, Bianchi E, Haunschild J, Dahlenburg C, Misfeld M, Borger MA, et al. Propensity score matched comparison of isolated, elective aortic valve replacement with and without concomitant septal myectomy: is it worth it? J Cardiovasc Surg. 2021;62:258–67. Available from: https://​pubmed.​ncbi.​nlm.​nih.​gov/​32885927/​.
11.
Metadata
Title
Transaortic septal myectomy at the time of aortic valve replacement for severe aortic stenosis: a case series of 55 cases
Authors
Georgios Theodoros Karapanagiotidis
Evangelos Anastasakis
Chrysoula Nana
Philemon Sylvester Gukop
Mustafa Zakkar
Paschalis Tossios
Vasilios Grosomanidis
Despoina Sarridou
Dimitrios Krimiotis
Mazin Abdulla Ibrahim Sarsam
Publication date
20-12-2023
Publisher
Springer Nature Singapore
Published in
Indian Journal of Thoracic and Cardiovascular Surgery / Issue 3/2024
Print ISSN: 0970-9134
Electronic ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-023-01661-x

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