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Reproductive Biology and Endocrinology
Published in: Reproductive Biology and Endocrinology 1/2018

Open Access 01-12-2018 | Review

Lifestyle and fertility: the influence of stress and quality of life on female fertility

Authors: Stefano Palomba, Jessica Daolio, Sara Romeo, Francesco Antonino Battaglia, Roberto Marci, Giovanni Battista La Sala

Published in: Reproductive Biology and Endocrinology | Issue 1/2018

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Abstract

There is growing evidence that lifestyle choices account for the overall quality of health and life (QoL) reflecting many potential lifestyle risks widely associated with alterations of the reproductive function up to the infertility. This review aims to summarize in a critical fashion the current knowledge about the potential effects of stress and QoL on female reproductive function. A specific literature search up to August 2017 was performed in IBSS, SocINDEX, Institute for Scientific Information, PubMed, Web of Science and Google Scholar. Current review highlights a close relationship in women between stress, QoL and reproductive function, that this association is more likely reported in infertile rather than fertile women, and that a vicious circle makes them to have supported each other. However, a precise cause-effect relationship is still difficult to demonstrate due to conflicting results and the lack of objective measures/instruments of evaluation.
Literature
1.
Selye H. A syndrome produced by diverse nocuous agents. Nature. 1936;138(3479, July 4):32.CrossRef
2.
Koolhaas JM, Bartolomucci A, Buwalda B, de Boer SF, Flügge G, Korte SM, Meerlo P, Murison R, Olivier B, Palanza P, Richter-Levin G, Sgoifo A, Steimer T, Stiedl O, van Dijk G, Wöhr M, Fuchs E. Stress revisited: a critical evaluation of the stress concept. Neurosci Biobehav Rev. 2011;35:1291–301.CrossRefPubMed
3.
Elliott GR, Eisdorfer C, editors. Institute of Medicine National Academy of Sciences (U.S.). Stress and human health: analysis and implications of research: a study. New York: Springer Publishing; 1982.
4.
5.
World Health Organization. World Health Organization quality of life assessment (WHOQOL): position paper from the World Health Organization. Soc Sci Med. 1995;41:1403–9.CrossRef
6.
Sandler B. Emotional stress and infertility. Practitioner. 1960;184:355–61.PubMed
7.
8.
Aarts JW, van Empel IW, Boivin J, Nelen WL, Kremer JA, Verhaak CM. Relationship between quality of life and distress in infertility: a validation study of the Dutch FertiQoL. Hum Reprod. 2011;26:1112–8.PubMedCrossRef
9.
Williams NI, Berga SL, Cameron JL. Synergism between psychosocial and metabolic stressors: impact on reproductive function in cynomolgus monkeys. Am J Physiol Endocrinol Metab. 2007;293:E270–6.PubMedCrossRef
10.
Brkovich AM, Fisher WA. Psychological distress and infertility: forty years of research. J Psychosom Obstet Gynecol. 1998;4:218–28.CrossRef
11.
Homan GF, Davies M, Norman R. The impact of lifestyle factors on reproductive performance in the general population and those undergoing infertility treatment: a review. Hum Reprod Update. 2007;13:209–23.PubMedCrossRef
12.
Gupta S, Fedor J, Biedenharn K, Agarwal A. Lifestyle factors and oxidative stress in female infertility: is there an evidence base to support the linkage? J Expert Rev Obstet Gynecol. 2013;8:607–24.CrossRef
13.
Domar AD. Psychological stress and infertility. In: Silver JM, Solomon D, editors. Waltham: UpToDate Inc; 2017.
14.
Schmidt L, Holstein BE, Boivin J, Sångren H, Tjørnhøj-Thomsen T, Blaabjerg J, Hald F, Andersen AN, Rasmussen PE. Patients’ attitudes to medical psychosocial aspects of care in infertility clinics: findings from the Copenhagen multi-center psychosocial infertility (COMP1) research Programme. Hum Reprod. 2003;18:628–37.PubMedCrossRef
15.
Gift T, O’M S. Infertility and quality of life: findings from a literature review. Sexually Transmitted Diseases. 2014;41(Suppl 1):115.
16.
Alvarez S, Devouche E. First French national survey on lifestyle and toxic factors in infertile couples. Gynecol Obstet Fertil. 2012;40:765–71.PubMedCrossRef
17.
Wright J, Duchesne C, Sabourin S, Bissonnette F, Benoit J, Girad Y. Psychosocial distress and infertility: men and women respond differently. Fertil Steril. 1991;55:100–8.PubMedCrossRef
18.
Klemetti R, Raitanen J, Sihvo S, Saarni S, Koponen P. Infertility, mental disorders and well-being--a nationwide survey. Acta Obstet Gynecol Scand. 2010;89:677–82.PubMedCrossRef
19.
Henriksen TB. General psychosocial and work-related stress and reduced fertility. Scand J Work Environ Health. 1999;25(Suppl 1):38–9.PubMed
20.
Merari D, Feldberg D, Elizur A, Goldman J, Modan B. Psychological and hormonal changes in the course of in vitro fertilization. J Assist Reprod Genet. 1992;9:161–9.PubMedCrossRef
21.
Harlow CH, Jahy UM, Talbot WM, Wardle PG, Hull MGR. Stress and stress-related hormones during in-vitro fertilization treatment. Hum Reprod. 1996;11:274–9.PubMedCrossRef
22.
Milad MP, Klock SC, Moses S, Chatterton R. Stress and anxiety do not result in pregnancy wastage. Hum Reprod. 1998;13:2296–300.PubMedCrossRef
23.
Sheiner E, Sheiner EK, Potashnik G, Carel R, Shoham-Vardi I. The relationship between occupational psychological stress and female fertility. Occup Med (Lond). 2003;53:265–9.CrossRef
24.
Anderhein L, Holter H, Bergh C, Müller A. Does psychologocal stress affect the outcome of in vitro fertilization? Hum Reprod. 2005;20:2969–75.CrossRef
25.
Cooper BC, Gerber IR, McGettrick AL, Johnson JV. Perceived infertility-related stress correlates with in vitro fertilization outcome. Fertil Steril. 2007;88:714–7.PubMedCrossRef
26.
Griel AL. Infertility and psychological distress: a critical review of literature. Soc Sci Med. 1997;45:1679–704.CrossRef
27.
Wilson JF, Kopitzke EJ. Stress and infertility. Curr Women Health Rep. 2002;2:194–9.
28.
29.
Biringer E, Howard LM, Kessler U, Stewart R, Mykletun A. Is infertility really associated with higher levels of mental distress in the female population? Results from the north-Trøndelag health study and the medical birth registry of Norway. J Psychosom Obstet Gyneacol. 2015;36:38–45.CrossRef
30.
31.
Whirledge S, Cidlowski JA. A role for glucocorticoids in stress-impaired reproduction: beyond the hypothalamus and pituitary. Endocrinology. 2013;154:4450–68.PubMedPubMedCentralCrossRef
32.
33.
34.
Schenker JG, Meirow D, Schenker E. Stress and human reproduction. Eur J Obstet Gynecol Reprod Biol. 1992;16:1–8.CrossRef
35.
Negro-Vilar A. Stress and other environmental factors affecting fertility in men and women: overview. Environ Health Perspect. 1993;101(Suppl 2):59–64.PubMedPubMedCentralCrossRef
36.
Kaufman J, Plotsky PM, Nemeroff CB, Chamey D. Effects of early adverse experiences on brain structure and function: clinical implications. Biol Psychiatry. 2000;48:778–90.CrossRefPubMed
37.
38.
Bablis P, Pollard H, Monti DA. Resolution of anovulation infertility using neuro emotional technique: a report of 3 cases. J Chiropr Med. 2006;5:13–21.PubMedPubMedCentralCrossRef
39.
Sominsky L, Fuller EA, Hodgson DM. Factors in early-life programming of reproductive fitness. Neuroendocrinology. 2015;102:216–25.PubMedCrossRef
40.
Smith SM, Vale WW. The role of the hypothalamicpituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin Neurosci. 2006;8:383–95.PubMedPubMedCentral
41.
Louis GM, Lum KJ, Sundaram R, Chen Z, Kim S, Lynch CD, Schisterman EF, Pyper C. Stress reduces conception probabilities across the fertile window: evidence in support of relaxation. Fertil Steril. 2011;95:2184–9.PubMedCrossRef
42.
Hewagalamulage SD, Clarke IJ, Rao A, Henry BA. Ewes With Divergent Cortisol Responses to ACTH Exhibit Functional Differences in the Hypothalamo-Pituitary-Adrenal (HPA) Axis. Endocrinology. 2016;157:3540–9.PubMedCrossRef
43.
Herod SM, Dettmer AM, Novak MA, Meyer JS, Cameron JL. Sensitivity to stress-induced reproductive dysfunction is associated with a selective but not a generalized increase in activity of the adrenal axis. Am J Physiol Endocrinol Metab. 2011;300:28–36.CrossRef
44.
Campagne DM. Should fertilization treatment start with reducing stress? Hum Reprod. 2006;21:1651–8.PubMedCrossRef
45.
Damti OB, Sarid O, Sheiner E, Zilberstein T, Cwikel J. Stress and distress in infertility among women. Harefuah. 2008;147:256–60.PubMed
46.
Breen KM, Mellon PL. Influence of stress-induced intermediates on gonadotropin gene expression in gonadotrope cells. Mol Cell Endocrinol. 2014;385:71–7.PubMedCrossRef
47.
Geraghty AC, Kaufer D. Glucocorticoid regulation of reproduction. Adv Exp Med Biol. 2015;872:253–78.PubMedCrossRef
48.
Wakodkar V. Stress related infertility and infertility related stress. Indian J Psychiatry. 2017;59(Suppl 2):159.
49.
Pirkalani K, Talaeerad Z. Psychological stress causes relative infertility through direct change in the frequency pattern of GnRH release from the hypothalamus. Eur Psychiatry. 2014;29(Suppl 1):1.
50.
Takumi K, Iijima N, Higo S, Ozawa H. Immunohistochemical analysis of the colocalization of corticotropin-releasing hormone receptor and glucocorticoid receptor in kisspeptin neurons in the hypothalamus of female rats. Neurosci Lett. 2012;531:40–5.PubMedCrossRef
51.
Luo E, Stephens SB, Chaing S, Munaganuru N, Kauffman AS, Breen KM. Corticosterone blocks ovarian cyclicity and the LH surge via decreased kisspeptin neuron activation in female mice. Endocrinology. 2016;157:1187–99.PubMedCrossRef
52.
Ubuka T, Morgan K, Pawson AJ, Osugi T, Chowdhury VS, Minakata H, Tsutsui K, Millar RP, Bentley GE. Identification of human GnIH homologs, RFRP-1 and RFRP-3, and the cognate receptor, GPR147 in the human hypothalamic pituitary axis. PLoS One. 2009;4:e8400.PubMedPubMedCentralCrossRef
53.
Clarke IJ, Bartolini D, Conductier G, Henry BA. Stress increases gonadotropin inhibitory hormone cell activity and input to GnRH cells in ewes. Endocrinology. 2016;157:4339–50.PubMedCrossRef
54.
Kirby ED, Geraghty AC, Ubuka T, Bentley GE, Kaufer D. Stress increases putative gonadotropin inhibitory hormone and decreases luteinizing hormone in male rats. Proc Natl Acad Sci U S A. 2009;106:11324–9.PubMedPubMedCentralCrossRef
55.
Buffet NC, Bouchard P. The neuroendocrine regulation of the human ovarian cycle. Chrobiol Int. 2001;18:893–919.
56.
Monti C, Ciarrocca M, Cardella C, Capozzella A, Rosati MV, Cherubini E, Fargnoli S, Casale T, Tomei F, Tomei G. Exposure to urban stressor and effects on luteinizing hormone (LH) in female outdoor workers. J Environ Sci Helath A Tox Hazard Subst Environ Eng. 2006;41:1437–48.CrossRef
57.
Hjøllund NH, Jensen TK, Bonde JP, Henriksen TB, Andersson AM, Kolstad HA, Ernst E, Giwercman AJ, Skakkebaek NE, Olsen J. Distress and reduced fertility. A follow-up study of first-pregnancy planned. Reprod Endocrinol. 1999;1:47–53.
58.
Smeenk JMJ, Verhaak CM, Aj V, Sweep CG, Jmm M, Sj W. Van Minnen a, Straatman H and Braat DD. Stress and outcome success in IVF: the role of self-reports and endocrine variables. Hum Reprod. 2005;29:991–6.CrossRef
59.
Boivin J, Schmidt L. Infertility-related stress in men and women predicts treatment outcome 1 year later. Fertil Steril. 2005;83:1745–52.PubMedCrossRef
60.
Pal L, Bevilacqua K, Santoro NF. Chronic psychosocial stressors are detrimental to ovarian reserve: a study of infertile women. J Psychosom Obstet Gynaecol. 2010;31:130–9.PubMedCrossRef
61.
Barut MU, Agacayak E, Bozkurt M, Aksu T, Gul T. There is a positive correlation between socioeconomic status and ovarian Reserve in Women of reproductive age. Med Sci Monit. 2016;22:4386–92.PubMedPubMedCentralCrossRef
62.
Kondoh E, Okamoto T, Higuchi T, Tatsumi K, Baba T, Murphy SK, Takakura K, Konishi I, Fujii S. Stress affects uterine receptivity through an ovarian-independent pathway. Hum Reprod. 2009;24:945–53.PubMedCrossRef
63.
Domar AD, Broome A, Zuttermeister PC, Seibel M, Friedman R. The prevalence and predictability of depression in infertile women. Fertil Steril. 1992;58:1158–63.CrossRefPubMed
64.
Nelson CJ, Shindel AW, Naughton CK, Ohebshalom M, Mulhall JP. Prevalence and predictors of sexual problems, relationship stress, and depression in female partners of infertile couples. J Sex Med. 2008;5:1907–14.PubMedCrossRef
65.
Lakatos E, Szabó G, Szigeti FJ, Balog P. Relationships between psychological well-being, lifestyle factors and fertility. Orv Hetil. 2015;156:483–92.PubMedCrossRef
66.
67.
Rooney KL, Domar AD. The impact of stress on fertility treatment. Curr Opin Obstet Gynecol. 2016;28:198–201.PubMedCrossRef
68.
Agarwal A, Aponte-Mellado A, Premkumar BJ, Shaman A, Gupta S. The effects of oxidative stress on female reproduction: a review. Reprod Biol Endocrinol. 2012;29(10):49.CrossRef
69.
70.
Herrmann D, Scherg H, Verres R, von Hagens C, Strowitzki T, Wischmann T. Resilience in infertile couples acts as a protective factor against infertility-specific distress and impaired quality of life. J Assist Reprod Genet. 2011;28:1111–7.PubMedPubMedCentralCrossRef
71.
Jisha PR, Thomas I. Quality of life and infertility: influence of gender, years of marital life, resilience, and anxiety. Psychol Stud. 2016;61:159–69.CrossRef
72.
Domar AD. Stress and infertility in women: is there a relationship? J Clin Psychol. 1996;2:17–27.
73.
Domar AD, Friedman R, Zuttermeister PC. Distress and conception in infertile women: a complementary approach. J Am Med Womens Assoc (1972). 1999;54:196–8.
74.
Domar AD, Clapp D, Slawsby EA, Dusek J, Kessel B, Freizinger M. Impact of group psychological interventions on pregnancy rates in infertile women. Fertil Steril. 2000;73:805–11.PubMedCrossRef
75.
Terzioglu F. Investigation into the effectiveness of counseling on assisted reproductive techniques in Turkey. J Psychosom Obstet Gynaecol. 2001;22:133–41.PubMedCrossRef
76.
Kupka MS, Dorn C, Richter O, Schmutzler A, van der Ven H, Kulczycki A. Stress relief after infertility treatment - spontaneous conception, adoption and psychological counselling. Eur J Obstet Gynecol Reprod Biol. 2003;110:190–5.PubMedCrossRef
77.
Facchinetti F, Tarabusi M, Volpe A. Cognitive-behavioral treatment decreases cardiovascular and neuroendocrine reaction to stress in women waiting for assisted reproduction. Psychoneuroendocrinology. 2004;29:162–73.PubMedCrossRef
78.
Cwikel J, Gidron Y, Sheiner E. Psychological interactions with infertility among women. Eur J Ostet Gynecol Reprod Biol. 2004;117:126–31.CrossRef
79.
de Liz TM, Strauss B. Differential efficacy of group and individual/couple psychotherapy with infertile patients. Hum Reprod. 2005;20:1324–32.PubMedCrossRef
80.
Campagne DM. Stress: at what point in the medical treatment of infertility should it be treated? Papeles del Psicologo. 2008;29:197–204.
81.
Ardakani AM, Chaharsoughi SA. Female Infertility: P-48: Iinfertility and stress. Int J Fertil Steril. 2010;4 Suppl 1.
82.
Oron G, Allnutt E, Lackman T, Sokal-Arnon T, Holzer H, Takefman J. A prospective study using hatha yoga for stress reduction among women waiting for IVF treatment. Reprod BioMed Online. 2015;30:542–8.PubMedCrossRef
83.
Frederiksen Y, Farver-Vestergaard I, Skovgård NG, Ingerslev HJ, Zachariae R. Efficacy of psychosocial interventions for psychological and pregnancy outcomes in infertile women and men: a systematic review and meta-analysis. BMJ Open. 2015;28:e006592.CrossRef
84.
Matthiesen SM, Frederiksen Y, Ingerslev HJ, Zachariae R. Stress, distress and outcome of assisted reproductive technology (ART): a meta-analysis. Hum Reprod. 2011;26:2763–76.PubMedCrossRef
85.
86.
Kitchen H, Aldhouse N, Trigg A, Palencia R, Mitchell S. A review of patient-reported outcome measures to assess female infertility-related quality of life. Health Qual Life Outcomes. 2017;27(15):86.CrossRef
87.
Boivin J, Psychol C, Takefman J, Braverman A. The fertility quality of life (FertiQoL) tool: development and general psychometric properties. Fertil Steril. 2011;96:409–15.PubMedCrossRefPubMedCentral
88.
Moura-Ramos M, Gameiro S, Canavarro MC, Soares I. Assessing infertility stress: re-examining the factor structure of the fertility problem inventory. Hum Reprod. 2012;27:496–505.PubMedCrossRef
89.
Dural O, Yasa C, Keyif B, Celiksoy H, Demiral I, Yuksel Ozgor B, Gungor Ugurlucan F, Bastu E. Effect of infertility on quality of life of women: a validation study of the Turkish FertiQoL. Hum Fertil (Camb). 2016;19:186–91.PubMedCrossRef
90.
91.
Chi HJ, Park IH, Sun HG, Kim JW, Lee KH. Psychological distress and fertility quality of life (FertiQoL) in infertile Korean women: The first validation study of Korean FertiQoL. Clin Exp Reprod Med. 2016;43:174–80.PubMedPubMedCentralCrossRef
92.
Maroufizadeh S, Ghaheri A, Amini P, Samani RO. Psychometric Properties of The Fertility Quality of Life Instrument in Infertile Iranian Women. Int J Fertil Steril. 2017;10:371–9.PubMed
93.
McQuillan J, Stone RAT, Greil AL. Infertility and life satisfaction among women. J Family. 2007;28:955–81.
94.
McQuillan J, Greil AL, White L, Jacob MC. Frustrated fertility: infertility and psychological distress among women. J Marriage Fam. 2003;65:1007–18.CrossRef
95.
Donarelli Z, Lo Coco G, Gullo S, Salerno L, Marino A, Sammartano F, Allegra A. The fertility quality of life questionnaire (FertiQoL) relational subscale: psychometric properties and discriminant validity across gender. Hum Reprod. 2016;31:2061–71.PubMedCrossRef
96.
White L, McQuillan J. No longer intending: the relationship between relinquished fertility intentions and distress. J Marriage Fam. 2006;68:478–90.CrossRef
97.
Jumayev I, Harun-Or-Rashid M, Rustamov O, Zakirova N, Kasuya H, Sakamoto J. Social correlates of female infertility in Uzbekistan. Nagoya J Med Sci. 2012;74:273–83.PubMedPubMedCentral
98.
Andrews FM, Abbey A, Halman LJ. Is fertility-problem stress different? The dynamics of stress in fertile and infertile couples. Fertil Steril. 1992;57:1247–53.PubMedCrossRef
99.
Lo SS, Kok WM. Sexual functioning and quality of life of Hong Kong Chinese women with infertility problem. Hum Fertil (Camb). 2016;19:268–74.CrossRef
100.
Ebbesen SM, Zachariae R, Mehlsen MY, Thomsen D, Højgaard A, Ottosen L, Petersen T, Ingerslev HJ. Stressful life events are associated with a poor in-vitro fertilization (IVF) outcome: a prospective study. Hum Reprod. 2009;24:2173–82.PubMedCrossRef
101.
Santos C, Sobral MP, Martins MV. Effects of life events on infertility diagnosis: comparison with presumably fertile men and women. J Reprod Infant Psychol. 2017;35:1.PubMedCrossRef
102.
Podfigurna-Stopa A, Luisi S, Regini C, Katulski K, Centini G, Meczekalski B, Petraglia F. Mood disorders and quality of life in polycystic ovary syndrome. Gynecol Endocrinol. 2015;31:431–4.PubMedCrossRef
103.
Bahri Khomami M, Rainezani Tehrani F, Azizi F. Infertility and quality of life in women with polycystic ovary syndrome. Iran J Reprod Med. 2015;(Suppl 32–6):32.
104.
Hadjiconstantinou M, Mani H, Patel N, Levy M, Davies M, Khunti K, Stone M. Understanding and supporting women with polycystic ovary syndrome: a qualitative study in an ethnically diverse UK sample. Endocr Connect. 2017;6:323–30.PubMedPubMedCentralCrossRef
105.
106.
Panico A, Messina G, Lupoli GA, Lupoli R, Cacciapuoti M, Moscatelli F, Esposito T, Villano I, Valenzano A, Monda V, Messina A, Precenzano F, Cibelli G, Monda M, Lupoli G. Quality of life in overweight (obese) and normal-weight women with polycystic ovary syndrome. Patient Prefer Adherence. 2017;11:423–9.PubMedPubMedCentralCrossRef
107.
Sendi P, Brunotte R, Potoczna N, Branson R, Horber FF. Health-related quality of life in patients with class II and class III obesity. Obes Surg. 2005;15:1070–6.PubMedCrossRef
108.
Khayata GM, Rizk DE, Hasan MY, Ghazal-Aswad S, Asaad MA. Factors influencing the quality of life of infertile women in United Arab Emirates. Int J Gynaecol Obstet. 2003;80:183–8.PubMedCrossRef
109.
Aliyeh G, Laya F. Quality of life and its correlates among a group of infertile Iranian women. Med Sci Monit. 2007;13:313–7.
110.
Orji EO, Kuti O, Fasubaa OB. Impact of infertility on marital life in Nigeria. Int J Gynaecol Obstet. 2002;79:61–2.PubMedCrossRef
111.
Gameiro S, Boivin J, Dancet E, de Klerk C, Emery M, Lewis-Jones C, Thorn P, Van den Broeck U, Venetis C, Verhaak CM, Wischmann T, Vermeulen N. ESHRE guideline: routine psychosocial care in infertility and medically assisted reproduction-a guide for fertility staff. Hum Reprod. 2015;30:2476–85.PubMedCrossRef
112.
Verhaak CM, Smeenk JMJ, Evers AWM, Kremer JAM, Kraaimaat FW, Braat DDM. Women’s emotional adjustment to IVF: a systematic review of 25 years of research. Hum Reprod Update. 2007;13:27–36.PubMedCrossRef
113.
Knoll N, Schwarzer R, Pfüller B, Kienle R. Transmission of depressive symptoms: a study with couples undergoing assisted-reproduction treatment. Eur Psychol. 2009;14:7–17.CrossRef
114.
115.
Agostini F, Monti F, Paterlini M, Andrei F, Palomba S, La Sala GB. Effect of the previous reproductive outcomes in subfertile women after in vitro fertilization (IVF) and/or intracytoplasmic sperm injection (ICSI) treatments on perinatal anxious and depressive symptomatology. J Psychosom Obstet Gynaecol. 2017;21:1–9.
116.
Domar AD, Gross J, Rooney K, Boivin J. Exploratory randomized trial on the effect of a brief psychological intervention on emotions, quality of life, discontinuation, and pregnancy rates in in vitro fertilization patients. Fert Steril. 2015;104:440–51.CrossRef
117.
118.
An Y, Wang Z, Ji H, Zhang Y, Wu K. Pituitary-adrenal and sympathetic nervous system responses to psychiatric disorders in women undergoing in vitro fertilization treatment. Fertil Steril. 2011;96:404–8.PubMedCrossRef
119.
Csemiczky G, Landgren BM, Collins A. The influence of stress and state anxiety on the outcome of IVF-treatment: psychological and endocrinological assessment of Swedish women entering IVF-treatment. Acta Obstet Gynecol Scand. 2000;79:113–8.PubMedCrossRef
120.
Lynch CD, Sundaram R, Maisog JM, Sweeney AM, Buck Louis GM. Preconception stress increases the risk of infertility: results from a couple-based prospective cohort study--the LIFE study. Hum Reprod. 2014;29:1067–75.PubMedPubMedCentralCrossRef
121.
Luk BHK, Loke AY. The impact of infertility on the psychological well-being, marital relationships, sexual relationships, and quality of life of couples: a systematic review. J Sex Marital Ther. 2015;41:610–25.PubMedCrossRef
122.
Steuber KR, High A. Disclosure strategies, social support, and quality of life in infertile women. Hum Reprod. 2015;30:1635–42.PubMedCrossRef
123.
Aarts JW, Huppelschoten AG, van Empel IW, Boivin J, Verhaak CM, Kremer JA, Nelen WL. How patient-centred care relates to patients’ quality of life and distress: a study in 427 women experiencing infertility. Hum Reprod. 2012;27:488–95.PubMedCrossRef
124.
125.
Taymor ML, Bresnick E. Emotional stress and infertility. Infertility. 1979;2:39–47.PubMed
Metadata
Title
Lifestyle and fertility: the influence of stress and quality of life on female fertility
Authors
Stefano Palomba
Jessica Daolio
Sara Romeo
Francesco Antonino Battaglia
Roberto Marci
Giovanni Battista La Sala
Publication date
01-12-2018
Publisher
BioMed Central
Published in
Reproductive Biology and Endocrinology / Issue 1/2018
Electronic ISSN: 1477-7827
DOI
https://doi.org/10.1186/s12958-018-0434-y

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