Letter to the editor response

Excerpt

On behalf of the original authorship of the paper, “LI-RADS M (LR-M): definite or probably malignancy, not specific for hepatocellular carcinoma,” and the editors of the special edition of Abdominal Radiology on LI-RADS, I would like to respond to the letter to the editor submitted by Drs. Yeun-Yoon Kim, Chansik An, and Myeong-Jin Kim. We thank these investigators for their insightful comments reflecting a broad, international perspective on application of the LI-RADS in practice. As these investigators emphasize, global imaging algorithms variably emphasize sensitivity versus specificity, depending largely on geographic differences in the relative role of deceased donor liver transplantation (DDLT) versus surgical resection or locoregional therapy options for HCC management. We would encourage the authors to publish their experiences with use of LI-RADS to provide peer-reviewed data to inform its future refinement. …