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World Journal of Surgical Oncology
Published in: World Journal of Surgical Oncology 1/2014

Open Access 01-12-2014 | Research

Lesson from 610 liver resections of hepatocellular carcinoma in a single center over 10 years

Authors: Dai Hoon Han, Gi Hong Choi, Jun Yong Park, Sang Hoon Ahn, Kyung Sik Kim, Jin Sub Choi, Kwang-Hyub Han

Published in: World Journal of Surgical Oncology | Issue 1/2014

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Abstract

Background

Recent advances in surgical techniques and perioperative management have led to improved surgical outcomes, especially perioperative outcomes. The aim of this study was to review our experience with hepatic resection for hepatocellular carcinoma (HCC) over a ten-year period to determine how to improve long-term surgical outcomes.

Methods

From January 1996 to December 2007, 610 patients underwent curative resection for HCC at Yonsei University Health System, Seoul, Korea. Prognostic factors for disease-free and overall survival were identified, and surgical outcomes were compared between two time periods: before 2003 and after 2003.

Results

The 1-, 3-, and 5-year overall survival rates were 90.1%, 74.9% and 64.4%, respectively. The patients after 2003 tended to have improved overall survival. The survival rate after recurrence in patients with tumors > 3 cm was significantly greater after 2003. (P = 0.044).

Conclusions

The improved survival rates after 2003 may be explained by better selection of surgical candidates, a reduced perioperative transfusion rate due to improved surgical techniques, and active multimodal treatment for recurrent HCC.
Appendix
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Metadata
Title
Lesson from 610 liver resections of hepatocellular carcinoma in a single center over 10 years
Authors
Dai Hoon Han
Gi Hong Choi
Jun Yong Park
Sang Hoon Ahn
Kyung Sik Kim
Jin Sub Choi
Kwang-Hyub Han
Publication date
01-12-2014
Publisher
BioMed Central
Published in
World Journal of Surgical Oncology / Issue 1/2014
Electronic ISSN: 1477-7819
DOI
https://doi.org/10.1186/1477-7819-12-192

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