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Clinical Neuroradiology
Published in: Clinical Neuroradiology 3/2014

01-09-2014 | Correspondence

Leptomeningeal Carcinomatosis with Involvement of the Cerebellar Hemispheres and the Spinal Cord as First Manifestation of a Metastasizing Breast Carcinoma

Authors: Teodor Catalin Sabou, Peter Kamusella, Reimer Andresen

Published in: Clinical Neuroradiology | Issue 3/2014

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Excerpt

Leptomeningeal invasion is a well-known entity seen in solid tumors or hematological malignancies. The breast and lung cancer as well as melanoma, lymphoma, and leukemia are the most common associated malignancies. The malignant invasion could occur either through inoculation, vasogenic, or direct infiltration if the blood-brain-barrier (BBB) is compromised. …
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Chamberlain MC, Kormanik PR. Carcinomatous meningitis secondary to breast cancer: predictors of response to combined modality therapy. J Neurooncol. 1997;35:55–64.PubMedCrossRef
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Osborne AG, et al. Diagnostic Imaging: Brain. 2nd ed. Lippincott Williams & Wilkins; 2010. Chap. II(3) pp. 36–38, Chap. IV(1) pp. 54–56.
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Pavlidis N. The diagnostic and therapeutic management of leptomeningeal carcinomatosis. Ann Oncol. 2004;15 Suppl 4:iv285–91.PubMed
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Gomori JM, Heching N, Siegal T. Leptomeningeal metastases: evaluation by gadolinium enhanced spinal magnetic resonance imaging. J Neurooncol. 1998;36(1):55–60.PubMedCrossRef
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Collie DA, Brush JP, Lammie GA, Grant R, Kunkler I, Leonard R, et al. Imaging features of leptomeningeal metastases. Clin Radiol. 1999;54(11):765–71.PubMedCrossRef
Metadata
Title
Leptomeningeal Carcinomatosis with Involvement of the Cerebellar Hemispheres and the Spinal Cord as First Manifestation of a Metastasizing Breast Carcinoma
Authors
Teodor Catalin Sabou
Peter Kamusella
Reimer Andresen
Publication date
01-09-2014
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue 3/2014
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-013-0239-5

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