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Annals of Hematology
Published in: Annals of Hematology 9/2009

01-09-2009 | Letter to the Editor

Lenalidomide, as a single agent, induces complete remission in a refractory mantle cell lymphoma

Authors: Adrian Tempescul, Jean-Christophe Ianotto, Frederic Morel, Veronique Marion, Marc De Braekeleer, Christian Berthou

Published in: Annals of Hematology | Issue 9/2009

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Excerpt

Dear Editor, …
Literature
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Campo E, Raffeld M, Jaffe ES (1999) Mantle-cell lymphoma. Semin Hematol 36(2):115–127 (review)PubMed
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Manabe A, Murti KG, Coustan-Smith E, Kumagai M, Behm FG, Raimondi SC, Campana D (1994) Adhesion-dependent survival of normal and leukemic human B lymphoblasts on bone marrow stromal cells. Blood 83(3):758–766PubMed
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Merville P, Déchanet J, Desmoulière A, Durand I, de Bouteiller O, Garrone P, Banchereau J, Liu YJ (1996) −Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts. J Exp Med 183(1):227–236. doi:10.​1084/​jem.​183.​1.​227 PubMedCrossRef
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Corral LG, Haslett PA, Muller GW, Chen R, Wong LM, Ocampo CJ, Patterson RT, Stirling DI, Kaplan G (1999) Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 163(1):380–386PubMed
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Settles B, Stevenson A, Wilson K, Mack C, Ezell T, Davis MF, Taylor LD (2001) Down-regulation of cell adhesion molecules LFA-1 and ICAM-1 after in vitro treatment with the anti-TNF-alpha agent thalidomide. Cell Mol Biol 47(7):1105–1114PubMed
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Kaufmann H, Raderer M, Wöhrer S, Püspök A, Bankier A, Zielinski C, Chott A, Drach J (2004) Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma. Blood 104(8):2269–2271. doi:10.​1182/​blood-2004-03-1091 PubMedCrossRef
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Smith SM, Grinblatt D, Johnson JL, Niedzwiecki D, Rizzieri D, Bartlett NL, Cheson BD, Cancer and Leukemia Group B (2008) Thalidomide has limited single-agent activity in relapsed or refractory indolent non-Hodgkin lymphomas: a phase II trial of the Cancer and Leukemia Group B. Br J Haematol 140(3):313–319. doi:10.​1111/​j.​1365-2141.​2007.​06937.​x PubMedCrossRef
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Wang M, Fayad L, Hegemeister F et al (2007) A phase I/II study of lenalidomide in combination with rituximab in relapsed/refractory mantle cell lymphoma with early evidence of efficacy. J Clin Oncol 25:8030
Metadata
Title
Lenalidomide, as a single agent, induces complete remission in a refractory mantle cell lymphoma
Authors
Adrian Tempescul
Jean-Christophe Ianotto
Frederic Morel
Veronique Marion
Marc De Braekeleer
Christian Berthou
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Annals of Hematology / Issue 9/2009
Print ISSN: 0939-5555
Electronic ISSN: 1432-0584
DOI
https://doi.org/10.1007/s00277-008-0692-4

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