Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2014

Open Access 01-12-2014 | Research article

Left upper lobectomy can be a risk factor for thrombosis in the pulmonary vein stump

Authors: Kazuto Ohtaka, Yasuhiro Hida, Kichizo Kaga, Yasuhiro Takahashi, Hiroshi Kawase, Satoshi Hayama, Tatsunosuke Ichimura, Naoto Senmaru, Naotake Honma, Yoshiro Matsui

Published in: Journal of Cardiothoracic Surgery | Issue 1/2014

Login to get access

Abstract

Background

Thrombosis in the left upper pulmonary vein stump after left upper lobectomy is a very rare but important complication because it occurs in the systemic circulation system. We previously made the first ever report on the frequency and risk factors of thrombosis in the pulmonary vein stump after lobectomy. In this study, we conducted an investigation in a different hospital to determine whether this was a common complication.

Methods

From 2008 to 2012, 151 patients who underwent lobectomy and following enhanced CT within 2 years after the operation were studied. Postoperative contrast-enhanced CT imaging was retrospectively checked.

Results

We found thrombosis in the pulmonary vein stump in 5 of the 151 patients (3.3%). All 5 patients underwent left upper lobectomy (17.9% of the patients who underwent left upper lobectomy). These 5 patients did not have infarction of any vital organ. The thrombus was disappeared several months later on contrast-enhanced CT in 3 patients and followed in 2 patients. On univariate analysis, there was a significant difference only in the operative procedure (p < 0.001).

Conclusions

Thrombosis in the pulmonary vein stump occurred with high frequency in patients who underwent left upper lobectomy. Because the frequency of thrombosis in this study was the same as in our previous report, this might be a common complication.
Appendix
Available only for authorised users
Literature
1.
go back to reference Ohtaka K, Hida Y, Kaga K, Iimura Y, Shiina N, Muto J, Hirano S: Pulmonary vein thrombosis after video-assisted thoracoscopic left upper lobectomy. J Thorac Cardiovasc Surg. 2012, 143: e3-e5. 10.1016/j.jtcvs.2011.09.025.CrossRefPubMed Ohtaka K, Hida Y, Kaga K, Iimura Y, Shiina N, Muto J, Hirano S: Pulmonary vein thrombosis after video-assisted thoracoscopic left upper lobectomy. J Thorac Cardiovasc Surg. 2012, 143: e3-e5. 10.1016/j.jtcvs.2011.09.025.CrossRefPubMed
2.
go back to reference Nagaoka E, Yano M, Sugano T, Miyamoto T: Thrombus in the left superior pulmonary vein after left upper pulmonary lobectomy. J Thorac Cardiovasc Surg. 2008, 135: 709-710. 10.1016/j.jtcvs.2007.11.035.CrossRefPubMed Nagaoka E, Yano M, Sugano T, Miyamoto T: Thrombus in the left superior pulmonary vein after left upper pulmonary lobectomy. J Thorac Cardiovasc Surg. 2008, 135: 709-710. 10.1016/j.jtcvs.2007.11.035.CrossRefPubMed
3.
go back to reference Schwalm S, Ward RP, Spencer KT: Transient ischemic attack in a patient with pulmonary vein thrombosis after left upper lobectomy for squamous cell lung cancer. J Am Soc Echocardiogr. 2004, 17: 487-488. 10.1016/j.echo.2004.02.003.CrossRefPubMed Schwalm S, Ward RP, Spencer KT: Transient ischemic attack in a patient with pulmonary vein thrombosis after left upper lobectomy for squamous cell lung cancer. J Am Soc Echocardiogr. 2004, 17: 487-488. 10.1016/j.echo.2004.02.003.CrossRefPubMed
4.
go back to reference Seki M, Endo M, Kidani M, Kobayashi H, Sato H, Noto T: A rare case of left atrial thrombus after left upper pulmonary lobectomy [Article in Japanese]. Nippon Kyobu Geka Gakkai Zasshi. 1989, 37: 1371-1375.PubMed Seki M, Endo M, Kidani M, Kobayashi H, Sato H, Noto T: A rare case of left atrial thrombus after left upper pulmonary lobectomy [Article in Japanese]. Nippon Kyobu Geka Gakkai Zasshi. 1989, 37: 1371-1375.PubMed
5.
go back to reference Asteriou C, Barbetakis N, Efstathiou A, Kleontas A, Tsilikas C: Renal artery thrombosis following lobectomy for lung cancer. Case Rep Oncol. 2010, 3: 208-211. 10.1159/000314838.CrossRefPubMedPubMedCentral Asteriou C, Barbetakis N, Efstathiou A, Kleontas A, Tsilikas C: Renal artery thrombosis following lobectomy for lung cancer. Case Rep Oncol. 2010, 3: 208-211. 10.1159/000314838.CrossRefPubMedPubMedCentral
6.
go back to reference Oura H, Hirose M, Aikawa H, Ishiki M: Abdominal organ infarction encountered immediately after surgery of primary lung cancer [Article in Japanese]. Kyobu Geka. 2005, 58: 137-142.PubMed Oura H, Hirose M, Aikawa H, Ishiki M: Abdominal organ infarction encountered immediately after surgery of primary lung cancer [Article in Japanese]. Kyobu Geka. 2005, 58: 137-142.PubMed
7.
go back to reference Ohtaka K, Hida Y, Kaga K, Kato T, Muto J, Nakada-Kubota R, Sasaki T, Matsui Y: Thrombosis in the pulmonary vein stump after left upper lobectomy as a possible cause of cerebral infarction. Ann Thorac Surg. 2013, 95: 1924-1928. 10.1016/j.athoracsur.2013.03.005.CrossRefPubMed Ohtaka K, Hida Y, Kaga K, Kato T, Muto J, Nakada-Kubota R, Sasaki T, Matsui Y: Thrombosis in the pulmonary vein stump after left upper lobectomy as a possible cause of cerebral infarction. Ann Thorac Surg. 2013, 95: 1924-1928. 10.1016/j.athoracsur.2013.03.005.CrossRefPubMed
8.
go back to reference Xin Y, Hida Y, Kaga K, Iimura Y, Shiina N, Ohtaka K, Muto J, Kubota S, Matsui Y: Left lobectomy might be a risk factor for atrial fibrillation following pulmonary lobectomy. Eur J Cardiovasc Thorac Surg. 2013, in Press Xin Y, Hida Y, Kaga K, Iimura Y, Shiina N, Ohtaka K, Muto J, Kubota S, Matsui Y: Left lobectomy might be a risk factor for atrial fibrillation following pulmonary lobectomy. Eur J Cardiovasc Thorac Surg. 2013, in Press
9.
go back to reference Kwek BH, Wittram C: Postpneumonectomy pulmonary artery stump thrombosis: CT features and imaging follow-up. Radiology. 2005, 237: 338-341. 10.1148/radiol.2371041686.CrossRefPubMed Kwek BH, Wittram C: Postpneumonectomy pulmonary artery stump thrombosis: CT features and imaging follow-up. Radiology. 2005, 237: 338-341. 10.1148/radiol.2371041686.CrossRefPubMed
10.
go back to reference Rubins J, Unger M, Colice GL: Follow-up and surveillance of the lung cancer patient following curative intent therapy. ACCP evidence-based clinical practice guideline (2nd Edition). Chest. 2007, 132: 355-367. 10.1378/chest.07-1390.CrossRef Rubins J, Unger M, Colice GL: Follow-up and surveillance of the lung cancer patient following curative intent therapy. ACCP evidence-based clinical practice guideline (2nd Edition). Chest. 2007, 132: 355-367. 10.1378/chest.07-1390.CrossRef
Metadata
Title
Left upper lobectomy can be a risk factor for thrombosis in the pulmonary vein stump
Authors
Kazuto Ohtaka
Yasuhiro Hida
Kichizo Kaga
Yasuhiro Takahashi
Hiroshi Kawase
Satoshi Hayama
Tatsunosuke Ichimura
Naoto Senmaru
Naotake Honma
Yoshiro Matsui
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2014
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-9-5

Other articles of this Issue 1/2014

Journal of Cardiothoracic Surgery 1/2014 Go to the issue