Skip to main content
Top
Published in: European Spine Journal 12/2012

01-12-2012 | Original Article

Late infections after dynamic stabilization of the lumbar spine with Dynesys

Authors: Jon A. Lutz, Philippe Otten, Gianluca Maestretti

Published in: European Spine Journal | Issue 12/2012

Login to get access

Abstract

Introduction

Dynamic stabilization of the spine was developed as an alternative to rigid fusion in chronic back pain to reduce the risk of adjacent segment degeneration. Dynamic neutralization system (Dynesys, Zimmer CH) is one of the most popular systems available, but some midterm studies show revision rates as high as 30 %. Some late infectious complications in our patients prompted us to review them systematically. Propionibacterium recently has been shown to cause subtle infections of prosthetic material.

Materials and methods

Here, we report on a consecutive series of 50 Dynesys implants. In a median follow-up of 51 months (range 0–91), we identified 12 infectious and 11 non-infectious complications necessitating reoperation or removal of the implant in 17 patients.

Results

Material infections occurred after a median of 52 months (2–77) and were due to Propionibacterium alone (n = 4) or in combination (n = 3) in seven out of 11 patients. Clinical presentation combines new or increasing pain associated with signs of screw loosening on conventional X-rays; however, as many as 73.5 % of patients present some degree of screw loosening without being at all symptomatic of infection.

Conclusion

The high rate of late infections with low-grade germs and the frequency of screw loosening signs made us suspect a lack of integration at the bone-screw interface. Surgeons should be suspicious if the patient presents a combination of new or increasing pain and signs of screw loosening, and aggressive revision is recommended in these cases.
Literature
1.
go back to reference Beastall J, Karadimas E, Siddiqui M, Nicol M, Hughes J, Smith F, Wardlaw D (2007) The Dynesys lumbar spinal stabilization system: a preliminary report on positional magnetic resonance imaging findings. Spine (Phila Pa 1976) 32:685–690CrossRef Beastall J, Karadimas E, Siddiqui M, Nicol M, Hughes J, Smith F, Wardlaw D (2007) The Dynesys lumbar spinal stabilization system: a preliminary report on positional magnetic resonance imaging findings. Spine (Phila Pa 1976) 32:685–690CrossRef
2.
go back to reference Benezech J, Mitulescu A (2007) Retrospective patient outcome evaluation after semi-rigid stabilization without fusion for degenerative lumbar instability. Eur J Orthop Surg Traumatol 17:227–234CrossRef Benezech J, Mitulescu A (2007) Retrospective patient outcome evaluation after semi-rigid stabilization without fusion for degenerative lumbar instability. Eur J Orthop Surg Traumatol 17:227–234CrossRef
3.
go back to reference Bothmann M, Kast E, Boldt GJ, Oberle J (2008) Dynesys fixation for lumbar spine degeneration. Neurosurg Rev 31:189–196PubMedCrossRef Bothmann M, Kast E, Boldt GJ, Oberle J (2008) Dynesys fixation for lumbar spine degeneration. Neurosurg Rev 31:189–196PubMedCrossRef
4.
go back to reference Collins I, Wilson-MacDonald J, Chami G, Burgoyne W, Vineyakam P, Berendt T, Fairbank J (2008) The diagnosis and management of infection following instrumented spinal fusion. Eur Spine J 17:445–450PubMedCrossRef Collins I, Wilson-MacDonald J, Chami G, Burgoyne W, Vineyakam P, Berendt T, Fairbank J (2008) The diagnosis and management of infection following instrumented spinal fusion. Eur Spine J 17:445–450PubMedCrossRef
5.
go back to reference Dakhil-Jerew F, Jadeja H, Cohen A, Shepperd JAN (2009) Inter-observer reliability of detecting Dynesys pedicle screw using plain X-rays: a study on 50 post-operative patients. Eur Spine J 18:1486–1493PubMedCrossRef Dakhil-Jerew F, Jadeja H, Cohen A, Shepperd JAN (2009) Inter-observer reliability of detecting Dynesys pedicle screw using plain X-rays: a study on 50 post-operative patients. Eur Spine J 18:1486–1493PubMedCrossRef
6.
go back to reference Davis R, Delamarter R, Maxwell J, Welch W, Wingate J, Sherman J (2009) Preliminary 3-year results from a prospective, randomized, controlled IDE study of the Dynesys dynamic stabilization system. In: Abstracts of the 24th annual meeting of the North American spine society, San Francisco, 10–17 Nov 2009, The Spine J, 86S Davis R, Delamarter R, Maxwell J, Welch W, Wingate J, Sherman J (2009) Preliminary 3-year results from a prospective, randomized, controlled IDE study of the Dynesys dynamic stabilization system. In: Abstracts of the 24th annual meeting of the North American spine society, San Francisco, 10–17 Nov 2009, The Spine J, 86S
7.
go back to reference Faundez AA, Schwender JD, Safriel Y, Gilbert ThJ, Mehbod AA, Denis F, Transfeldt EE, Wroblewski JM (2009) Clinical and radiological outcome of anterior-posterior fusion versus trans-foraminal lumbar interbody fusion for symptomatic disc degeneration: a retrospective comparative study of 133 patients. Eur Spine J 18:203–211PubMedCrossRef Faundez AA, Schwender JD, Safriel Y, Gilbert ThJ, Mehbod AA, Denis F, Transfeldt EE, Wroblewski JM (2009) Clinical and radiological outcome of anterior-posterior fusion versus trans-foraminal lumbar interbody fusion for symptomatic disc degeneration: a retrospective comparative study of 133 patients. Eur Spine J 18:203–211PubMedCrossRef
8.
go back to reference Grob D, Benini A, Junge A, Mannion AF (2005) Clinical experience with the Dynesys semirigid fixation system for the lumbar spine. Spine 30:324–331PubMedCrossRef Grob D, Benini A, Junge A, Mannion AF (2005) Clinical experience with the Dynesys semirigid fixation system for the lumbar spine. Spine 30:324–331PubMedCrossRef
9.
go back to reference Lee ChS, Hwang ChJ, Lee SW, Ahn YJ, Kim YT, Lee DH, Lee MY (2009) Risk factors for adjacent segment disease after lumbar fusion. Eur Spine J 18:1637–1643PubMedCrossRef Lee ChS, Hwang ChJ, Lee SW, Ahn YJ, Kim YT, Lee DH, Lee MY (2009) Risk factors for adjacent segment disease after lumbar fusion. Eur Spine J 18:1637–1643PubMedCrossRef
10.
go back to reference Mannion AF, Elfering A (2006) Predictors of surgical outcome and their assessment. Eur Spine J 15:S93–S108PubMedCrossRef Mannion AF, Elfering A (2006) Predictors of surgical outcome and their assessment. Eur Spine J 15:S93–S108PubMedCrossRef
11.
go back to reference Mullholland RC, Sengupta DK (2002) Rationale, principles and experimental evaluation of the concept of soft stabilization. Eur Spine J 11:S198–S205 Mullholland RC, Sengupta DK (2002) Rationale, principles and experimental evaluation of the concept of soft stabilization. Eur Spine J 11:S198–S205
12.
go back to reference Mullholland RC (2008) The myth of lumbar instability: the importance of abnormal loading as a cause of low back pain. Eur Spine J 17:619–625CrossRef Mullholland RC (2008) The myth of lumbar instability: the importance of abnormal loading as a cause of low back pain. Eur Spine J 17:619–625CrossRef
13.
go back to reference Putzier M, Hoff E, Tohtz S, Gross C, Perka C, Strube P (2010) Dynamic stabilization adjacent to single-level fusion: part II. No clinical benefit for asymptomatic, initially degenerated adjacent segments after 6 years follow-up. Eur Spine J 19(12):2181–2189. doi:10.1007/s00586-010-1517-4 PubMedCrossRef Putzier M, Hoff E, Tohtz S, Gross C, Perka C, Strube P (2010) Dynamic stabilization adjacent to single-level fusion: part II. No clinical benefit for asymptomatic, initially degenerated adjacent segments after 6 years follow-up. Eur Spine J 19(12):2181–2189. doi:10.​1007/​s00586-010-1517-4 PubMedCrossRef
14.
go back to reference Reyes-Sánchez A, Zárate-Kalfópulos B, Ramírez-Mora I, Rosales-Olivarez LM, Alpizar-Aguirre A, Sánchez-Bringas G (2010) Posterior dynamic stabilization of the lumbar spine with the Accuflex rod system as a stand-alone device: experience in 20 patients with 2-year follow-up. Eur Spine J. doi:10-1007/s00586-010-1417-7 PubMed Reyes-Sánchez A, Zárate-Kalfópulos B, Ramírez-Mora I, Rosales-Olivarez LM, Alpizar-Aguirre A, Sánchez-Bringas G (2010) Posterior dynamic stabilization of the lumbar spine with the Accuflex rod system as a stand-alone device: experience in 20 patients with 2-year follow-up. Eur Spine J. doi:10-1007/​s00586-010-1417-7 PubMed
15.
go back to reference St Schaeren, Broger I, Jeanneret B (2008) Minimum 4-year follow-up of spinal stenosis with degenerative spondylolisthesis treated with decompression and dynamic stabilization. Spine 33:E636–E642CrossRef St Schaeren, Broger I, Jeanneret B (2008) Minimum 4-year follow-up of spinal stenosis with degenerative spondylolisthesis treated with decompression and dynamic stabilization. Spine 33:E636–E642CrossRef
16.
go back to reference Schimmel JJP, Horsting PP, de Kleuver M, Wonders G, van Limbeck J (2010) Risk factors for deep surgical site infections after spinal fusion. Eur Spine J 19:1711–1719PubMedCrossRef Schimmel JJP, Horsting PP, de Kleuver M, Wonders G, van Limbeck J (2010) Risk factors for deep surgical site infections after spinal fusion. Eur Spine J 19:1711–1719PubMedCrossRef
17.
go back to reference Schwarzenbach O, Berlemann U, Stoll ThM, Dubois G (2005) Posterior dynamic stabilization systems: Dynesys. Orthop Clin N Am 36:363–372CrossRef Schwarzenbach O, Berlemann U, Stoll ThM, Dubois G (2005) Posterior dynamic stabilization systems: Dynesys. Orthop Clin N Am 36:363–372CrossRef
18.
go back to reference Schwarzenbach O, Rohrbach N, Berlemann U (2010) Segment-by-segment stabilization for degenerative disc disease: a hybrid technique. Eur Spine J 19:1010–1020PubMedCrossRef Schwarzenbach O, Rohrbach N, Berlemann U (2010) Segment-by-segment stabilization for degenerative disc disease: a hybrid technique. Eur Spine J 19:1010–1020PubMedCrossRef
19.
go back to reference Stoll ThM, Dubois G, Schwarzenbach O (2002) The dynamic neutralization system for the spine: a multi-center study of a novel non-fusion system. Eur Spine J 11:S170–S178PubMed Stoll ThM, Dubois G, Schwarzenbach O (2002) The dynamic neutralization system for the spine: a multi-center study of a novel non-fusion system. Eur Spine J 11:S170–S178PubMed
20.
go back to reference Strube P, S Tohtz, Hoff E, Gross C, Perka C, Putzier M (2010) Dynamic stabilization adjacent to single-level fusion: part I. Biomechanical effects on lumbar spinal motion. Eur Spine J. doi:10.1007/s00586-010-1549-9 Strube P, S Tohtz, Hoff E, Gross C, Perka C, Putzier M (2010) Dynamic stabilization adjacent to single-level fusion: part I. Biomechanical effects on lumbar spinal motion. Eur Spine J. doi:10.​1007/​s00586-010-1549-9
21.
go back to reference Würgler-Hauri CC, Kalbarczyk A, Wiesli M, Landolt H, Fandino J (2008) Dynamic neutralization of the lumbar spine after microsurgical decompression in acquired lumbar spinal stenosis and segmental instability. Spine 33:E66–E72PubMedCrossRef Würgler-Hauri CC, Kalbarczyk A, Wiesli M, Landolt H, Fandino J (2008) Dynamic neutralization of the lumbar spine after microsurgical decompression in acquired lumbar spinal stenosis and segmental instability. Spine 33:E66–E72PubMedCrossRef
22.
go back to reference Zappe B, Graf S, Ochsner PE, Zimmerli W, Sendi P (2008) Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg 128:1039–1046PubMedCrossRef Zappe B, Graf S, Ochsner PE, Zimmerli W, Sendi P (2008) Propionibacterium spp. in prosthetic joint infections: a diagnostic challenge. Arch Orthop Trauma Surg 128:1039–1046PubMedCrossRef
Metadata
Title
Late infections after dynamic stabilization of the lumbar spine with Dynesys
Authors
Jon A. Lutz
Philippe Otten
Gianluca Maestretti
Publication date
01-12-2012
Publisher
Springer-Verlag
Published in
European Spine Journal / Issue 12/2012
Print ISSN: 0940-6719
Electronic ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2366-0

Other articles of this Issue 12/2012

European Spine Journal 12/2012 Go to the issue