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27-01-2024 | Laser | Mini Review

Subthreshold laser treatment in retinal diseases: a mini review

Authors: Andrzej Grzybowski, Zuzana Sulaviková, Maciej Gawęcki, Igor Kozak

Published in: Graefe's Archive for Clinical and Experimental Ophthalmology

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Abstract

Purpose

To summarize the mechanism and the clinical applications of subthreshold laser (STL) in retinal practice. Subthreshold or “non-destructive” laser includes all types of laser treatments that produce minimal or no damage to the tissues and no visible signs after application.

Methods

A descriptive review of articles from literature databases (PubMed, Medline, Embase, Cochrane, Web of Science) published before August 2023, which discuss current STL treatments of retinal diseases.

Results

This review provides evidence for STL as a treatment option for central serous chorioretinopathy, diabetic retinopathy, age-related macular degeneration, macular edema due to retinal vein occlusion, and other maculopathies. In most published reports, STL has shown a therapeutic effect without damage to the underlying tissue.

Conclusion

Subthreshold laser treatment has shown safety and efficacy in the management of some retinal and macular diseases. Stimulation of the retinal pigment epithelium without destroying adjacent neuroretina has been shown to be sufficient in inducing retinal repair in many clinical cases. Recent research and clinical studies continue to explore the mechanisms and improving therapeutic benefits of this technology as well as extend the range of retinal disorders treatable by this modality.
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Metadata
Title
Subthreshold laser treatment in retinal diseases: a mini review
Authors
Andrzej Grzybowski
Zuzana Sulaviková
Maciej Gawęcki
Igor Kozak
Publication date
27-01-2024
Publisher
Springer Berlin Heidelberg
Published in
Graefe's Archive for Clinical and Experimental Ophthalmology
Print ISSN: 0721-832X
Electronic ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-024-06382-4