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Published in: Clinical Oral Investigations 4/2024

01-04-2024 | Laser | Review

A systematic review and meta-analysis on the effects of phototherapy on postoperative pain in conventional endodontic reintervention

Authors: Larissa Pereira Nunes, Gabriel Pereira Nunes, Túlio Morandin Ferrisse, Henrico Badaoui Strazzi-Sahyon, Eloi Dezan-Júnior, Luciano Tavares Angelo Cintra, Gustavo Sivieri-Araujo

Published in: Clinical Oral Investigations | Issue 4/2024

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Abstract

Objectives

This systematic review and meta-analysis (SRM) aimed to evaluate the efficacy of laser phototherapy (LPT) on the reduction in postoperative pain (PP) of endodontic origin after conventional/non-surgical reintervention of root canals.

Methods

This SRM was registered with PROSPERO (CRD42021243500) and followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. Meta-analysis was conducted using R software with the “META” package, the mean difference (MD) measure of effect was calculated, and the fixed effect model was applied with a 95% confidence interval (CI). The Cochrane collaboration scale was used to assess the risk of bias and the GRADE tool to assess the quality of evidence.

Results

Initially, 1028 articles were found, and five articles were included. Most studies were classified as “low” risk of bias. Of the five clinical studies, four showed a significant decrease in PP after endodontic reintervention in the LPT groups compared to the control group, especially in the first four days after the intervention. In symptomatic teeth with multiple roots, LPT led to less PP at 24 h (MD -0.52 [-1.03; -0.02] p = .04). However, no significant difference between the groups was found at 48 and 72 h (p > .05). The certainty of the evidence was classified as low.

Conclusion

Despite the limitations of this SRM, LPT was shown to be a promising alternative for reducing and controlling PP in conventional endodontic reintervention.

Clinical significance

The use of LPT in endodontic reintervention may be a safe and promising alternative to clinically efficacious agent for use in the management of PP in this procedure.
Appendix
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Metadata
Title
A systematic review and meta-analysis on the effects of phototherapy on postoperative pain in conventional endodontic reintervention
Authors
Larissa Pereira Nunes
Gabriel Pereira Nunes
Túlio Morandin Ferrisse
Henrico Badaoui Strazzi-Sahyon
Eloi Dezan-Júnior
Luciano Tavares Angelo Cintra
Gustavo Sivieri-Araujo
Publication date
01-04-2024
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 4/2024
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-024-05623-4

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