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Published in: Clinical Oral Investigations 1/2021

01-01-2021 | Root Canal Debridement | Review

Effect of intracanal cryotherapy application on postoperative endodontic pain: a systematic review and metaanalysis

Authors: Laise Pena Braga Monteiro, Marcella Yasmin Reis Guerreiro, Roberta de Castro Valino, Marcela Baraúna Magno, Lucianne Cople Maia, Juliana Melo da Silva Brandão

Published in: Clinical Oral Investigations | Issue 1/2021

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Abstract

Objectives

To assess the influence of intracanal cryotherapy application on postoperative pain after endodontic treatment.

Materials and methods

A systematic review (SR) was conducted in seven databases. Articles that were published up to 04 February 2020 were included and randomized clinical trials that used a cold saline solution for final irrigation to manage postoperative endodontic pain were compared with those that used a saline solution at room temperature. Metaanalysis was performed to assess postoperative pain after 6, 24, 48, and 72 h using a random effects model, a confidence interval of 95%, and heterogeneity tested by the I2 index. The certainty of evidence was rated using GRADE.

Results

Qualitative and quantitative analysis included eight and six studies, respectively. Individuals treated with cryotherapy presented lower means of postendodontic pain than the controls, 6 and 24 h after endodontic treatment (MD − 1.30 [− 2.32, − 0.28] p = 0.01 and SMD − 0.68 [ − 1.21, − 0.16] p = 0.01, respectively, with very low certainty of evidence). After 48 and 72 h, both groups demonstrated similar means of postendodontic pain (MD − 0.06 [− 0.18, 0.07] p = 0.38 and SMD − 0.54 [− 1.18, − 0.11] p = 0.10, with high and low certainty of evidence, respectively).

Conclusions

Based on the limited quality evidence, intracanal cryotherapy application reduced postoperative endodontic pain after 6 and 24 h. New clinical trials are needed to support the result of this review.

Clinical significance

This SR provides information about the use of intracanal cryotherapy in clinical practice, guides clinicians to make evidence-based decisions and suggests recommendations for further high-quality studies
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Metadata
Title
Effect of intracanal cryotherapy application on postoperative endodontic pain: a systematic review and metaanalysis
Authors
Laise Pena Braga Monteiro
Marcella Yasmin Reis Guerreiro
Roberta de Castro Valino
Marcela Baraúna Magno
Lucianne Cople Maia
Juliana Melo da Silva Brandão
Publication date
01-01-2021
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 1/2021
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-020-03693-8

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