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Published in: BMC Surgery 1/2021

Open Access 01-12-2021 | Laparotomy | Research article

Risk factors for small bowel obstruction after open rectal cancer resection

Authors: Kevin Afshari, Abbas Chabok, Kenneth Smedh, Maziar Nikberg

Published in: BMC Surgery | Issue 1/2021

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Abstract

Background

Small bowel obstruction (SBO) is observed in around 10% of patients with prior open abdominal surgery. Rectal resection causes the highest readmission rates. The aim of this study was to investigate risk factors for readmission for SBO and causes for SBO in patients who needed surgery following rectal cancer surgery.

Methods

A population-based registry with prospectively gathered data on 752 consecutive patients with rectal cancer who underwent open pelvic surgery between January 1996 and January 2017 was used. Univariable and multivariable regression analysis was performed, and the risk of SBO was assessed.

Results

In total, 84 patients (11%) developed SBO after a median follow-up time of 48 months. Of these patients, 57% developed SBO during the 1st year after rectal cancer surgery. Surgery for SBO was performed in 32 patients (4.3%), and the cause of SBO was stoma-related in one-fourth of these patients. In the univariable analysis previous RT and re-laparotomy were found as risk factors for readmission for SBO. Re-laparotomy was an independent risk factor for readmission for SBO (OR 2.824, CI 1.129–7.065, P = 0.026) in the multivariable analysis, but not for surgery for SBO. Rectal resection without anastomoses, splenic flexors mobilization, intraoperative bleeding, operative time were not found as risk factors for SBO.

Conclusions

One-tenth of rectal cancer patients who had open surgery developed SBO, most commonly within the 1st postoperative year. The risk of SBO is greatest in patients with complications after rectal cancer resection that result in a re-laparotomy.
Literature
1.
go back to reference Menzies D, Ellis H. Intestinal obstruction from adhesions—how big is the problem? Ann R Coll Surg Engl. 1990;72(1):60–3.PubMedPubMedCentral Menzies D, Ellis H. Intestinal obstruction from adhesions—how big is the problem? Ann R Coll Surg Engl. 1990;72(1):60–3.PubMedPubMedCentral
2.
go back to reference Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl. 1993;75(3):147–53.PubMedPubMedCentral Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl. 1993;75(3):147–53.PubMedPubMedCentral
3.
go back to reference Hershlag A, Diamond MP, DeCherney AH. Adhesiolysis. Clin Obstet Gynecol. 1991;34(2):395–402.CrossRef Hershlag A, Diamond MP, DeCherney AH. Adhesiolysis. Clin Obstet Gynecol. 1991;34(2):395–402.CrossRef
4.
go back to reference Rapkin AJ. Adhesions and pelvic pain: a retrospective study. Obstet Gynecol. 1986;68(1):13–5.PubMed Rapkin AJ. Adhesions and pelvic pain: a retrospective study. Obstet Gynecol. 1986;68(1):13–5.PubMed
5.
go back to reference ten Broek RP, Issa Y, van Santbrink EJ, Bouvy ND, Kruitwagen RF, Jeekel J, et al. Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis. BMJ. 2013;347:f5588.CrossRef ten Broek RP, Issa Y, van Santbrink EJ, Bouvy ND, Kruitwagen RF, Jeekel J, et al. Burden of adhesions in abdominal and pelvic surgery: systematic review and met-analysis. BMJ. 2013;347:f5588.CrossRef
6.
go back to reference Parker MC, Ellis H, Moran BJ, Thompson JN, Wilson MS, Menzies D, et al. Postoperative adhesions: ten-year follow-up of 12,584 patients undergoing lower abdominal surgery. Dis Colon Rectum. 2001;44(6):822–9 (discussion 9-30).CrossRef Parker MC, Ellis H, Moran BJ, Thompson JN, Wilson MS, Menzies D, et al. Postoperative adhesions: ten-year follow-up of 12,584 patients undergoing lower abdominal surgery. Dis Colon Rectum. 2001;44(6):822–9 (discussion 9-30).CrossRef
7.
go back to reference Ellis H, Moran BJ, Thompson JN, Parker MC, Wilson MS, Menzies D, et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet. 1999;353(9163):1476–80.CrossRef Ellis H, Moran BJ, Thompson JN, Parker MC, Wilson MS, Menzies D, et al. Adhesion-related hospital readmissions after abdominal and pelvic surgery: a retrospective cohort study. Lancet. 1999;353(9163):1476–80.CrossRef
8.
go back to reference Parker MC, Wilson MS, Menzies D, Sunderland G, Clark DN, Knight AD, et al. The SCAR-3 study: 5-year adhesion-related readmission risk following lower abdominal surgical procedures. Colorectal Dis. 2005;7(6):551–8.CrossRef Parker MC, Wilson MS, Menzies D, Sunderland G, Clark DN, Knight AD, et al. The SCAR-3 study: 5-year adhesion-related readmission risk following lower abdominal surgical procedures. Colorectal Dis. 2005;7(6):551–8.CrossRef
9.
go back to reference Angenete E, Jacobsson A, Gellerstedt M, Haglind E. Effect of laparoscopy on the risk of small-bowel obstruction: a population-based register study. Arch Surg. 2012;147(4):359–65.CrossRef Angenete E, Jacobsson A, Gellerstedt M, Haglind E. Effect of laparoscopy on the risk of small-bowel obstruction: a population-based register study. Arch Surg. 2012;147(4):359–65.CrossRef
10.
go back to reference Menzies D, Parker M, Hoare R, Knight A. Small bowel obstruction due to postoperative adhesions: treatment patterns and associated costs in 110 hospital admissions. Ann R Coll Surg Engl. 2001;83(1):40–6.PubMedPubMedCentral Menzies D, Parker M, Hoare R, Knight A. Small bowel obstruction due to postoperative adhesions: treatment patterns and associated costs in 110 hospital admissions. Ann R Coll Surg Engl. 2001;83(1):40–6.PubMedPubMedCentral
11.
go back to reference Wysocki A, Pozniczek M, Kulawik J, Krzywon J. Peritoneal adhesions as cause of small bowel obstruction. Przegl Lek. 2003;60(Suppl 7):32–5.PubMed Wysocki A, Pozniczek M, Kulawik J, Krzywon J. Peritoneal adhesions as cause of small bowel obstruction. Przegl Lek. 2003;60(Suppl 7):32–5.PubMed
12.
go back to reference Van Der Krabben AA, Dijkstra FR, Nieuwenhuijzen M, Reijnen MM, Schaapveld M, Van Goor H. Morbidity and mortality of inadvertent enterotomy during adhesiotomy. Br J Surg. 2000;87(4):467–71.CrossRef Van Der Krabben AA, Dijkstra FR, Nieuwenhuijzen M, Reijnen MM, Schaapveld M, Van Goor H. Morbidity and mortality of inadvertent enterotomy during adhesiotomy. Br J Surg. 2000;87(4):467–71.CrossRef
13.
go back to reference Blok RD, Musters GD, Borstlap WAA, Buskens CJ, Bemelman WA, Tanis PJ, et al. Snapshot study on the value of omentoplasty in abdominoperineal resection with primary perineal closure for rectal cancer. Ann Surg Oncol. 2018;25(3):729–36.CrossRef Blok RD, Musters GD, Borstlap WAA, Buskens CJ, Bemelman WA, Tanis PJ, et al. Snapshot study on the value of omentoplasty in abdominoperineal resection with primary perineal closure for rectal cancer. Ann Surg Oncol. 2018;25(3):729–36.CrossRef
14.
go back to reference Nikberg M, Kindler C, Chabok A, Letocha H, Shetye J, Smedh K. Circumferential resection margin as a prognostic marker in the modern multidisciplinary management of rectal cancer. Dis Colon Rectum. 2015;58(3):275–82.CrossRef Nikberg M, Kindler C, Chabok A, Letocha H, Shetye J, Smedh K. Circumferential resection margin as a prognostic marker in the modern multidisciplinary management of rectal cancer. Dis Colon Rectum. 2015;58(3):275–82.CrossRef
15.
go back to reference Khani MH, Smedh K, Kraaz W. Is the circumferential resection margin a predictor of local recurrence after preoperative radiotherapy and optimal surgery for rectal carcinoma? Colorectal Dis. 2007;9(8):706–12.CrossRef Khani MH, Smedh K, Kraaz W. Is the circumferential resection margin a predictor of local recurrence after preoperative radiotherapy and optimal surgery for rectal carcinoma? Colorectal Dis. 2007;9(8):706–12.CrossRef
16.
go back to reference Andersen P, Jensen KK, Erichsen R, Froslev T, Krarup PM, Madsen MR, et al. Nationwide population-based cohort study to assess risk of surgery for adhesive small bowel obstruction following open or laparoscopic rectal cancer resection. BJS Open. 2017;1(2):30–8.CrossRef Andersen P, Jensen KK, Erichsen R, Froslev T, Krarup PM, Madsen MR, et al. Nationwide population-based cohort study to assess risk of surgery for adhesive small bowel obstruction following open or laparoscopic rectal cancer resection. BJS Open. 2017;1(2):30–8.CrossRef
17.
go back to reference Yang KM, Yu CS, Lee JL, Kim CW, Yoon YS, Park IJ, et al. The long-term outcomes of recurrent adhesive small bowel obstruction after colorectal cancer surgery favor surgical management. Medicine (Baltimore). 2017;96(43):e8316.CrossRef Yang KM, Yu CS, Lee JL, Kim CW, Yoon YS, Park IJ, et al. The long-term outcomes of recurrent adhesive small bowel obstruction after colorectal cancer surgery favor surgical management. Medicine (Baltimore). 2017;96(43):e8316.CrossRef
18.
go back to reference Edna TH, Bjerkeset T. Small bowel obstruction in patients previously operated on for colorectal cancer. Eur J Surg. 1998;164(8):587–92.CrossRef Edna TH, Bjerkeset T. Small bowel obstruction in patients previously operated on for colorectal cancer. Eur J Surg. 1998;164(8):587–92.CrossRef
19.
go back to reference Gadan S, Floodeen H, Lindgren R, Matthiessen P. Does a defunctioning stoma impair anorectal function after low anterior resection of the rectum for cancer? A 12-year follow-up of a randomized multicenter trial. Dis Colon Rectum. 2017;60(8):800–6.CrossRef Gadan S, Floodeen H, Lindgren R, Matthiessen P. Does a defunctioning stoma impair anorectal function after low anterior resection of the rectum for cancer? A 12-year follow-up of a randomized multicenter trial. Dis Colon Rectum. 2017;60(8):800–6.CrossRef
20.
go back to reference Park J, Angenete E, Bock D, Correa-Marinez A, Danielsen AK, Gehrman J, et al. Cost analysis in a randomized trial of early closure of a temporary ileostomy after rectal resection for cancer (EASY trial). Surg Endosc. 2019;34:69–76.CrossRef Park J, Angenete E, Bock D, Correa-Marinez A, Danielsen AK, Gehrman J, et al. Cost analysis in a randomized trial of early closure of a temporary ileostomy after rectal resection for cancer (EASY trial). Surg Endosc. 2019;34:69–76.CrossRef
21.
go back to reference Smolarek S, Shalaby M, Paolo Angelucci G, Missori G, Capuano I, Franceschilli L, et al. Small-bowel obstruction secondary to adhesions after open or laparoscopic colorectal surgery. JSLS. 2016;20(4). Smolarek S, Shalaby M, Paolo Angelucci G, Missori G, Capuano I, Franceschilli L, et al. Small-bowel obstruction secondary to adhesions after open or laparoscopic colorectal surgery. JSLS. 2016;20(4).
22.
go back to reference Birgisson H, Pahlman L, Gunnarsson U, Glimelius B, Swedish Rectal Cancer Trial G. Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol. 2005;23(34):8697–705.CrossRef Birgisson H, Pahlman L, Gunnarsson U, Glimelius B, Swedish Rectal Cancer Trial G. Adverse effects of preoperative radiation therapy for rectal cancer: long-term follow-up of the Swedish Rectal Cancer Trial. J Clin Oncol. 2005;23(34):8697–705.CrossRef
23.
go back to reference Peeters KC, van de Velde CJ, Leer JW, Martijn H, Junggeburt JM, Kranenbarg EK, et al. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients—a Dutch colorectal cancer group study. J Clin Oncol. 2005;23(25):6199–206.CrossRef Peeters KC, van de Velde CJ, Leer JW, Martijn H, Junggeburt JM, Kranenbarg EK, et al. Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients—a Dutch colorectal cancer group study. J Clin Oncol. 2005;23(25):6199–206.CrossRef
Metadata
Title
Risk factors for small bowel obstruction after open rectal cancer resection
Authors
Kevin Afshari
Abbas Chabok
Kenneth Smedh
Maziar Nikberg
Publication date
01-12-2021
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2021
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-021-01072-y

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