Top

Published in:

01-05-2022 | Literatur kommentiert

Körperstereotaktische Bestrahlung als „Erstlinientherapie“ des oligometastasierten Nierenzellkarzinoms

Author: Prof. Dr. med. Matthias Guckenberger, MD

Published in: Strahlentherapie und Onkologie | Issue 5/2022

Auszug

Die aktuelle Studie untersuchte, ob bei Patienten mit oligometastasiertem Nierenzellkarzinom eine Bestrahlung aller Metastasen machbar ist und ob durch eine „first-line“ lokale Strahlentherapie der Beginn einer palliativen systemischen Therapie hinausgezögert werden kann. …

Siva S et al (2018) Pooled analysis of stereotactic ablative radiotherapy for primary renal cell carcinoma: a report from the International Radiosurgery Oncology Consortium for Kidney (IROCK): pooled analysis of SABR for primary RCC. Cancer 124:934–942CrossRef

Hoerner-Rieber J et al (2017) Stereotactic body radiotherapy (SBRT) for pulmonary metastases from renal cell carcinoma‑a multicenter analysis of the German working group “Stereotactic Radiotherapy”. J Thorac Dis 9:4512–4522CrossRef

Kroeze SGC et al (2021) Stereotactic radiotherapy combined with immunotherapy or targeted therapy for metastatic renal cell carcinoma. BJU Int 127:703–711CrossRef

Sheehan JP, Sun M‑H, Kondziolka D, Flickinger J, Lunsford LD (2003) Radiosurgery in patients with renal cell carcinoma metastasis to the brain: long-term outcomes and prognostic factors influencing survival and local tumor control. J Neurosurg 98:342–349CrossRef

Palma DA et al (2019) Measuring the integration of stereotactic ablative radiotherapy plus surgery for early-stage non-small cell lung cancer: a phase 2 clinical trial. JAMA Oncol. https://doi.org/10.1001/jamaoncol.2018.6993CrossRefPubMedPubMedCentral

Chang JY et al (2021) Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery. Lancet Oncol 22:1448–1457CrossRef

Aeppli S et al (2021) First-line treatment of metastatic clear cell renal cell carcinoma: a decision-making analysis among experts. ESMO Open 6(1):100030CrossRef

Motzer RJ et al (2018) Nivolumab plus ipilimumab versus sunitinib in advanced renal-cell carcinoma. N Engl J Med 378:1277–1290CrossRef

Rini BI et al (2019) Pembrolizumab plus axitinib versus sunitinib for advanced renal-cell carcinoma. N Engl J Med. https://doi.org/10.1056/NEJMoa1816714CrossRefPubMedPubMedCentral

10.

Zhang Y et al (2019) Stereotactic ablative radiation therapy (SAbR) used to defer systemic therapy in oligometastatic renal cell cancer. Int J Radiat Oncol 105:367–375CrossRef

11.

Rini BI et al (2016) Active surveillance in metastatic renal-cell carcinoma: a prospective, phase 2 trial. Lancet Oncol 17:1317–1324CrossRef

12.

Harrison MR et al (2021) Active surveillance of metastatic renal cell carcinoma: results from a prospective observational study (MaRCC). Cancer 127:2204–2212CrossRef

13.

Corradini S et al (2019) MR-guidance in clinical reality: current treatment challenges and future perspectives. Radiat Oncol 14:92CrossRef

14.

Siva S et al (2021) Stereotactic radiotherapy and short-course pembrolizumab for oligometastatic renal cell carcinoma—the RAPPORT trial. Eur Urol. https://doi.org/10.1016/j.eururo.2021.12.006CrossRefPubMed

Title: Körperstereotaktische Bestrahlung als „Erstlinientherapie“ des oligometastasierten Nierenzellkarzinoms
Author: Prof. Dr. med. Matthias Guckenberger, MD
Publication date: 01-05-2022
Publisher: Springer Berlin Heidelberg
Published in: Strahlentherapie und Onkologie / Issue 5/2022
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI: https://doi.org/10.1007/s00066-022-01920-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Körperstereotaktische Bestrahlung als „Erstlinientherapie“ des oligometastasierten Nierenzellkarzinoms

Auszug

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Auszug

Please log in to get access to this content

Other articles of this Issue 5/2022

Survival outcomes, hematologic complications and growth impairment after sequential chemoradiotherapy in intracranial NGGCTs: a retrospective study

Chasing a rarity: a retrospective single-center evaluation of prognostic factors in primary gliosarcoma

Single-isocenter stereotactic non-coplanar arc treatment of 200 patients with brain metastases: multileaf collimator size and setup uncertainties

Association between treatment-related lymphopenia and survival in glioblastoma patients following postoperative chemoradiotherapy

Deutlicher Überlebensvorteil durch simultane Radio- und Chemotherapie: Erkenntnisse aus einer chinesischen Phase-III-Studie bei älteren Patienten mit Ösophaguskarzinom

Diffusion tensor imaging indices as biomarkers for cognitive changes following paediatric radiotherapy: a systematic review and meta-analysis