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BMC Musculoskeletal Disorders

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Open Access 01-12-2022 | Knee Osteoarthritis | Research article

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Authors: Yaqi Zong, Congqiang Hao, Yingjian Zhang, Shuwen Wu

Published in: BMC Musculoskeletal Disorders | Issue 1/2022

Abstract

Background

The number of Parkinson’s patients (PD) undergoing total knee arthroplasty (TKA) is increasing. The purpose of the study was to characterize quality of life (QOL) outcomes for patients with coexisting PD and knee osteoarthritis (KOA) following TKA.

Methods

Patients with coexisting PD and KOA undergoing TKA between June 2014 and June 2020 were included. These patients were matched to controls with KOA alone by age, gender, basic social background information and Knee society score (KSS). The primary measure was to assess the QOL by the absolute changes in the EuroQOL5-Dimensions (EQ-5D), Pain and Disability Questionnaire (PDQ), and Patient Health Questionnaire-9(PHQ-9) at the last follow-up (LFU). Secondary measures were changes in QOL that exceeded the minimum clinically important difference value (MCID). Data on the health status and QOL of all patients were collected. Simple and multivariate regression analysis was used to evaluate the impact of PD on their QOL.

Results

Twelve KOA patients with PD were compared with 48 controls. Control patients experienced QOL improvement across all three measures:EQ-5D index (0.545–0.717, P < 0.01), PDQ (81.1–52.3, P < 0.01) and PHQ-9(8.22–5.91, P < 0.01) were significantly improved at the LFU; while in patients with PD, only PDQ (91.0–81.4, P = 0.03) slightly improved. There were significant differences in the improvement of QOL between PD patients and the control group through EQ-5D (0.531 vs.0.717, P < 0.01) and PDQ (81.4vs.52.3, P < 0.01) at the LFU.

Conclusion

TKA has no benefit of QOL beyond a slight improvement in pain-related disability in the KOA patients with PD.

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Title: Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease
Authors: Yaqi Zong
Congqiang Hao
Yingjian Zhang
Shuwen Wu
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Knee Osteoarthritis
Parkinson's Disease
Knee Osteoarthritis
Published in: BMC Musculoskeletal Disorders / Issue 1/2022
Electronic ISSN: 1471-2474
DOI: https://doi.org/10.1186/s12891-022-05176-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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