Skip to main content
Top
Published in: Journal of Nuclear Cardiology 6/2022

25-05-2021 | Kidney Transplantation | Editorial

Perioperative cardiac risk assessment in kidney transplantation: It’s time to search for a new gold standard

Authors: Yasmeen Golzar, MD, Rami Doukky, MD, MSc, MBA, FASNC

Published in: Journal of Nuclear Cardiology | Issue 6/2022

Login to get access

Excerpt

Increased cardiac risk associated with advanced chronic kidney disease (CKD) poses a particular challenge when evaluating candidates for renal transplantation. The incidence of myocardial infarction (MI) in renal transplant candidates is considerable, ranging 8.7%-16.7% by 3 years after transplant listing and 4.7%-11.1% after transplantation.1 Alarmingly, almost half of the deaths that occur within 30 days after kidney transplantation are due to MI.2 With little data to help guide cardiac risk stratification and even fewer tools to mitigate that risk, not only do transplant teams have to contend with a challenging peri-transplant period, they must also grapple with how to ethically, yet prudently allocate scarce donor organs in an extraordinarily high-risk patient population. …
Literature
1.
go back to reference Manoushagian S, Meshkov A. Evaluation of solid organ transplant candidates for coronary artery disease. Am J Transplant 2014; 14:2228-34CrossRef Manoushagian S, Meshkov A. Evaluation of solid organ transplant candidates for coronary artery disease. Am J Transplant 2014; 14:2228-34CrossRef
2.
go back to reference Knoll G, Cockfield S, Blydt-Hansen T, Baran D, Kiberd B, Landsberg D et al. Canadian Society of Transplantation consensus guidelines on eligibility for kidney transplantation. CMAJ 2005; 173:1181-84CrossRef Knoll G, Cockfield S, Blydt-Hansen T, Baran D, Kiberd B, Landsberg D et al. Canadian Society of Transplantation consensus guidelines on eligibility for kidney transplantation. CMAJ 2005; 173:1181-84CrossRef
3.
go back to reference Wang LW, Fahim MA, Hayen A, Mitchell RL, Lord SW, Baines LA et al. Cardiac testing for coronary artery disease in potential kidney transplant recipients: A systematic review of test accuracy studies. Am J Kidney Dis 2011; 57:476-87CrossRef Wang LW, Fahim MA, Hayen A, Mitchell RL, Lord SW, Baines LA et al. Cardiac testing for coronary artery disease in potential kidney transplant recipients: A systematic review of test accuracy studies. Am J Kidney Dis 2011; 57:476-87CrossRef
4.
go back to reference Doukky R, Fughhi I, Campagnoli T, Wassouf M, Kharouta M, Vij A et al. Validation of a clinical pathway to assess asymptomatic renal transplant candidates using myocardial perfusion imaging. J Nucl Cardiol 2018; 25:2058-68CrossRef Doukky R, Fughhi I, Campagnoli T, Wassouf M, Kharouta M, Vij A et al. Validation of a clinical pathway to assess asymptomatic renal transplant candidates using myocardial perfusion imaging. J Nucl Cardiol 2018; 25:2058-68CrossRef
5.
go back to reference Golzar Y, Doukky R. Stress SPECT myocardial perfusion imaging in end-stage renal disease. Curr Cardiovasc Imaging Rep 2017; 10:1-13CrossRef Golzar Y, Doukky R. Stress SPECT myocardial perfusion imaging in end-stage renal disease. Curr Cardiovasc Imaging Rep 2017; 10:1-13CrossRef
6.
go back to reference Vij A, Golzar Y, Doukky R. Regadenoson use in chronic kidney disease and end-stage renal disease: A focused review. J Nucl Cardiol 2018; 25:137–49 CrossRef Vij A, Golzar Y, Doukky R. Regadenoson use in chronic kidney disease and end-stage renal disease: A focused review. J Nucl Cardiol 2018; 25:137–49 CrossRef
7.
go back to reference Doukky R, Fughhi I, Campagnoli T, Wassouf M, Ali A. The prognostic value of regadenoson SPECT myocardial perfusion imaging in patients with end-stage renal disease. J Nucl Cardiol 2017; 24:112–8CrossRef Doukky R, Fughhi I, Campagnoli T, Wassouf M, Ali A. The prognostic value of regadenoson SPECT myocardial perfusion imaging in patients with end-stage renal disease. J Nucl Cardiol 2017; 24:112–8CrossRef
12.
go back to reference Parikh K, Appis A, Doukky R. Cardiac imaging for the assessment of patients being evaluated for kidney or liver transplantation. J Nucl Cardiol 2015; 22:282-96CrossRef Parikh K, Appis A, Doukky R. Cardiac imaging for the assessment of patients being evaluated for kidney or liver transplantation. J Nucl Cardiol 2015; 22:282-96CrossRef
13.
go back to reference Lentine KL, Costa SP, Weir MR, Robb JF, Fleisher LA, Kasiske BL et al. Cardiac disease evaluation and management among kidney and liver transplantation candidates: A scientific statement from the American Heart Association and the American College of Cardiology Foundation. J Am Coll Cardiol 2012; 60:434-80CrossRef Lentine KL, Costa SP, Weir MR, Robb JF, Fleisher LA, Kasiske BL et al. Cardiac disease evaluation and management among kidney and liver transplantation candidates: A scientific statement from the American Heart Association and the American College of Cardiology Foundation. J Am Coll Cardiol 2012; 60:434-80CrossRef
14.
go back to reference Shah NR, Charytan DM, Murthy VL, Skali Lami H, Veeranna V, Cheezum MK et al. Prognostic value of coronary flow reserve in patients with dialysis-dependent ESRD. J Am Soc Nephrol 2016; 27:1823-29CrossRef Shah NR, Charytan DM, Murthy VL, Skali Lami H, Veeranna V, Cheezum MK et al. Prognostic value of coronary flow reserve in patients with dialysis-dependent ESRD. J Am Soc Nephrol 2016; 27:1823-29CrossRef
15.
go back to reference Murthy VL, Naya M, Foster CR, Hainer J, Gaber M, Dorbala S et al. Coronary vascular dysfunction and prognosis in patients with chronic kidney disease. JACC Cardiovasc Imaging 2012; 5:1025-34CrossRef Murthy VL, Naya M, Foster CR, Hainer J, Gaber M, Dorbala S et al. Coronary vascular dysfunction and prognosis in patients with chronic kidney disease. JACC Cardiovasc Imaging 2012; 5:1025-34CrossRef
Metadata
Title
Perioperative cardiac risk assessment in kidney transplantation: It’s time to search for a new gold standard
Authors
Yasmeen Golzar, MD
Rami Doukky, MD, MSc, MBA, FASNC
Publication date
25-05-2021
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 6/2022
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-021-02673-z

Other articles of this Issue 6/2022

Journal of Nuclear Cardiology 6/2022 Go to the issue