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Open Access 21-08-2023 | Keratectomy | REVIEW

Management of Corneal Haze After Photorefractive Keratectomy

Authors: Majid Moshirfar, Qiancheng Wang, Joshua Theis, Kaiden C. Porter, Isabella M. Stoakes, Carter J. Payne, Phillip C. Hoopes

Published in: Ophthalmology and Therapy | Issue 6/2023

Abstract

Photorefractive keratectomy (PRK) is a safe and popular corneal surgery performed worldwide. Nevertheless, there is potential risk of corneal haze development after surgery. Proper management of post PRK haze is important for good visual outcome. We performed a comprehensive review of the literature on the various risk factors and treatments for PRK haze, searching the PubMed, Google Scholar, SCOPUS, ScienceDirect, and Embase databases using relevant search terms. All articles in English from August 1989 through April 2023 were reviewed for this study, among which 102 articles were chosen to be included in the study. Depending on the characteristics of and examination findings on post PRK haze, different management options may be preferred. In the proposed framework, management of PRK haze should include a full workup that includes patient’s subjective complaints and loss of vision as well as visual acuity, biomicroscopy, anterior segment optical coherence tomography, epithelial mapping, and Scheimpflug densitometry. Topical steroid treatment for haze should be stratified based on early- or late-onset haze. Mechanical debridement or superficial phototherapeutic keratectomy (PTK) may be used to treat superficial corneal haze. Deep PTK and/or PRK can be used to treat deep corneal haze. Mitomycin-C and topical steroids are prophylactic post-surgery agents to prevent recurrence of haze.

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Title: Management of Corneal Haze After Photorefractive Keratectomy
Authors: Majid Moshirfar
Qiancheng Wang
Joshua Theis
Kaiden C. Porter
Isabella M. Stoakes
Carter J. Payne
Phillip C. Hoopes
Publication date: 21-08-2023
Publisher: Springer Healthcare
Keywords: Keratectomy
Wound Debridement
Published in: Ophthalmology and Therapy / Issue 6/2023
Print ISSN: 2193-8245
Electronic ISSN: 2193-6528
DOI: https://doi.org/10.1007/s40123-023-00782-1

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