Published in:
01-01-2016 | Original Article
Juvenile idiopathic arthritis activity and function ability: deleterious effects in periodontal disease?
Authors:
Camila Pugliese, Roberta T. A. van der Vinne, Lucia M. A. Campos, Priscila R. Guardieiro, Cynthia Saviolli, Eloisa Bonfá, Rosa M. R. Pereira, Vilma S. Viana, Eduardo F. Borba, Clovis A. Silva
Published in:
Clinical Rheumatology
|
Issue 1/2016
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Abstract
The impact of juvenile idiopathic arthritis (JIA) in periodontal diseases is controversial probably due to gender and age heterogeneity. We therefore evaluated a homogeneous female post-pubertal JIA population for these conditions. Thirty-five JIA patients and 35 gender/age comparable healthy controls were evaluated according to demographic data, complete periodontal evaluation, fasting lipoproteins, and anti-lipoprotein lipase antibodies. JIA scores, laboratorial tests, X-rays, and treatment were also assessed. Current age was similar in JIA patients and controls (11.90 ± 2.0 vs. 12.50 ± 3.0 years, p = 0.289). Complete periodontal assessments revealed that gingival index, dental plaque, gingival bleeding, and clinical dental attachment indices were alike in JIA patients and controls (p > 0.05), except for gingival enlargement in former group (p < 0.0001). Further analysis of patients with and without gingivitis revealed that cyclosporine use was more often observed in JIA patients with gingivitis (37 vs. 0 %, p = 0.01), whereas no differences were evidenced in demographic, JIA scores, inflammatory markers, and lipid profile in both groups. Of note, two parameters of periodontal assessment were correlated with JIA scores [gingival index (GI) and Childhood Health Assessment Questionnaire (CHAQ) (r
s
= +0.402, p = 0.020)] and plaque index (PI) and visual analog scale (VAS) physician (r
s
= +0.430, p = 0.013). In addition, evaluation of dental assessment demonstrated that JIA activity scores had positive correlation with decayed, missing, and filled teeth (DMF-T) and junvenile athritis disease activity score (JADAS) (r
s
= +0.364,p = 0.037), VAS physician (r
s
= +0.401,p = 0.021) and VAS patient (r
s
= +0.364,p = 0.037). We demonstrated, using rigorous criteria, that periodontal and dental condition in JIA is similar to controls. In spite of that, the finding of a correlation with disease parameters provides additional evidence that increased activity and reduced functional ability underlies the deleterious effect of JIA in oral health.