The abnormal hemodynamics in Fontan circulation due to persistently increased systemic venous pressure results in hepatic venous congestion and Fontan-associated liver disease. Combined assessment of cardiac and liver fibrosis and cardiac …
Authors:
Adriana Innocenzi, Isabela Rangel, Mariana Póvoa-Corrêa, Daniella Braz Parente, Renata Perez, Rosana Souza Rodrigues, Lúcia Tomoko Fukuyama, Julia Machado Barroso, Jaime Araújo Oliveira Neto, Andréa Silvestre de Sousa, Ronir Raggio Luiz, Rosa Célia Pimentel Barbosa, Gabriel Cordeiro Camargo, Renata Moll-Bernardes
Cardiac index (CI) may be derived from the Fick method, using measured or estimated oxygen consumption (VO2), or from thermodilution. In children, LaFarge VO2 estimates correlate poorly with measured VO2 values. In a large adult cohort, there was …
Authors:
Andrew A. Lawson, Paul Tannous, Christina Laternser, Karl Migally
In the present era, the intricacy of procedures undertaken by a pediatric interventional cardiologist has increased, primarily attributed to dealing with smaller, younger patients with more complex anatomies. To adapt to these smaller and more …
The optimal dose of aspirin required in children with congenital and acquired heart disease is not known. The primary aim of this prospective observational study was to evaluate the effects of aspirin dose on platelet inhibition. The secondary aim …
Authors:
Irene E. Regan, Dermot Cox, Sean T. Kelleher, Colin J. McMahon
Mental health conditions are a common comorbidity among children living with heart disease. Children with congenital heart disease are more likely to have a mental health condition than their unaffected peers or peers with other chronic illnesses …
Authors:
Amanda D. McCormick, Kriti Puri, S. Yukiko Asaki, Shahnawaz Amdani, Devyani Chowdhury, Julie S. Glickstein, Seda Tierney, Patricia Ibeziako, Melissa K. Cousino, Christina Ronai
Infants and children with congenital heart disease (CHD) often require supplemental nutrition via tube feeding before and after surgery. Tube feeding may be required due to poor weight gain, inadequate oral-motor skills, and/or reduced endurance …
Our aim in this study is to evaluate the cardiovascular findings of pediatric patients with primary Raynaud’s phenomenon (RP) and to determine if there are any pathological findings. Our study included 42 pediatric patients aged between 7 and 18 …
Authors:
Şeyma Özpınar, Helen Bornaun, Hafize Emine Sönmez, Sümeyra Doğan, Süleyman Sönmez, Halil Harman
This study aimed to evaluate the current state of congenital interventional cardiology training worldwide, with a focus on case volumes, competency assessment, and the need for ongoing mentorship during early career stages. A survey was conducted …
Authors:
Varun Aggarwal, Gianfranco Butera, Brian Boe, Ahmet Celebi, Tacy Downing, Raul Filho Rossi, Damien Kenny, Norm Linsky, Xiangbin Pan, Kothandam Sivakumar, Wendy Whiteside, Ziyad M. Hijazi, Aimee K. Armstrong, of the PICS Society
We performed a secondary analysis of the Pediatric Heart Network (PHN) Marfan Trial public-use database to evaluate associations between extracardiac features and cardiac and aortic phenotypes in study participants. Aortic aneurysm phenotype was …
Authors:
Sheba John, Luciana T. Young, Ronald V. Lacro, Arvind Hoskoppal, Zhining Ou, Angela P. Presson, Joyce T. Johnson, Lauren Andrade, L. LuAnn Minich, Shaji Menon
Assessment of pulmonary regurgitation (PR) guides treatment for patients with congenital heart disease. Quantitative assessment of PR fraction (PRF) by echocardiography is limited. Cardiac MRI (cMRI) is the reference-standard for PRF …
Authors:
Jennifer Cohen, Son Q. Duong, Naveen Arivazhagan, David M. Barris, Surkhay Bebiya, Rosalie Castaldo, Marjorie Gayanilo, Kali Hopkins, Maya Kailas, Grace Kong, Xiye Ma, Molly Marshall, Erin A. Paul, Melanie Tan, Jen Lie Yau, Girish N. Nadkarni, David Ezon
This retrospective chart review of patients less than 18 years old with pulmonary arterial hypertension (PAH) receiving selexipag was conducted to describe selexipag dosing practices, impact on concomitant PAH therapies, and the safety and …
Authors:
Madeline Grossman, Stephen Walker, E. Zachary Ramsey
Plasma N-terminal prohormone B-type natriuretic peptide (NT-proBNP) concentration is a heart failure (HF) biomarker in adults and children. Its prognostic value for HF-related events has been established only in adults. Therefore, we aimed to test …
Authors:
Walter Schmitt, Christian Diedrich, Taye H. Hamza, Michaela Meyer, Thomas Eissing, Stefanie Breitenstein, Joseph W. Rossano, Steven E. Lipshultz
Patients with Fontan physiology have reduced exercise performance compared to their peers as well as a higher incidence of bundle branch block (BBB). This study aims to investigate the association between BBB and exercise performance in the Fontan …
Authors:
Omar Meziab, Emily Dereszkiewicz, Claudia E. Guerrero, Andrew W. Hoyer, Brent J. Barber, Scott E. Klewer, Michael D. Seckeler
Prediction of outcomes following a prenatal diagnosis of congenital heart disease (CHD) is challenging. Machine learning (ML) algorithms may be used to reduce clinical uncertainty and improve prognostic accuracy. We performed a pilot study to …
Authors:
L. E. Nield, C. Manlhiot, K. Magor, L. Freud, B. Chinni, A. Ims, N. Melamed, O. Nevo, T. Van Mieghem, D. Weisz, S. Ronzoni
This study aimed to compare the clinical characteristics and courses of pediatric patients with cardiac tumors in nonoperative and operative groups to help guide treatment decisions. We reviewed the medical records of patients diagnosed with …
Authors:
Ok Jeong Lee, Ilkun Park, Ji-Hyuk Yang, I-Seok Kang, June Huh, Jinyoung Song, Tae-Gook Jun
The use of genetic testing has enhanced the diagnostic accuracy of heritable genetic cardiomyopathies. However, it remains unclear how genetic information is interpreted and incorporated into clinical practice for children with cardiomyopathy. The …
Authors:
Justin Godown, Emily H. Kim, Melanie D. Everitt, Wendy K. Chung, Irene D. Lytrivi, Sonya Kirmani, Paul F. Kantor, Stephanie M. Ware, Jean A. Ballweg, Ashwin K. Lal, Neha Bansal, Jeffrey Towbin, Steven E. Lipshultz, Teresa M. Lee
An unusual case of of a healthy adolescent with an irregular rhythm who was found to have double ventricular response with resulting biventricular systolic dysfunction.
Authors:
Paul W. Warren, Adam W. Powell, Timothy Knilans, Chad Connor, Shankar Baskar
Parents of children in the pediatric cardiac intensive care unit (CICU) are often unprepared for family meetings (FM). Clinicians often do not follow best practices for communicating with families, adding to distress. An interprofessional team …
Authors:
Jennifer Walter, Douglas L. Hill, Arzu Cetin, Aaron DeWitt, Katie Kellom, William Quarshie, Heather Griffis, Justine Shults, Robert Arnold, Jennifer Tjia, Karen Puopolo, Martha A. Q. Curley, Chris Feudtner
Duct-dependent pulmonary circulation has traditionally been addressed by the Blalock–Taussig–Thomas shunts (BTTS). Recently, catheter-based alternatives such as ductal stenting have emerged as a particularly advantageous option, especially in …
