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Breast Cancer OnlineFirst articles

30-05-2024 | Breast Cancer | Original Article

Comparison of water- vs. land-based exercise for improving functional capacity and quality of life in patients living with and beyond breast cancer (the AQUA-FiT study): a randomized controlled trial

Breast cancer survivors (BCS) have significantly increased over the past 2 decades with over nine out of 10 patients living 5 years and beyond cancer diagnosis [ 1 ]. This improvement in survival rates has been accomplished thanks to significant …

Authors:
E. Mur-Gimeno, M. Coll, A. Yuguero-Ortiz, M. Navarro, M. Vernet-Tomás, A. Noguera-Llauradó, R. Sebio-García

29-05-2024 | Mammography | Original Article

Contrast-enhanced mammography in the management of breast architectural distortions and avoidance of unnecessary biopsies

Breast ADs are defined as a distortion of breast normal architecture without a definite visible mass according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon [ 1 ]. The underlying cause of AD can be benign such as postoperative …

Authors:
Chiara Bellini, Francesca Pugliese, Giulia Bicchierai, Francesco Amato, Diego De Benedetto, Federica Di Naro, Cecilia Boeri, Ermanno Vanzi, Giuliano Migliaro, Ludovica Incardona, Cinzia Tommasi, Lorenzo Orzalesi, Vittorio Miele, Jacopo Nori

Open Access 27-05-2024 | Breast Cancer | Original Article

A novel nomogram and survival analysis for different lymph node status in breast cancer based on the SEER database

Breast cancer is the most frequently diagnosed malignancy and is currently considered the second most common death-related malignancy in females [ 1 ]. Previous statistical studies have shown that 266,120 women in the United States suffer from …

Authors:
Lizhi Teng, Juntong Du, Shuai Yan, Peng Xu, Jiangnan Liu, Xinyang Zhao, Weiyang Tao

26-05-2024 | Repetitive Transcranial Magnetic Stimulation | Original Article

Assessing the effectiveness of high frequency repetitive transcranial magnetic stimulation for post-mastectomy pain in breast cancer patients: A randomized controlled trial

Breast cancer ranks among the most prevalent malignancies globally, with an alarming surge in its incidence [ 1 ]. Predominantly, the therapeutic approach to breast cancer in India entails surgical intervention, primarily through modified radical …

Authors:
Monika Kataria, Nishkarsh Gupta, Aasheesh Kumar, Sandeep Bhoriwal, Akanksha Singh, Varun Shekhar, Renu Bhatia

26-05-2024 | Breast Cancer | Original Article

A randomized trial of the impact of symptom monitoring using an electronic patient-reported outcome app on health-related quality of life in postmenopausal breast cancer patients receiving adjuvant endocrine therapy

Many clinical trials have shown that adjuvant endocrine therapy for hormone receptor-positive breast cancer (BC) reduces the risk of BC recurrence and mortality, and it is now standard practice to use this treatment continuously for 5–10 years [ 1 …

Authors:
Hiromi Okuyama, Fuka Takada, Naruto Taira, Seigo Nakamura

23-05-2024 | Breast Cancer | Original Article

Antitumor effects of co-treatment of resveratrol with antitumor drugs in ER- and HER2-positive breast cancer cells are due to induction of apoptosis and modulation of estrogen receptor expression

According to the Global Cancer Statistics report, breast cancer emerged as the prevailing form of cancer diagnosed in women, accounting for nearly 2.3 million new cases worldwide in 2020 [ 1 ]. Additionally, it ranked as the second major cause of …

Authors:
Beatriz Tinoco Franceschi, Patrícia Heloise Alves Bezerra, Maria Regina Torqueti

22-05-2024 | Breast Cancer | Original Article

Mesenchymal-like immune-altered is the fourth robust triple-negative breast cancer molecular subtype

Triple-negative breast cancer (TNBC) is a heterogeneous disease which is immunohistochemically characterized by a lack of estrogen receptor (ER), progesterone receptor (PR), and a lack of human epidermal growth factor receptor 2 (HER2) …

Authors:
Pascal Jézéquel, Hamza Lasla, Wilfried Gouraud, Agnès Basseville, Bertrand Michel, Jean-Sébastien Frenel, Philippe P. Juin, Fadoua Ben Azzouz, Mario Campone

18-05-2024 | Tamoxifen | Letter to the Editor

Not all patients with premenopausal breast cancer will experience the negative effects of tamoxifen treatment on their bone mineral density

Author:
Kadri Altundag

Open Access 17-05-2024 | Breast Cancer | Original Article

Resilience’s impact on quality of life and post-traumatic growth in breast cancer patients during treatment

Breast cancer continues to be the most prevalent cancer type among women. Due to the increasing incidence of breast cancer, advancements have been made in the treatment of the disease, leading to improvements in disease diagnosis and treatment …

Authors:
Songül Duran, Umut Varol, Özlem Tekir, Ahmet Hakan Soytürk

Open Access 12-05-2024 | Breast Cancer | Correction

Correction: The Japanese Breast Cancer Society Clinical Practice Guidelines for Breast Cancer, 2022 Edition: changes from the 2018 edition and general statements on breast cancer treatment

Authors:
Yutaka Yamamoto, Chikako Yamauchi, Tatsuya Toyama, Shigenori Nagai, Takehiko Sakai, Goro Kutomi, Michio Yoshimura, Masaaki Kawai, Shoichiro Ohtani, Kazunori Kubota, Kazutaka Nakashima, Naoko Honma, Masayuki Yoshida, Eriko Tokunaga, Naruto Taira, Hiroji Iwata, Shigehira Saji

Open Access 05-05-2024 | Radiotherapy | Original Article

Simultaneous integrated boost intensity-modulated radiotherapy post breast-conserving surgery: clinical efficacy, adverse effects, and cosmetic outcomes in breast cancer patients

Breast cancer has become the most prevalent cancer among women, accounting for 11.7% of all global cancer cases [ 1 ]. This increase emphasizes the necessity for effective and efficient treatment strategies. The evolution of diagnostic and …

Authors:
Yong-qiang Bao, Teng-hua Yu, Wei Huang, Qing-feng Mao, Gan-jie Tu, Bin Li, An Yi, Jin-gao Li, Jun Rao, Huai-wen Zhang, Chun-ling Jiang

Open Access 29-04-2024 | Anthracycline | Original Article

Real-world data of HER2-negative early breast cancer patients treated with anthracycline and/or taxane regimens in Japan

Breast cancer is one of the most common malignancies in the world and the leading cause of cancer-related death among women [ 1 , 2 ]. Compared with other malignancies in Japanese women, breast cancer has the highest age-adjusted mortality rate …

Authors:
Akihiko Shimomura, Yasuaki Sagara, Ryo Koto, Masakazu Fujiwara, Yuka Kanemura, Hiroshi Kitagawa, Shigehira Saji

Open Access 27-04-2024 | Breast Cancer | Original Article

Percutaneous ultrasound-guided cryoablation for early-stage primary breast cancer: a follow-up study in Japan

Over the past two decades, the widespread adoption of screening mammography and advances in imaging have facilitated the detection of small early-stage breast tumors. This, alongside the successful demonstration of good local tumor control using …

Authors:
Hisanori Kawamoto, Koichiro Tsugawa, Yuko Furuya, Kaori Sakamaki, Sayoko Kakimoto, Mina Kitajima, Mariko Nagai Takishita, Mizuho Tazo, Mari Hara Nakano, Takako Kuroda, Ayaka Shimo, Arata Shimo, Yasuyuki Kojima, Makiko Tsuzuki, Ai Motoyoshi, Ei Haku, Toru Nishikawa, Yoshihide Kanemaki, Hidefumi Mimura, Mamoru Fukuda

27-04-2024 | Tamoxifen | Original Article

Adverse effects of tamoxifen treatment on bone mineral density in premenopausal patients with breast cancer: a systematic review and meta-analysis

Since the 1970s, tamoxifen has been one of the most effective and widely used anti-cancer drugs in patients with breast cancer [ 1 , 2 ]. Adjuvant tamoxifen therapy after primary surgical treatment markedly reduces the risk of recurrence of breast …

Authors:
Soo Jin Lee, Chihwan David Cha, Hanpyo Hong, Yun Young Choi, Min Sung Chung

23-04-2024 | Breast Cancer | Special Feature

Perspectives for the clinical application of ctDNA analysis to breast cancer drug therapy

Circulating tumor DNA (ctDNA) consists of DNA fragments released from cancer cells into the blood circulation with quick clearance. Analysis of ctDNA can enable real-time assessment of the presence of cancer cells and their genomic …

Author:
Tetsuhiro Yoshinami

23-04-2024 | Breast Cancer | Original Article

Global untargeted and individual targeted plasma metabolomics of breast cancer recurrence modified by hormone receptors

According to data from the World Health Organization (WHO) in 2020, there were about 2.3 million newly diagnosed breast cancer patients and 685,000 deaths from breast cancer in women worldwide. Breast cancer is a heterogeneous disease with …

Authors:
Pei-Jing Yang, Eing-Mei Tsai, Ming-Feng Hou, Yen-Jung Lee, Tsu-Nai Wang

22-04-2024 | Cytostatic Therapy | Letter to the Editor

Number of lines of previous chemotherapy regimen might affect the oucome of sacituzumab govitecan in metastatic triple-negative breast cancer patients

Author:
Kadri Altundag

Open Access 21-04-2024 | Breast Cancer | Original Article

Comparing survival outcomes between neoadjuvant and adjuvant chemotherapy within T2N1M0 stage hormone receptor-positive, HER2-negative breast cancer: a retrospective cohort study based on SEER database

Neoadjuvant or preoperative chemotherapy (NACT), defined as the administration of chemotherapy before surgery, was initially the standard treatment for patients with locally advanced breast cancer. Currently, it is becoming a commonly used option …

Authors:
Yuhang Shang, Xuelian Wang, Yansong Liu, Weilun Cheng, Yunqiang Duan, Zhengbo Fang, Jiangwei Liu, Fanjing Kong, Ting Wang, Tianshui Yu, Anbang Hu, Jiarui Zhang, Hanyu Zhang, Mingcui Li, Zhiyuan Rong, Yanling Li, Suborna S. Shakila, Xinxin Li, Jianyuan Feng, Fei Ma, Baoliang Guo

Open Access 21-04-2024 | Breast Cancer | Original Article

Concordance of HER2 status between core needle biopsy and surgical resection specimens of breast cancer: an analysis focusing on the HER2-low status

Breast cancer is a heterogeneous disease, and accurate determination of basic biomarkers including estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) is crucial for selecting appropriate …

Authors:
Sei Na, Milim Kim, Yujun Park, Hyun Jung Kwon, Hee-Chul Shin, Eun-Kyu Kim, Mijung Jang, Sun Mi Kim, So Yeon Park

Open Access 20-04-2024 | Breast Cancer | Original Article

Real-world progression-free survival and overall survival of palbociclib plus endocrine therapy (ET) in Japanese patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer in the first-line or second-line setting: an observational study

Despite substantial advances in therapy, advanced breast cancer (ABC) remains an incurable disease with a 5-year survival rate of ~ 25% [ 1 ]. Of the different disease subtypes, hormone receptor-positive (HR+)/human epidermal growth factor receptor …

Authors:
Tetsuhiro Yoshinami, Shigenori E. Nagai, Masaya Hattori, Takuho Okamura, Kenichi Watanabe, Takahiro Nakayama, Hiroko Masuda, Michiko Tsuneizumi, Daisuke Takabatake, Michiko Harao, Hiroshi Yoshino, Natsuko Mori, Hiroyuki Yasojima, Chiya Oshiro, Madoka Iwase, Miki Yamaguchi, Takafumi Sangai, Nobuyoshi Kosaka, Kentaro Tajima, Norikazu Masuda