Creutzfeldt–Jakob disease (CJD) is a classic member of the group of prion diseases and is characterized by progressive degeneration of nervous system structures with a variety of neurological symptoms, steady progression, and inevitable death. The …
Spinal muscular atrophy (SMA) is a group of genetically heterogeneous neuromuscular diseases characterized by progressive loss of motor neurons in the anterior horns of the spinal cord. The prevalence of SMA is approximately 1 case per 10,000 live …
This literature review assesses data obtained over the past 10 years on the relationship between inflammatory markers and the severity of negative symptoms in schizophrenia. A systematic search of the PubMed, Mendeley, and eLibrary databases was …
Schizophrenia is a severe mental disorder whose etiology and pathogenesis are significantly influenced by hereditary factors. Genome-wide association studies have shown that most genetic variants associated with high risk of schizophrenia are …
Tremor is one of the main motor symptoms of Parkinson’s disease, though its pathophysiology remains largely unknown. The research and clinical task is complicated by the clinical and pathomorphological heterogeneity of tremor and unpredictable …
Parkinson’s disease (PD) produces both motor and non-motor symptoms, and among these an important position is occupied by cognitive impairment. This article provides an overview of the spectrum of cognitive impairment in PD, with analysis of their …
Spinal cord stimulation is a minimally invasive surgical technique which has been in successful use for a long time in the treatment of chronic pain syndromes. Over the past 15 years, many reports on the use of spinal stimulation in patients with …
This literature review addresses the problems of the relationship between dementia and depression, the role of depression as a risk factor for the development of dementia, and the place of depression in the structure of neurocognitive impairment …
A molecular genetic approach to studying childhood epilepsy helps to understand the role of heredity in its development and to provide a personalized approach to the treatment and rehabilitation of severe and often refractory forms of epilepsy.
We present here a clinical case of a teenage patient illustrating the difficulties of diagnosis and treatment of mental pathology at the onset of juvenile parkinsonism developing as a result of compound heterozygous mutations and proceeding with …
This article describes an experimental apparatus developed to evaluate solutions found by rats to the Piaget object permanence test, which assesses the animals’ ability to operate one of the simplest empirical laws, “permanence” (as defined by …
Indications for cochlear implantation (CI) are constantly expanding beyond severe and profound deafness to include patients with unilateral deafness and, more recently, congenital anatomical malformations of the inner ear [Karamert et al., 2022].
A rippled-spectrum sound signal has an envelope periodicity which is not present in a continuous-spectrum signal. The studies reported here investigated the role of the signal envelope in the task of discriminating signals with rippled spectra.
This work continues a cycle of psychophysical experiments investigating the characteristics of the recognition of visual stimuli of different colors and different sizes by children of early preschool age. Measurements were made using a game-based …
Postlingually deafened patients, in contrast to those losing their hearing at an early age retain previously formed control based on the direct connection between hearing and speech. In addition, patients with hearing impairment show changes in …
We report here the first research into the specificity of the frequency effects of release from stimulus-specific adaptation in the activity of single neurons in the primary fields of the auditory cortex of house mice in the awake state. After …
Patients with diabetes mellitus have decreased olfactory function as compared with healthy individuals. Hyposmia is more common in type 2 diabetes (DM2) and is characterized by a decreased ability to recognize odors accompanied by deterioration of …
The ability of highly automated vehicles (HAV) to determine the position of objects in three-dimensional space plays a key role in planning their movement. Implementation of algorithms solving this problem is especially challenging for systems …
